Zobrazeno 1 - 10
of 879
pro vyhledávání: '"Intrinsically disordered regions"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3143-3154 (2024)
The zinc-finger antiviral protein (ZAP) is an innate immunity sensor of non-self nucleic acids. Its antiviral activity is exerted through the physical interaction with different cofactors, including TRIM25, Riplet and KHNYN. Cellular proteins that in
Externí odkaz:
https://doaj.org/article/6cbd8ca86a4c4d04a12d599b53e23d37
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 322-339 (2024)
Protein aggregation, a consequence of misfolding and impaired proteostasis, can lead to cellular malfunctions such as various proteinopathies. The mechanisms protecting proteins from aggregation in complex cellular environments have long been investi
Externí odkaz:
https://doaj.org/article/636a7a351a044219b211efb88ebe307a
Autor:
Yusuf, Anas a, Usman, Abdurrahman a, Isah, Murtala Bindawa a, d, Dang, Mei a, Zhang, Xiaoying a, b, c, ⁎
Publikováno v:
In Microbiological Research March 2025 292
Publikováno v:
In Protein Expression and Purification March 2025 227
Autor:
Stefano Magnati, Enrico Bracco
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 158-167 (2024)
In the last few decades, the traditional paradigm of teleonomy, in which the amino acid sequence of a protein is tightly associated with its structure and, in turn, with its function, has been partially undermined. The idea of a protein as a two-stat
Externí odkaz:
https://doaj.org/article/0b087316a3174ade84b0ecdb5a46eb10
Autor:
De La Cruz, Nancy 1, 3, Pradhan, Prashant 1, 3, Veettil, Reshma T. 1, 3, Conti, Brooke A. 2, Oppikofer, Mariano 2, Sabari, Benjamin R. 1, 4, ∗
Publikováno v:
In Molecular Cell 19 September 2024 84(18):3497-3512
Publikováno v:
Epigenomes, Vol 8, Iss 3, p 33 (2024)
Proteins are localized and concentrated at cellular and genomic locations for specific and efficient functions. Efforts to understand protein accumulation in eukaryotic organisms have primarily focused on multivalent interactions between intrinsicall
Externí odkaz:
https://doaj.org/article/c7b00d65d115467d8cb824a51a560439
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Intrinsically disordered regions (IDRs) are widely distributed in proteins and related to many important biological functions. Accurately identifying IDRs is of great significance for protein structure and function analysis. Becau
Externí odkaz:
https://doaj.org/article/03754250f9fa47a7bf7d3a64fc9668f8
Autor:
Marco Schiavina, Lorenzo Bracaglia, Tessa Bolognesi, Maria Anna Rodella, Giuseppe Tagliaferro, Angela Sofia Tino, Roberta Pierattelli, Isabella C. Felli
Publikováno v:
Journal of Magnetic Resonance Open, Vol 18, Iss , Pp 100143- (2024)
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) of complex multi-domain proteins are now identified as a trend topic by the scientific community. NMR constitutes a unique investigation tool to access atom resolved
Externí odkaz:
https://doaj.org/article/128b4135755546d79da5e64a2f8be140
Autor:
Ling Cai, Gang Greg Wang
Publikováno v:
Nucleus, Vol 14, Iss 1 (2023)
ABSTRACTThe establishment, maintenance and dynamic regulation of three-dimensional (3D) chromatin structures provide an important means for partitioning of genome into functionally distinctive domains, which helps to define specialized gene expressio
Externí odkaz:
https://doaj.org/article/e540dd65ec1a4afcbcc8a175f94d48c2