Zobrazeno 1 - 10
of 9 286
pro vyhledávání: '"Intestinal Epithelial Cells"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 3876-3900 (2024)
Despite the promising prospects of nanoparticles in oral drug delivery, the process of oral administration involves a complex transportation pathway that includes cellular uptake, intracellular trafficking, and exocytosis by intestinal epithelial cel
Externí odkaz:
https://doaj.org/article/6d57b9d6f6db408caad858238c51529b
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundAging can impair the ability of elderly individuals to fight infections and trigger persistent systemic inflammation, a condition known as inflammaging. However, the mechanisms underlying the development of inflammaging remain unknown.Metho
Externí odkaz:
https://doaj.org/article/0a8c4a01ace4467e83bbca86f8c4264d
Autor:
Neil A. Mabbott, Koji Hase
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/017f85d2374c43aca733b51bc29c55cc
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Ferroptosis is a type of regulated cell death that occurs due to the iron-dependent accumulation of lethal reactive oxygen species (ROS) from lipids. Ferroptosis is characterized by distinct morphological, biochemical, and genetic features that diffe
Externí odkaz:
https://doaj.org/article/5df305e7e340432aab9f9b23e2476d22
Autor:
Mingyang Cheng, Bin Xu, Yu Sun, Junhong Wang, Yiyuan Lu, Chunwei Shi, Tianxu Pan, Wenhui Zhao, Xiaoxu Li, Xiaomei Song, Jianzhong Wang, Nan Wang, Wentao Yang, Yanlong Jiang, Haibin Huang, Guilian Yang, Yan Zeng, Dongqin Yang, Chunfeng Wang, Xin Cao
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT E3 ubiquitin ligase (E3) plays a vital role in regulating inflammatory responses by mediating ubiquitination. Previous studies have shown that ankyrin repeat and SOCS box-containing protein 3 (ASB3) is involved in immunomodulatory functions
Externí odkaz:
https://doaj.org/article/662847224e4346f8b9c399c0b2d5785d
Autor:
Zichen Wang, Jun Shen
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The prevalence of Crohn’s disease (CD), a subtype of inflammatory bowel disease (IBD), is increasing worldwide. The pathogenesis of CD is hypothesized to be related to environmental, genetic, immunological, and bacterial factors. Current s
Externí odkaz:
https://doaj.org/article/562fbd66665642bf92adb8a7f30892a9
Autor:
Juanjuan Zhao, Mengmeng Guo, Yaping Yan, Ya Wang, Xu Zhao, Jing Yang, Jing Chen, Chao Chen, Lin Tang, Wenhuan Zeng, Yiting Liu, Ming Qin, Ya Zhou, Lin Xu
Publikováno v:
Journal of Advanced Research, Vol 57, Iss , Pp 119-134 (2024)
Introduction: The epithelial immunomodulation and regeneration are intrinsic critical events against inflammatory bowel disease (IBD). MiR-7 is well documented as a promising regulator in the development of various diseases including inflammatory dis
Externí odkaz:
https://doaj.org/article/352656930e774bea8008e26c627c15ad
Autor:
Anandi Rajan, Pablo Gallego, Brendan Dolan, Piyush Patel, Chinmay Dwibedi, Ana S. Luis, Sergio Trillo-Muyo, Liisa Arike, Sjoerd van der Post, Magnus Simrén, Thaher Pelaseyed
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The anaerobic spirochete Brachyspira causes intestinal spirochetosis, characterized by the intimate attachment of bacterial cells to the colonic mucosa, potentially leading to symptoms such as diarrhea, abdominal pain, and weight loss. Despite the cl
Externí odkaz:
https://doaj.org/article/8912f417e26447cc988a1fa5ed44a469
Autor:
Shangshu Nie, Zhongchao Zhang, Yudong Ji, Qiang Ding, Jin Gong, Fang Xiao, Liping Chen, Dean Tian, Mei Liu, Zhenlong Luo
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut microbiota-derived extracellular vesicles (mEVs) are reported to regulate inflammatory response by delivering bacterial products into host cells. The complement receptor of the immunoglobulin superfamily macrophages (CRIg+ Mφ) could clear invadi
Externí odkaz:
https://doaj.org/article/7ea1a813fae04ecb8781609eb5040763
Autor:
Lang Chen, Hongwei Yi, Qingtian Li, Tianhao Duan, Xin Liu, Linfeng Li, Helen Y. Wang, Changsheng Xing, Rong‐Fu Wang
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract T‐bet, encoded by TBX21, is extensively expressed across various immune cell types, and orchestrates critical functions in their development, survival, and physiological activities. However, the role of T‐bet in non‐immune compartments
Externí odkaz:
https://doaj.org/article/2f77424b65084d95aa8bcb444d0e19c5