Zobrazeno 1 - 10
of 6 818
pro vyhledávání: '"Intracellular Ca2+"'
Autor:
Emi Hiromatsu, Toshifumi Abe, Kwesi Teye, Hiroshi Koga, Norito Ishii, Takahiro Hamada, Takekuni Nakama
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 4, Pp 1227-1230 (2024)
Abstract Transient acantholytic dermatosis (TAD) is a relatively common skin disease that typically affects older individuals, which shows clinical and histologic similarities to autosomal dominant Darier disease. TAD was recently shown to be caused
Externí odkaz:
https://doaj.org/article/8c5f9e64d3ef414ea18723d2abd1247b
Autor:
Lingwei Huang, Yiren Jiao, Hangbin Xia, Huili Li, Jing Yu, Yumei Que, Zhen Zeng, Chen Fan, Chen Wang, Chen Yang, Jiang Chang
Publikováno v:
Journal of Orthopaedic Translation, Vol 48, Iss , Pp 146-155 (2024)
Background: Long-term physical inactivity probably leads to a co-existence of osteoporosis and sarcopenia which result in a high risk of falls, fractures, disability and even mortality. However, universally applicable and feasible approaches are lack
Externí odkaz:
https://doaj.org/article/d9f2a39fc7ee472197bf1b9896b057d6
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-12 (2024)
Abstract Excessive clotting or abnormal platelet accumulation can lead to serious cardiovascular disorders such as atherosclerosis, stroke, and thrombosis. Therefore, it is imperative to identify compounds capable of controlling or impeding platelet
Externí odkaz:
https://doaj.org/article/ddbd1c2732394beea68f785cac7f2c9a
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 6, Pp 706-713 (2023)
Background and objective: The ability to inhibit aggregation has been demonstrated with synthetically derived ginsenoside compounds G-Rp (1, 3, and 4) and ginsenosides naturally found in Panax ginseng 20(S)-Rg3, Rg6, F4, and Ro. Among these compounds
Externí odkaz:
https://doaj.org/article/68434cbe2631411ca5a9f6f35b7ead98
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1135 (2024)
Fine particulate matter (PM2.5) is a significant cause of respiratory diseases and associated cellular damage. The mechanisms behind this damage have not been fully explained. This study investigated two types of cellular damage (inflammation and pyr
Externí odkaz:
https://doaj.org/article/18eb013d37ff448094b23bf09814f960
Autor:
Claudia M. Lucero, Laura Navarro, Cristián Barros-Osorio, Patricio Cáceres-Conejeros, Juan A. Orellana, Gonzalo I. Gómez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Chronic kidney disease (CKD) is a prevalent health concern associated with various pathological conditions, including hypertensive nephropathy. Mesangial cells are crucial in maintaining glomerular function, yet their involvement in CKD pathogenesis
Externí odkaz:
https://doaj.org/article/e4c68d29d50c4fca9a92c2095aea4f94
Autor:
Miyesaier Abudureyimu, Xuanming Luo, Lingling Jiang, Xuejuan Jin, Cuizhen Pan, Wei Yu, Junbo Ge, Yingmei Zhang, Jun Ren
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103081- (2024)
Aims: Heart failure with preserved ejection fraction (HFpEF) is a devastating health issue although limited knowledge is available for its pathogenesis and therapeutics. Given the perceived involvement of mitochondrial dysfunction in HFpEF, this stud
Externí odkaz:
https://doaj.org/article/9ecf59cd6edc4cd6956426af92af67d3
Autor:
Kyung-A Byun, Je Hyuk Lee, So Young Lee, Seyeon Oh, Sosorburam Batsukh, Gwahn-woo Cheon, Dongun Lee, Jeong Hee Hong, Kuk Hui Son, Kyunghee Byun
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7232 (2024)
Poly L-lactic acid (PLLA) fillers stimulate collagen synthesis by activating various immune cells and fibroblasts. Piezo1, an ion channel, responds to mechanical stimuli, including changes in extracellular matrix stiffness, by mediating Ca2+ influx.
Externí odkaz:
https://doaj.org/article/3e49b168a44b4e16a70e7bb1079568f1
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The suprachiasmatic nucleus (SCN) of the hypothalamus is the master circadian clock in mammals. SCN neurons exhibit circadian Ca2+ rhythms in the cytosol, which is thought to act as a messenger linking the transcriptional/translational feedback loop
Externí odkaz:
https://doaj.org/article/4353d4f442174b4bac08cb347957a54c
Autor:
Shunit Neeman-Egozi, Ido Livneh, Irit Dolgopyat, Udi Nussinovitch, Helena Milman, Nadav Cohen, Binyamin Eisen, Aaron Ciechanover, Ofer Binah
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4932 (2024)
The ubiquitin–proteasome system (UPS) is an essential mechanism responsible for the selective degradation of substrate proteins via their conjugation with ubiquitin. Since cardiomyocytes have very limited self-renewal capacity, as they are prone to
Externí odkaz:
https://doaj.org/article/3b1ff9ecfa7d43ff81bb3fabd8fc1e91