Zobrazeno 1 - 10
of 603
pro vyhledávání: '"Intervertebral disk degeneration"'
Autor:
Si‐Ping Zhang, Min Tong, Shi‐Da Li, Bin Zhang, Wenhao Zhang, Rong Wang, Zhen‐Yu Dong, Yi‐Fei Huang
Publikováno v:
Orthopaedic Surgery, Vol 16, Iss 11, Pp 2587-2597 (2024)
Microvascular changes are considered key factors in the process of intervertebral disk degeneration (IDD). Microvascular invasion and growth into the nucleus pulposus (NP) and cartilaginous endplates are unfavorable factors that trigger IDD. In contr
Externí odkaz:
https://doaj.org/article/593106ec5d794e16b582d27f1129d7b2
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Objective The purpose of this study is to use two-sample Mendelian randomization (MR) to investigate the causal relationship between skin microbiota, especially Propionibacterium acnes, and intervertebral disc degeneration (IVDD), low back p
Externí odkaz:
https://doaj.org/article/1a4b59f41a7f4ce1b95c895041776334
Autor:
Imke Rudnik-Jansen, Jie Du, Nina Karssemakers-Degen, Anna R. Tellegen, Parvesh Wadhwani, Daniele Zuncheddu, Björn P. Meij, Jens Thies, Pieter Emans, Fetullah C. Öner, George Mihov, Joao Pedro Garcia, Anne S. Ulrich, Sibylle Grad, Marianna A. Tryfonidou, Hugo van Ingen, Laura B. Creemers
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Intradiscal drug delivery is a promising strategy for treating intervertebral disk degeneration (IVDD). Local degenerative processes and intrinsically low fluid exchange are likely to influence drug retention. Understanding their connection will enab
Externí odkaz:
https://doaj.org/article/e74ff26b3ae344bf99b69a5fc7b3d7c3
Autor:
Kaizhong Wang, Xiangyan Liu, Huagui Huang, Moran Suo, Jinzuo Wang, Xin Liu, Jing Zhang, Xin Chen, Zhonghai Li
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Intervertebral disk degeneration (IDD) is a common clinical spinal disease and one of the main causes of low back pain (LBP). Generally speaking, IDD is considered a natural degenerative process with age. However, with the deepening of research, peop
Externí odkaz:
https://doaj.org/article/b50d14b676ba4eb3a2a3bf7863063a66
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundIntervertebral disk degeneration (IVDD) is a complex degenerative skeletal condition, potentially influenced by micronutrients and serum metabolites in its etiology. However, the exact causal relationship between these factors and IVDD rema
Externí odkaz:
https://doaj.org/article/12a509f6c32a4db691ddafc71109b4a3
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
ObjectiveThis study aimed to discover micro-ribonucleic acids (microRNAs) involved in the degeneration of cartilage endplates through next-generation sequencing and lay the foundation for further research.MethodsThe cartilage endplate was obtained fr
Externí odkaz:
https://doaj.org/article/d85bfe33d1494e22bf24b7e119a87b30
Autor:
Ding-Qiang Chen, Zhi-Qiang Que, Wen-Bin Xu, Ke-Yi Xiao, Nai-Kun Sun, Hong-Yu Song, Jin-Yi Feng, Guang-Xun Lin, Gang Rui
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundWhile intervertebral disc degeneration (IVDD) is crucial in numerous spinally related illnesses and is common among the elderly, the complete understanding of its pathogenic mechanisms is still an area of ongoing study. In recent years, it
Externí odkaz:
https://doaj.org/article/4406593d46074b7da118621aad08f28d
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Purpose Lower back pain (LBP), mainly caused by intervertebral disk (IVD) degeneration (IDD), is widely prevalent worldwide and is a serious socioeconomic burden. Numerous factors may trigger this degenerative process, and microbial dysbiosi
Externí odkaz:
https://doaj.org/article/24ca55d2b4eb49c9867bc2ea05926550
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract Objective To explore the potential mechanism of Yougui Wan on deformed lumbar intervertebral disk structure in rats. Methods Thirty male Sprague–Dawley rats were randomly divided into 3 groups, with 10 rats in each group. The animals in th
Externí odkaz:
https://doaj.org/article/10c7c50457da44e9b88f652dade46957
Publikováno v:
JOR Spine, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Background Intervertebral disk degeneration (IVDD) is a common spine disease, and inflammation is considered to be one of its main pathogenesis. Apigetrin (API) is a natural bioactive flavonoid isolated from various herbal medicines and show
Externí odkaz:
https://doaj.org/article/d60361eafed44d1e869455be7b913998