Zobrazeno 1 - 10
of 1 402
pro vyhledávání: '"Intestinal stem cell"'
Autor:
Hisako Kayama, Kiyoshi Takeda
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-18 (2024)
Abstract The gastrointestinal tract harbors diverse microorganisms in the lumen. Epithelial cells segregate the luminal microorganisms from immune cells in the lamina propria by constructing chemical and physical barriers through the production of va
Externí odkaz:
https://doaj.org/article/03be204e404a48e2b855c972701c18ba
Autor:
Luo H, Guo M, Li M, Zhao Y, Shen J, Du F, Chen Y, Deng S, Sun Y, Gu L, Li W, Li X, Chen M, Xiao Z, Wang S, Wu X
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 6023-6038 (2024)
Haoming Luo,1,2,* Miao Guo,3,4,* Mingxing Li,1 Yueshui Zhao,1 Jing Shen,1 Fukuan Du,1 Yu Chen,1 Shuai Deng,1 Yuhong Sun,1 Li Gu,1 Wanping Li,1 Xiaobing Li,1 Meijuan Chen,1 Zhangang Xiao,1,5,6 Shengpeng Wang,3,4 Xu Wu1,7 1Cell Therapy & Cell D
Externí odkaz:
https://doaj.org/article/025c00d7c135496a8733075c17a85a32
Autor:
Michael J. Cotton, Pablo Ariel, Kaiwen Chen, Vanessa A. Walcott, Michelle Dixit, Keith A. Breau, Caroline M. Hinesley, Katarzyna M. Kedziora, Cynthia Y. Tang, Anna Zheng, Scott T. Magness, Joseph Burclaff
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The intestinal epithelium dynamically controls cell cycle, yet no experimental platform exists for directly analyzing cell cycle phases in non-immortalized human intestinal epithelial cells (IECs). Here, we present two reporters and a comple
Externí odkaz:
https://doaj.org/article/2166ab0898f7409294e33d7ee9771520
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionIntestinal stem cells (ISCs) are crucial for tissue repair and homeostasis because of their ability to self-renew and differentiate. However, their functionality declines significantly with age, resulting in reduced tissue regeneration an
Externí odkaz:
https://doaj.org/article/93e5c757b0f742849faa6c2c88b72020
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Genetically lean and obese individuals have distinct intestinal microbiota and function. However, the underlying mechanisms of the microbiome heterogeneity and its regulation on epithelial function such as intestinal stem cell (ISC) fate rem
Externí odkaz:
https://doaj.org/article/fb34ec33c33f451ebfb67f038f5b14ec
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Mammalian intestinal epithelium constantly undergoes rapid self-renewal and regeneration sustained by intestinal stem cells (ISCs) within crypts. Inducible nitric oxide synthase (iNOS) is an important regulator in tissue homeostas
Externí odkaz:
https://doaj.org/article/066057cc6e29460baa3dd3342af39295
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTIntestinal stem cells (ISCs) are critical for the development and rapid turnover of intestinal epithelium. The regulatory effects of gut microbiota and their metabolites on ISCs stemness remain elusive. Fucose has been demonstrated to mediate
Externí odkaz:
https://doaj.org/article/008cd7f8c54841a49284ddff030cc00c
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 4, Pp 351-356 (2023)
Objective To investigate the effects of Akkermansia muciniphila (AKK) on azomethane-oxide (AOM)/glucan sodium sulfate (DSS)-induced inflammatory colorectal cancer mouse model and intestinal stem cells. Methods AOM/DSS-induced mouse models of inflamma
Externí odkaz:
https://doaj.org/article/03d93764893c4e4e89c3d90fb0fb1874
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 668 (2024)
Intestinal epithelial cell activities during homeostasis and regeneration are well described, but their potential interactions with stromal cells remain unresolved. Exploring the functions of these heterogeneous intestinal mesenchymal stromal cells (
Externí odkaz:
https://doaj.org/article/3c246d18913d4b52b4948d357bb2764a
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 264, Iss , Pp 115457- (2023)
Deoxynivalenol (DON) is a common toxin in grains and feeds, and DON exposure triggers severe small intestinal injury and inflammation, which harms the health of humans and livestock. DON treatment leads to a decrease in Paneth cells, whereas the role
Externí odkaz:
https://doaj.org/article/db1de6936c2a4b819a11979266e67d77