Zobrazeno 1 - 10
of 417
pro vyhledávání: '"Intestinal organoid"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The regeneration of epithelia is crucial for maintaining intestinal homeostasis. Irisin is an exercise-induced hormone originally found to be secreted by skeletal muscles, thereby regulating energy metabolism. Recent studies have revealed th
Externí odkaz:
https://doaj.org/article/38ea23c0fc8c442aabb2c97da7135a0c
Autor:
Hana Lee, Seunghye Yang, Kyung Jin Lee, Si-Na Kim, Ji-Seon Jeong, Ki Young Kim, Cho-Rok Jung, Sooyeon Jeon, Dayeon Kwon, Sungin Lee, Hanbyeol Lee, Chihye Park, Sun-Ju Ahn, Jongman Yoo, Mi-Young Son
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
To enhance the practical application of intestinal organoids, it is imperative to establish standardized guidelines. This proposed standardization outlines a comprehensive framework to ensure consistency and reliability in the development, characteri
Externí odkaz:
https://doaj.org/article/6f8429ed52b1417d9369cf32af300863
Autor:
Junxuan Peng, Shengda Cao, Zhen Hu, Jiayi Zhu, Yi Zhu, Xiaole Sheng, Zuchao Cai, Rongpan Bai, Xushen Xiong, Jinghao Sheng
Publikováno v:
Environment International, Vol 191, Iss , Pp 108948- (2024)
Bisphenol A (BPA) and its substitute fluorene-9-bisphenol (BHPF) are used in consumer products; however, their toxic effects on intestinal epithelium remain largely unknown. In this study, we combined intestinal organoids and single-cell RNA sequenci
Externí odkaz:
https://doaj.org/article/9c16797344c44056b0d5ac1e2b937b68
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract In the past decade, intestinal organoid technology has paved the way for reproducing tissue or organ morphogenesis during intestinal physiological processes in vitro and studying the pathogenesis of various intestinal diseases. Intestinal or
Externí odkaz:
https://doaj.org/article/48ad5d4b0b8347aa8aeb0142cd015df6
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 39, Iss 1, Pp 2-11 (2024)
Background: The small intestine plays a crucial role in animals in maintaining homeostasis as well as a series of physiological events such as nutrient uptake and immune function to improve productivity. Research on intestinal organoids has recently
Externí odkaz:
https://doaj.org/article/f0b0287ba9eb4e6bb781ad7928293176
Autor:
Ryoma Endo, Shinya Sugimoto, Koji Shirosaki, Hirochika Kato, Motoshi Wada, Takanori Kanai, Toshiro Sato
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 64-73 (2023)
Short bowel syndrome (SBS) is a rare condition, the main symptom of which is malabsorption following extensive resection of the small intestine. Treatment for SBS is mainly supportive, consisting of supplementation, prevention and treatment of compli
Externí odkaz:
https://doaj.org/article/cd8e24d28cfb439fbb6698316c9461f0
Publikováno v:
陆军军医大学学报, Vol 45, Iss 21, Pp 2195-2205 (2023)
Objective To investigate the regulatory effect of nobiletin (NOB) at typical effective doses on intestinal stem cells in vivo and in vitro. Methods After a 3D culture model of mouse colorectal tumor cell line MC38 was constructed, the death and survi
Externí odkaz:
https://doaj.org/article/27559199d3dc444087d8a262f0ab5d78
Publikováno v:
Organoids, Vol 2, Iss 3, Pp 156-164 (2023)
We evaluated the redox status, precisely glutathione levels, which have a major impact in cellular detoxification and antioxidant defence in IBD-derived and healthy intestinal organoids. Therefore, we wanted to explore the differences in terms of the
Externí odkaz:
https://doaj.org/article/105032b36f4d40369aa9b756e02c4459
Autor:
Ahed Almalla, Nadra Alzain, Laura Elomaa, Fiona Richter, Johanna Scholz, Marcus Lindner, Britta Siegmund, Marie Weinhart
Publikováno v:
Cells, Vol 13, Iss 13, p 1080 (2024)
The luminal surface of the intestinal epithelium is protected by a vital mucus layer, which is essential for lubrication, hydration, and fostering symbiotic bacterial relationships. Replicating and studying this complex mucus structure in vitro prese
Externí odkaz:
https://doaj.org/article/c5354b1e41ae4d7cb521d530c0600222
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract A healthy intestine plays an important role in the growth and development of farm animals. In small intestine, Paneth cells are well known for their regulation of intestinal microbiota and intestinal stem cells (ISCs). Although there has bee
Externí odkaz:
https://doaj.org/article/b366e6fcf4494cab80efd2ae1f92ea76