Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ioana, Plesca"'
Autor:
Johanna Kirchner, Ioana Plesca, Rebecca Rothe, Antonia Resag, Steffen Löck, Iva Benešová, Luise Rupp, Annett Linge, Rebekka Wehner, Mechthild Krause, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide, with human papillomavirus (HPV) infection contributing to cancer development. Conventional therapies achieve only limited efficiency, especially in recu
Externí odkaz:
https://doaj.org/article/2da60e4d39b345af92e2abb592f98e57
Autor:
Max Heiduk, Ioana Plesca, Jessica Glück, Luise Müller, David Digomann, Charlotte Reiche, Janusz von Renesse, Rahel Decker, Christoph Kahlert, Ulrich Sommer, Daniela E. Aust, Marc Schmitz, Jürgen Weitz, Lena Seifert, Adrian M. Seifert
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. At diagnosis, only 20% of patients with PDAC are eligible for primary resection. Neoadjuvant chemotherapy can enable surgical resection in 30%–40% of patients with locally a
Externí odkaz:
https://doaj.org/article/9a5a29027fcc4aadb45aea3cef95ab9a
Autor:
Ulrich Sommer, Jürgen Weitz, Daniela Aust, Maximilian Kießler, Ioana Plesca, Rebekka Wehner, Friederike Wilczkowski, Luise Müller, Antje Tunger, Xixi Lai, Anke Rentsch, Adrian M Seifert, Lena Seifert, Michael Bachmann, Martin Bornhäuser, Gustavo Baretton, Marc Schmitz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Plasmacytoid dendritic cells (pDCs) play a key role in the induction and maintenance of antitumor immunity. Conversely, they can act as tolerogenic DCs by inhibiting tumor-directed immune responses. Therefore, pDCs may profoundly influence
Externí odkaz:
https://doaj.org/article/47849b5e9eeb4ac59685008f84a1679c
Autor:
Ioana Plesca, Antje Tunger, Luise Müller, Rebekka Wehner, Xixi Lai, Marc-Oliver Grimm, Sergio Rutella, Michael Bachmann, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The tumor immune contexture plays a major role for the clinical outcome of patients. High densities of CD45RO+ T helper 1 cells and CD8+ T cells are associated with improved survival of patients with various cancer entities. In contrast, a higher fre
Externí odkaz:
https://doaj.org/article/1bfe7fe5c6024be1963558088d27f31e
Autor:
Luise Müller, Antje Tunger, Ioana Plesca, Rebekka Wehner, Achim Temme, Dana Westphal, Friedegund Meier, Michael Bachmann, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cancer stem cells (CSCs), also known as tumor-initiating cells, are characterized by an increased capacity for self-renewal, multipotency, and tumor initiation. While CSCs represent only a small proportion of the tumor mass, they significantly accoun
Externí odkaz:
https://doaj.org/article/7e84597c0e1b42fca64fa09a625f4a68
Autor:
Felix Wagner, Ulrike Hölig, Friederike Wilczkowski, Ioana Plesca, Ulrich Sommer, Rebekka Wehner, Maximilian Kießler, Armin Jarosch, Katharina Flecke, Maia Arsova, Antje Tunger, Andreas Bogner, Christoph Reißfelder, Jürgen Weitz, Knut Schäkel, Esther G. C. Troost, Mechthild Krause, Gunnar Folprecht, Martin Bornhäuser, Michael P. Bachmann, Daniela Aust, Gustavo Baretton, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neoadjuvant radiochemotherapy (nRCT) can significantly influence the tumor immune architecture that plays a pivotal role in regulating tumor growth. Whereas, various studies have investigated the effect of nRCT on tumor-infiltrating T cells, little i
Externí odkaz:
https://doaj.org/article/030ea4ff884e4213904d09e1d8759f7a
Autor:
David Digomann, Johannes Strack, Max Heiduk, Ioana Plesca, Luise Rupp, Charlotte Reiche, Simone Nicolaus, Carolin Beer, Ulrich Sommer, Marc Schmitz, Marius Distler, Jürgen Weitz, Adrian M. Seifert, Lena Seifert
Publikováno v:
Cancers; Volume 15; Issue 8; Pages: 2326
Immunotherapy has shown promising results in multiple solid tumors and hematological malignancies. However, pancreatic ductal adenocarcinoma (PDAC) has been largely refractory to current clinical immunotherapies. The V-domain Ig suppressor of T-cell
Publikováno v:
European Journal of Immunology. 52:1750-1758
DCs play a pivotal role in orchestrating innate and adaptive antitumor immunity. Activated DCs can produce large amounts of various proinflammatory cytokines, initiate T-cell responses, and exhibit direct cytotoxicity against tumor cells. They also e
Autor:
Ioana Plesca, Iva Benešová, Carolin Beer, Ulrich Sommer, Luise Müller, Rebekka Wehner, Max Heiduk, Daniela Aust, Gustavo Baretton, Michael P Bachmann, Anja Feldmann, Jürgen Weitz, Lena Seifert, Adrian M Seifert, Marc Schmitz
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1216
Dendritic cells (DCs) play a key role in the orchestration of antitumor immunity. Activated DCs efficiently enhance antitumor effects mediated by natural killer cells and T lymphocytes. Conversely, tolerogenic DCs essentially contribute to an immunos
Autor:
Maximilian, Kießler, Ioana, Plesca, Ulrich, Sommer, Rebekka, Wehner, Friederike, Wilczkowski, Luise, Müller, Antje, Tunger, Xixi, Lai, Anke, Rentsch, Kenneth, Peuker, Sebastian, Zeissig, Adrian M, Seifert, Lena, Seifert, Jürgen, Weitz, Michael, Bachmann, Martin, Bornhäuser, Daniela, Aust, Gustavo, Baretton, Marc, Schmitz
Publikováno v:
Journal for Immunotherapy of Cancer
Background Plasmacytoid dendritic cells (pDCs) play a key role in the induction and maintenance of antitumor immunity. Conversely, they can act as tolerogenic DCs by inhibiting tumor-directed immune responses. Therefore, pDCs may profoundly influence