Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ioana, Sandu"'
Autor:
Marian Aurel Taulescu, Andrada Negoescu, Andrei Ungur, Corina Toma, Angela Monica Ionică, Claudiu Gal, Ioana Sandu, Alexandru Buzdea, Andrei Tutuneanu, Mihai Turcitu, Ioan Emilian Horvat, Georgiana Deak
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionAngiostrongylus vasorum (A. vasorum) is a widely distributed gastropod-borne nematode, causing severe cardio-pulmonary disorders in dogs. In Romania, A. vasorum was detected in foxes and serologically confirmed in domestic dogs, but no cl
Externí odkaz:
https://doaj.org/article/8fc47350abf345598e5bbd8d418806b4
Autor:
Andreas Agrafiotis, Daniel Neumeier, Kai-Lin Hong, Tasnia Chowdhury, Roy Ehling, Raphael Kuhn, Ioana Sandu, Victor Kreiner, Tudor-Stefan Cotet, Danielle Shlesinger, Daria Laslo, Stine Anzböck, Dale Starkie, Daniel J. Lightwood, Annette Oxenius, Sai T. Reddy, Alexander Yermanos
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106055- (2023)
Summary: Although new genomics-based pipelines have potential to augment antibody discovery, these methods remain in their infancy due to an incomplete understanding of the selection process that governs B cell clonal selection, expansion, and antige
Externí odkaz:
https://doaj.org/article/3943d2618c1d4c6c93b112efcb9e898c
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Excess antigenic exposure, such as in cancers or chronic viral infection, can lead to T cell exhaustion. Here the authors show that despite high exposure to antigen in the context of chronic LCMV infection in mice, exhausted CD8+ T cells have low lev
Externí odkaz:
https://doaj.org/article/0847b4efc9ab451ba66c78afdb12de6e
Autor:
Suzanne P. M. Welten, Alexander Yermanos, Nicolas S. Baumann, Franziska Wagen, Nathalie Oetiker, Ioana Sandu, Alessandro Pedrioli, Jennifer D. Oduro, Sai T. Reddy, Luka Cicin-Sain, Werner Held, Annette Oxenius
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.
Externí odkaz:
https://doaj.org/article/ba32f60be74545d6b1590448839902d6
Autor:
Raphael Kuhn, Ioana Sandu, Andreas Agrafiotis, Kai-Lin Hong, Danielle Shlesinger, Daniel Neimeier, Doron Merkler, Annette Oxenius, Sai T. Reddy, Alexander Yermanos
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD8+ T cells play a crucial role in the control and resolution of viral infections and can adopt a wide range of phenotypes and effector functions depending on the inflammatory context and the duration and extent of antigen exposure. Similarly, viral
Externí odkaz:
https://doaj.org/article/3fe6fda7adbd4b97a8c9ea15e226f3d6
Autor:
Ioana Sandu, Dario Cerletti, Nathalie Oetiker, Mariana Borsa, Franziska Wagen, Ilaria Spadafora, Suzanne P.M. Welten, Ugne Stolz, Annette Oxenius, Manfred Claassen
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108078- (2020)
Summary: A hallmark of chronic infections is the presence of exhausted CD8 T cells, characterized by a distinct transcriptional program compared with functional effector or memory cells, co-expression of multiple inhibitory receptors, and impaired ef
Externí odkaz:
https://doaj.org/article/d6da9e5548be4a6f82dcc718fcd85cb0
Autor:
Alexander Yermanos, Ioana Sandu, Alessandro Pedrioli, Mariana Borsa, Franziska Wagen, Nathalie Oetiker, Suzanne P. M. Welten, Katharina Pallmer, Sai T. Reddy, Annette Oxenius
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CD8 T cells play a crucial role in providing protection from viral infections. It has recently been established that a subset of CD8 T cells expressing Tcf1 are responsible for sustaining exhausted T cells during chronic lymphocytic choriomeningitis
Externí odkaz:
https://doaj.org/article/1a477170752c4533a2dbb84ed90972bd
Autor:
Danielle Shlesinger, Kai-Lin Hong, Ghazal Shammas, Nicolas Page, Ioana Sandu, Andreas Agrafiotis, Victor Kreiner, Nicolas Fonta, Ilena Vincenti, Ingrid Wagner, Margot Piccinno, Alexandre Mariotte, Bogna Klimek, Raphael Dizerens, Marcos Manero-Carranza, Raphael Kuhn, Roy Ehling, Lester Frei, Keywan Khodaverdi, Camilla Panetti, Nicole Joller, Annette Oxenius, Doron Merkler, Sai T. Reddy, Alexander Yermanos
Publikováno v:
Genes and Immunity, 23
Adaptive immune repertoires are composed by the ensemble of B and T-cell receptors within an individual, reflecting both past and current immune responses. Recent advances in single-cell sequencing enable recovery of the complete adaptive immune rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd78ebfdf3c1a41bac0cd5529f218e5
https://doi.org/10.1038/s41435-022-00180-w
https://doi.org/10.1038/s41435-022-00180-w
Autor:
Ioana Sandu, Annette Oxenius
Publikováno v:
Immunological Reviews.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25e05d4c0d9543ec5c7098b92d67ae83
https://doi.org/10.1111/imr.13203
https://doi.org/10.1111/imr.13203
Autor:
Ioana SANDU, Gabriela DRAGAN
Publikováno v:
CES Working Papers, Vol 8, Iss 3, Pp 464-472 (2016)
The EU is permanently trying to secure its proximity by creating a “ring of friends” in the neighbourhood. Thus, stabilization through economic integration and modernization have been the purpose of the European Neighbourhood Policy (the ENP) sin
Externí odkaz:
https://doaj.org/article/31df125902e44a169c259647fcf5ae9e