Intra-Amniotic Delivery of CRMP4 siRNA Improves Mesenchymal Stem Cell Therapy in a Rat Spina Bifida Model

Autor: Hui Gu, Wenting Luo, Weilin Wang, Dan Liu, Chaonan Zhang, Wei Ma, Yuzuo Bai, Xiaowei Wei, Songying Cao, Zhengwei Yuan

Publikováno v: Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 20, Iss, Pp 502-517 (2020)

Neural tube defects (NTDs) result in prenatal mortality and lifelong morbidity, and available treatments have limited efficacy. We previously suggested that prenatal bone marrow-derived mesenchymal stem cell (BMSC) transplantation could treat neuron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363cc3c4d89d6e9c97c30610dcbed1e6
http://europepmc.org/articles/PMC7177192

Intra-amniotic Injection of Mouse Embryos

Autor: Peng Zou, Jiayi Zhang, Liyuan Cui, Lu Lu, Qingshuo Meng

Publikováno v: Bio Protoc

Recent outbreaks of infectious neuro-developmental diseases such as congenital Zika syndrome - have led to a demand for prognosis data from animal models. We developed an intra-amniotic injection mice model that allows Zika virus (ZIKV) infected mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81354166647137075be618a2706ff823
https://doi.org/10.21769/bioprotoc.2854

521: Intra-amniotic injection alters the intrauterine microbiome in a primate model of inflammatory preterm birth

Autor: Alan H. Jobe, Lisa M. Soederberg Miller, Derrick M. Chu, Amanda Prince, Kjersti Aagaard, Jun Ma, Claire A. Chougnet, Min Hu, Suhas G. Kallapur

Publikováno v: American Journal of Obstetrics and Gynecology. 220:S349

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e74a03034fb3a15b3888827eb020b9a3
https://doi.org/10.1016/j.ajog.2018.11.543

Prenatal Therapy in Developmental Disorders: Drug Targeting via Intra-Amniotic Injection to Treat X-Linked Hypohidrotic Ectodermal Dysplasia

Autor: Katharina Hermes, AnhThu Dang, Pascal Schneider, Kenneth M. Huttner, Holm Schneider, Peter Krieg

Publikováno v: The Journal of investigative dermatology
Orphanet Journal of Rare Diseases
Journal of Investigative Dermatology, vol. 134, no. 12, pp. 2985-2987

Background Disorders that irremediably affect fetuses make early stage therapies desirable. X-linked hypohidrotic ectodermal dysplasia (XLHED), the most common inherited disorder of ectoderm development affecting the skin and its appendages, glands,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02082172a5fd7c5c5b18c87a2e90761d

Transvaginal intra-amniotic injection of methotrexate in early ectopic pregnancy. Advantages over the laparoscopic approach

Autor: J. Tzafettas, J. Bondis, V. Zournatzi, S. Anapliotis, N. Oxouzoglou, A. Boucklis

Publikováno v: Early Human Development. 39:101-107

Methotrexate (MTX, 100 mg) was administered to 36 patients with early ectopic pregnancy locally, either under laparoscopic control into the distended fallopian tube (group A, n = 16), or transvaginally into the gestational sac directly, under ultraso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc983b892336bb1430f6aa6ec074f1d
https://doi.org/10.1016/0378-3782(94)90159-7