Zobrazeno 1 - 10
of 2 819
pro vyhledávání: '"Invadopodia"'
Publikováno v:
Microbial Cell, Vol 11, Pp 288-311 (2024)
The role of model organisms such as yeasts in life science research is crucial. Although the baker’s yeast (Saccharomyces cerevisiae) is the most popular model among yeasts, the contribution of the fission yeasts (Schizosaccharomyces) to life scien
Externí odkaz:
https://doaj.org/article/4b29eec1ad7e460faaa6c878ce675902
Autor:
Junnan Liu, Xue Wang, Wencheng Jiang, Anca Azoitei, Tim Eiseler, Markus Eckstein, Arndt Hartmann, Stephan Stilgenbauer, Mohamed Elati, Meike Hohwieler, Alexander Kleger, Axel John, Felix Wezel, Friedemann Zengerling, Christian Bolenz, Cagatay Günes
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-29 (2024)
Abstract Background We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor formation in xenogra
Externí odkaz:
https://doaj.org/article/f3dd2d1ae1494471a8095c3f91f82dd1
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Tumor‐derived extracellular vesicles (EVs) are potential biomarkers for tumors, but their reliable molecular targets have not been identified. The previous study confirms that ubiquitin‐specific protease 22 (USP22) promotes lung adenocar
Externí odkaz:
https://doaj.org/article/cb37fa90ab534d4bbe64599f021eb9f0
Akademický článek
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Autor:
Immanuel Desel, Susanne Jung, Nikolai Purcz, Yahya Açil, Christoph Sproll, Johannes Kleinheinz, Sonja Sielker
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 8, Pp 6927-6940 (2023)
Successful treatment for any type of carcinoma largely depends on understanding the patterns of invasion and migration. For oral squamous cell carcinoma (OSCC), these processes are not entirely understood as of now. Invadopodia and podosomes, called
Externí odkaz:
https://doaj.org/article/2ab79c6833ba4150b769868289be5a9f
Autor:
Koji Saito, Sakino Ozawa, Yosuke Chiba, Ruri Takahashi, Ryoya Ogomori, Kojiro Mukai, Tomohiko Taguchi, Hiroyasu Hatakeyama, Yasutaka Ohta
Publikováno v:
Cell Structure and Function, Vol 48, Iss 2, Pp 161-174 (2023)
Invadopodia are protrusive structures that mediate the extracellular matrix (ECM) degradation required for tumor invasion and metastasis. Rho small GTPases regulate invadopodia formation, but the molecular mechanisms of how Rho small GTPase activitie
Externí odkaz:
https://doaj.org/article/96f940d7a0ec4d6eb66092a8c3263bfc
Autor:
Jingnan Zhang, Ze Zhang, Zhenlin Huang, Manlin Li, Fan Yang, Zeqi Wu, Qian Guo, Xiyu Mei, Bin Lu, Changhong Wang, Zhengtao Wang, Lili Ji
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 2990-3007 (2023)
As the most aggressive breast cancer, triple-negative breast cancer (TNBC) is still incurable and very prone to metastasis. The transform growth factor β (TGF-β)-induced epithelial–mesenchymal transition (EMT) is crucially involved in the growth
Externí odkaz:
https://doaj.org/article/d43870b7d264407da28346d8e41f4fdb
Autor:
Tiago M. A. Carvalho, Madelaine Magalì Audero, Maria Raffaella Greco, Marilena Ardone, Teresa Maggi, Rosanna Mallamaci, Barbara Rolando, Silvia Arpicco, Federico Alessandro Ruffinatti, Alessandra Fiorio Pla, Natalia Prevarskaya, Tomas Koltai, Stephan J. Reshkin, Rosa Angela Cardone
Publikováno v:
Cells, Vol 13, Iss 9, p 730 (2024)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with high mortality due to early metastatic dissemination and high chemoresistance. All these factors are favored by its extracellular matrix (ECM)-rich microenvironment, which i
Externí odkaz:
https://doaj.org/article/359ae37a40954942bc5f86182bbda81f
Autor:
Yue Zhao, Xiufeng Xie, Lusong Tian, Fang Liu, Yulin Sun, Haizhen Lu, Xiaohang Zhao, Yousheng Mao
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 3299-3312 (2023)
Abstract Background Emerging evidence indicates that myristoylated alanine‐rich C kinase substrate like 1 (MARCKSL1) is involved in the progression of esophageal squamous cell carcinoma (ESCC). However, the underpinning mechanism is unclear. Here,
Externí odkaz:
https://doaj.org/article/b076d27138c8419a8043574f374b25c4
Akademický článek
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