Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ioan Iacovache"'
Autor:
Lea Gigon, Philipp Müller, Beat Haenni, Ioan Iacovache, Maruša Barbo, Gordana Gosheva, Shida Yousefi, Alice Soragni, Christoph von Ballmoos, Benoît Zuber, Hans-Uwe Simon
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114084- (2024)
Summary: Eosinophils play a crucial role in host defense while also contributing to immunopathology through the release of inflammatory mediators. Characterized by distinctive cytoplasmic granules, eosinophils securely store and rapidly release vario
Externí odkaz:
https://doaj.org/article/d182e05a08354491ada376f038ee4c1c
Autor:
Matej Milijaš Jotić, Anastasija Panevska, Ioan Iacovache, Rok Kostanjšek, Martina Mravinec, Matej Skočaj, Benoît Zuber, Ana Pavšič, Jaka Razinger, Špela Modic, Francesco Trenti, Graziano Guella, Kristina Sepčić
Publikováno v:
Toxins, Vol 13, Iss 7, p 455 (2021)
Ostreolysin A6 (OlyA6) is a protein produced by the oyster mushroom (Pleurotus ostreatus). It binds to membrane sphingomyelin/cholesterol domains, and together with its protein partner, pleurotolysin B (PlyB), it forms 13-meric transmembrane pore com
Externí odkaz:
https://doaj.org/article/c3399cff5a9c4bd48ea26b2a29274cc4
Autor:
Ioan Iacovache, Sacha De Carlo, Nuria Cirauqui, Matteo Dal Peraro, F. Gisou van der Goot, Benoît Zuber
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Aerolysin is a secreted bacterial pore forming toxin that inserts into the host plasma membrane, potentially leading to cell death. Here the authors present Cryo-EM structures of aerolysin arrested at different stages of the pore formation process th
Externí odkaz:
https://doaj.org/article/cf673eee03eb4a2b9b6bf3aad1ad1011
Autor:
Onya Opota, Isabelle Vallet-Gély, Renaud Vincentelli, Christine Kellenberger, Ioan Iacovache, Manuel Rodrigo Gonzalez, Alain Roussel, Françoise-Gisou van der Goot, Bruno Lemaitre
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002259 (2011)
Pseudomonas entomophila is an entomopathogenic bacterium that infects and kills Drosophila. P. entomophila pathogenicity is linked to its ability to cause irreversible damages to the Drosophila gut, preventing epithelium renewal and repair. Here we r
Externí odkaz:
https://doaj.org/article/38015d4decfb4c639a0ce5075303d43b
Autor:
Ioan Iacovache, Matteo T Degiacomi, Lucile Pernot, Sylvia Ho, Marc Schiltz, Matteo Dal Peraro, F Gisou van der Goot
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002135 (2011)
Throughout evolution, one of the most ancient forms of aggression between cells or organisms has been the production of proteins or peptides affecting the permeability of the target cell membrane. This class of virulence factors includes the largest
Externí odkaz:
https://doaj.org/article/797d55a4f57141e19f10db5aefa4b5a9
Autor:
Pawel Szczesny, Ioan Iacovache, Anna Muszewska, Krzysztof Ginalski, F Gisou van der Goot, Marcin Grynberg
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20349 (2011)
A number of bacterial virulence factors have been observed to adopt structures similar to that of aerolysin, the principal toxin of Aeromonas species. However, a comprehensive description of architecture and structure of the aerolysin-like superfamil
Externí odkaz:
https://doaj.org/article/3b7add04c04b4220bcc85524a89e8d5d
Publikováno v:
Bioconjugate Chemistry. 34:70-77
The precise arrangement of structural subunits is a key factor for the proper shape and function of natural and artificial supramolecular assemblies. In DNA nanotechnology, the geometrically well-defined double-stranded DNA scaffold serves as an elem
Autor:
Norbert Polacek, Ioan Iacovache, Julia Reuther, Walid H. Gharib, Andreas Pircher, Benoît Zuber, Lukas Schneider
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
Reuther, Julia; Schneider, Lukas; Iacovache, Ioan; Pircher, Andreas; Gharib, Walid H.; Zuber, Benoît; Polacek, Norbert (2021). A small ribosome-associated ncRNA globally inhibits translation by restricting ribosome dynamics. RNA biology, 18(12), pp. 2617-2632. Taylor and Francis 10.1080/15476286.2021.1935573
article-version (VoR) Version of Record
Reuther, Julia; Schneider, Lukas; Iacovache, Ioan; Pircher, Andreas; Gharib, Walid H.; Zuber, Benoît; Polacek, Norbert (2021). A small ribosome-associated ncRNA globally inhibits translation by restricting ribosome dynamics. RNA biology, 18(12), pp. 2617-2632. Taylor and Francis 10.1080/15476286.2021.1935573
Ribosome-associated non-coding RNAs (rancRNAs) have been recognized as an emerging class of regulatory molecules capable of fine-tuning translation in all domains of life. RancRNAs are ideally suited for allowing a swift response to changing environm
Autor:
Simon Rothenbühler, Adrian Gonzalez, Ioan Iacovache, Simon M. Langenegger, Benoît Zuber, Robert Häner
Publikováno v:
Rothenbühler, Simon; Gonzalez, Adrian; Iacovache, Ioan; Langenegger, Simon M.; Zuber, Benoît; Häner, Robert (2022). Tetraphenylethylene–DNA conjugates: influence of sticky ends and DNA sequence length on the supramolecular assembly of AIE-active vesicles. Organic & biomolecular chemistry, 20(18), pp. 3703-3707. Royal Society of Chemistry 10.1039/D2OB00357K
The supramolecular assembly of DNA conjugates, functionalized with tetraphenylethylene (TPE) sticky ends, into vesicular structures is described. The aggregation-induced emission (AIE) active TPE units allow to monitor the assembly process by fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacaeb2fd63579c3fd7cafde3e1813b5