Light-based gamma entrainment with novel invisible spectral flicker stimuli

Autor: Luna S. Hansen, Marcus H. Carstensen, Mark A. Henney, N. Mai Nguyen, Martin W. Thorning-Schmidt, Jes Broeng, Paul Michael Petersen, Tobias S. Andersen

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Light-based gamma entrainment using sensory stimuli (GENUS) shows considerable potential for the treatment of Alzheimer’s disease (AD) in both animal and human models. While the clinical efficacy of GENUS for AD is paramount, its effective

Externí odkaz: https://doaj.org/article/1dc3f60347144b7bbe0adb7a7527b76c

Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker versus Placebo in Patients with Mild-to-Moderate Alzheimer’s Disease: A Randomized, Placebo-Controlled, Double-Blinded, Pilot Study

Autor: Mikkel Pejstrup Agger, Else Rubæk Danielsen, Marcus Schultz Carstensen, N. Mai Nguyen, Maibritt Horning, Mark Alexander Henney, Christopher Boe Ravn Jensen, Anders Ohlhues Baandrup, Troels Wesenberg Kjær, Kristoffer Hougaard Madsen, Kamilla Miskowiak, Paul Michael Petersen, Peter Høgh

Publikováno v: Agger, M P, Danielsen, E R, Carstensen, M S, Nguyen, N M, Horning, M, Henney, M A, Jensen, C B R, Baandrup, A O, Kjaer, T W, Madsen, K H, Miskowiak, K W, Petersen, P M & Høgh, P 2023, ' Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker versus Placebo in Patients with Mild-to-Moderate Alzheimer’s Disease : A Randomized, Placebo-Controlled, Double-Blinded, Pilot Study ', Journal of Alzheimer's Disease, vol. 92, no. 2, pp. 653-665 . https://doi.org/10.3233/JAD-221238

Background: Recent studies suggested induction of 40 Hz neural activity as a potential treatment for Alzheimer’s disease (AD). However, prolonged exposure to flickering light raises adherence and safety concerns, encouraging investigation of tolera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a562e9f39e60247fad7997f1361a01ce
https://doi.org/10.3233/jad-221238

Novel Invisible Spectral Flicker Induces 40 Hz Neural Entrainment with Similar Spatial Distribution as 40 Hz Stroboscopic Light

Autor: Mikkel Pejstrup Agger, Marcus Schultz Carstensen, Mark Alexander Henney, Luna Skytte Hansen, Anders Ohlhues Baandrup, Mai Nguyen, Paul Michael Petersen, Kristoffer Hougaard Madsen, Troels Wesenberg Kjær

Publikováno v: Agger, M P, Carstensen, M S, Henney, M A, Hansen, L S, Baandrup, A O, Nguyen, M, Petersen, P M, Madsen, K H & Kjær, T W 2022, ' Novel Invisible Spectral Flicker Induces 40 Hz Neural Entrainment with Similar Spatial Distribution as 40 Hz Stroboscopic Light ', Journal of Alzheimer's Disease, vol. 88, no. 1, pp. 335-344 . https://doi.org/10.3233/JAD-220081

Background: Exposure to 40 Hz stroboscopic light, for one hour a day, has previously been published as a potential treatment option for Alzheimer’s disease in animal models. However, exposure for an hour a day to 40 Hz stroboscopic light can be str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f062c77cad9d31e70ee58bc56b68dc3c
https://doi.org/10.3233/jad-220081

40 Hz invisible spectral flicker and its potential use in Alzheimer's light therapy treatment

Autor: Dennis Dan Corell, Luna S. Hansen, Jes Broeng, Gustavo M. Feijóo Carrillo, Paul Michael Petersen, Lance J. Kriegsfeld, N. Mai Nguyen, Henrik Enggaard Hansen, Johannes Lindén, Marcus S. Carstensen

Publikováno v: Carstensen, M S, Lindén, J, Nguyen, N M, Hansen, H E, Feijóo Carrillo, G M, Hansen, L S, Corell, D D, Broeng, J, Kriegsfeld, L J & Petersen, P M 2020, 40 Hz invisible spectral flicker and its potential use in Alzheimer's light therapy treatment . in M R Hamblin, J D Carroll & P Arany (eds), Proceedings of SPIE . vol. 11221, 112210L, SPIE-International Society for Optical Engineering, Progress in Biomedical Optics and Imaging-Proceedings of SPIE, Mechanisms of Photobiomodulation Therapy XV 2020, San Francisco, California, United States, 11/03/2020 . https://doi.org/10.1117/12.2544338

Alzheimer's disease (AD) not only takes an emotional toll on the individual with the disease, their families, relatives, and caretakers, it also has immense socioeconomic consequences on the health care system and society. Moreover, the socioeconomic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7459e3db0ea5144c1a4bc2c8e7bda566
https://orbit.dtu.dk/en/publications/14932a1c-b313-4858-9057-dc3099379e24

40 Hz invisible spectral flicker and its potential use in Alzheimer's light therapy treatment

Autor: Hamblin, Michael R., Carroll, James D., Arany, Praveen, Carstensen, Marcus S., Lindén, Johannes, Nguyen, N. Mai, Hansen, Henrik E., Feijóo Carrillo, Gustavo M., Hansen, Luna S., Corell, Dennis D., Broeng, Jes, Kriegsfeld, Lance J., Petersen, Paul Michael

Publikováno v: Proceedings of SPIE; March 2020, Vol. 11221 Issue: 1 p112210L-112210L-12, 11108803p