Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ioakeim Ampartzidis"'
Autor:
Gabriel L. Galea, Eirini Maniou, Timothy J. Edwards, Abigail R. Marshall, Ioakeim Ampartzidis, Nicholas D. E. Greene, Andrew J. Copp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Mutations that cause tissue mosaicism have been identified in individuals with severe congenital defects. Here, the authors show that mosaic deletion of Vangl2 in the murine neuroepithlium causes spina bifida by preventing apical constriction via red
Externí odkaz:
https://doaj.org/article/52e4848101894d13b8f2a7a3e588a063
Autor:
Gabriel L. Galea, Eirini Maniou, Timothy J. Edwards, Abigail R. Marshall, Ioakeim Ampartzidis, Nicholas D. E. Greene, Andrew J. Copp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/b734718cc4534036baddc2e2aa44a9d3
Autor:
Ioakeim Ampartzidis, Christoforos Efstathiou, Francesco Paonessa, Elliott M Thompson, Tyler Wilson, Conor J McCann, Nicholas DE Greene, Andrew Copp, Frederick J Livesey, Nicola Elvassore, Giovanni Giuseppe Giobbe, Paolo De Coppi, Eirini Maniou, Gabriel L Galea
Publikováno v:
Developmental biology.
Neuroepithelial cells balance tissue growth requirement with the morphogenetic imperative of closing the neural tube. They apically constrict to generate mechanical forces which elevate the neural folds, but are thought to apically dilate during mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67494b7335124d1202d3303c853afd98
https://pubmed.ncbi.nlm.nih.gov/36509125
https://pubmed.ncbi.nlm.nih.gov/36509125
Autor:
Clara Munger, Timo N. Kohler, Erin Slatery, Anna L. Ellermann, Sophie Bergmann, Christopher A. Penfold, Ioakeim Ampartzidis, Yutong Chen, Florian Hollfelder, Thorsten E. Boroviak
Publikováno v:
Development (Cambridge, England). 149(20)
Funder: Wellcome Trust; Id: http://dx.doi.org/10.13039/100010269
Funder: Royal Society; Id: http://dx.doi.org/10.13039/501100000288
Funder: AstraZeneca; Id: http://dx.doi.org/10.13039/100004325
Funder: University of Cambridge; Id: http
Funder: Royal Society; Id: http://dx.doi.org/10.13039/501100000288
Funder: AstraZeneca; Id: http://dx.doi.org/10.13039/100004325
Funder: University of Cambridge; Id: http
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6ff95a3aa5fd46f935143a959e8d6b
https://pubmed.ncbi.nlm.nih.gov/36125063
https://pubmed.ncbi.nlm.nih.gov/36125063
Autor:
Abigail R. Marshall, Gabriel L. Galea, Andrew J. Copp, Timothy J. Edwards, Eirini Maniou, Nicholas D. E. Greene, Ioakeim Ampartzidis
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Post-zygotic mutations that generate tissue mosaicism are increasingly associated with severe congenital defects, including those arising from failed neural tube closure. Here we report that neural fold elevation during mouse spinal neurulation is vu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a47d95b1b131cdec3d996b237c13c0
http://europepmc.org/articles/PMC7895924
http://europepmc.org/articles/PMC7895924