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pro vyhledávání: '"Io Guane Rivera"'
Autor:
Douglass J. Forbes, Maho Niwa, Daniel K. Nomura, Lindsay S. Roberts, Arvin B. Tam, Io Guane Rivera, Vivek Chandra
Publikováno v:
Developmental Cell. 46:327-343.e7
The unfolded protein response (UPR) is induced by proteotoxic stress of the endoplasmic reticulum (ER). Here we report that ATF6, a major mammalian UPR sensor, is also activated by specific sphingolipids, dihydrosphingosine (DHS) and dihydroceramide