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A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice

Autor: Bo Sun, Mingke Ni, Shanshan Tian, Wenting Guo, Shitian Cai, Mads T. Sondergaard, Yongxiang Chen, Yongxin Mu, John P. Estillore, Ruiwu Wang, Ju Chen, Michael T. Overgaard, Michael Fill, Josefina Ramos‐Franco, Mette Nyegaard, Sui Rong Wayne Chen

Publikováno v: Sun, B, Ni, M, Tian, S, Guo, W, Cai, S, Sondergaard, M T, Chen, Y, Mu, Y, Estillore, J P, Wang, R, Chen, J, Overgaard, M T, Fill, M, Ramos-Franco, J, Nyegaard, M & Wayne Chen, S R 2022, ' A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice ', Journal of Cellular Physiology, vol. 237, no. 8, pp. 3305-3316 . https://doi.org/10.1002/jcp.30783
Sun, B, Ni, M, Tian, S, Guo, W, Cai, S, Sondergaard, M T, Chen, Y, Mu, Y, Estillore, J P, Wang, R, Chen, J, Overgaard, M T, Fill, M, Ramos-Franco, J, Nyegaard, M & Wayne Chen, S R 2022, ' A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice ', Journal of cellular physiology, vol. 237, no. 8, pp. 3305-3316 . https://doi.org/10.1002/jcp.30783

Inositol 1,4,5-trisphosphate receptor 1 (ITPR1) is an intracellular Ca2+ release channel critical for numerous cellular processes. Despite its ubiquitous physiological significance, ITPR1 mutations have thus far been linked to primarily movement diso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb7193884eed23c179e780e657a9347
https://pubmed.ncbi.nlm.nih.gov/35621185

Cardiac expression of ryanodine receptor subtype 3; a strategic component in the intracellular Ca2+ release system of Purkinje fibers in large mammalian heart

Autor: Bruno D. Stuyvers, Rebecca E. Daniels, John J. McGuire, Vincenzo Sorrentino, Elizabeth W. Chia, Kazi T. Haq, Masahito Miura, Lawson Miller

Publikováno v: Journal of Molecular and Cellular Cardiology. 104:31-42

Background Three distinct Ca 2 + release channels were identified in dog P-cells: the ryanodine receptor subtype 2 ( RyR2 ) was detected throughout the cell, while the ryanodine receptor subtype 3 ( RyR3 ) and inositol phosphate sensitive Ca 2 + rele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6181675c38fd39e45f8b496f462fc6a
https://doi.org/10.1016/j.yjmcc.2017.01.011

Quantifying Ca2+ signaling and contraction in vascular pericytes and smooth muscle cells

Autor: Christine L. Mummery, Valeria V. Orlova, Oleh V. Halaidych

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, 513(1), 112-118. ACADEMIC PRESS INC ELSEVIER SCIENCE

Vascular pericytes and smooth muscle cells surround many blood vessels of the body. Their primary roles include vessel stabilization and regulation of the blood flow. The high degree of heterogeneity among these cells is dictated by (1) differences i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c7a898328f09bcb4cf11e2035cc0b7

Impact of Janus Kinase 3 on Cellular Ca2+ Release, Store Operated Ca2+ Entry and Na+/Ca2+ Exchanger Activity in Dendritic Cells

Autor: Sabina Honisch, Jing Yan, Zohreh Hosseinzadeh, Joerg Fuchs, Florian Lang, Evi Schmid, Ekaterina Shumilina

Publikováno v: Cellular Physiology and Biochemistry, Vol 36, Iss 6, Pp 2287-2298 (2015)

Background/Aims: Janus kinase 3 (JAK3), a tyrosine kinase mainly expressed in hematopoietic cells, participates in the signaling stimulating cell proliferation. The kinase is expressed in dendritic cells (DCs), antigen presenting cells involved in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b4d1f0fc803bd4574129e7e20c92b9
http://www.karger.com/Article/FullText/430192