Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Interphase Chromosome"'
Publikováno v:
Environmental Advances, Vol 9, Iss , Pp 100265- (2022)
Radiological /nuclear (R/N) mass casualty incidents can potentially expose several hundreds and thousands of humans to substantial doses of ionizing radiation (IR). Timely assessment of radiation dose is critical for making “life-saving” clinical
Externí odkaz:
https://doaj.org/article/f32c33ae3c5a4108ae3dd9bca5e596a0
Autor:
Michael Elbaum, Herbert G. Kasler, John W. Sedat, Hu Cang, Cornelis Murre, Angus McDonald, Eric Verdin, Muthuvel Arigovindan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 20
A molecular architecture is proposed for an example mitotic chromosome, human Chromosome 10. This architecture is built on a previously described interphase chromosome structure based on Cryo-EM cellular tomography (1), thus unifying chromosome struc
Publikováno v:
Journal of Experimental Botany. 71:6262-6272
Despite much recent progress, our understanding of the principles of plant genome organization and its dynamics in three-dimensional space of interphase nuclei remains surprisingly limited. Notably, it is not clear how these processes could be affect
Autor:
Moneeb A.K. Othman, Amelie Lier, Susann Junker, Philipp Kempf, Franziska Dorka, Erich Gebhart, Frenny J. Sheth, Beata Grygalewicz, Samarth Bhatt, Anja Weise, Kristin Mrasek, Thomas Liehr, Marina Manvelyan
Publikováno v:
BioDiscovery, Vol 4, Iss , Pp 1-5 (2012)
The impact of chromosome architecture in the formation of chromosome aberrations is a recent finding of interphase directed molecular cytogenetic studies. There evidence was provided that disease specific chromosomal translocations could be due to ti
Externí odkaz:
https://doaj.org/article/513c70f80b3b441ab4176526fb9207aa
Autor:
Ivan Y. Iourov
Publikováno v:
BioDiscovery, Vol 4, Iss , Pp 1-5 (2012)
The last hierarchical level of cellular genome organization is the spatial arrangement of chromosomes within the nuclear space. Despite of high regulatory potential and functional implications, issues concerning nuclear organization at chromosomal le
Externí odkaz:
https://doaj.org/article/bce532a3005645dbbf362fb30de39ac6
Akademický článek
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Autor:
Cornelis Murre, Joseph S. Lucas, Angus McDonald, Zvi Kam, John W. Sedat, Hu Cang, Michael Elbaum, Muthuvel Arigovindan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 26
Cryoelectron tomography of the cell nucleus using scanning transmission electron microscopy and deconvolution processing technology has highlighted a large-scale, 100- to 300-nm interphase chromosome structure, which is present throughout the nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ce05fc30a3a9b606872dfbe4814a8b
https://doi.org/10.1101/2021.10.08.463051
https://doi.org/10.1101/2021.10.08.463051
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 108(2)
Arabidopsis thaliana (arabidopsis) has become a major plant research model where interphase nuclear organization exhibits unique features, including nucleolus-associated telomere clustering. The chromocenter (CC)-loop model, or rosette-like configura
Autor:
D. Thirumalai, Guang Shi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Nature Communications
Hi-C experiments are used to infer the contact probabilities between loci separated by varying genome lengths. Contact probability should decrease as the spatial distance between two loci increases. However, studies comparing Hi-C and FISH data show
Autor:
Ardalan Naseri, Shaojie Zhang, Thoru Pederson, David Grunwald, Li-Chun Tu, Hanhui Ma, Yu-Chieh Chung
Publikováno v:
The Journal of Cell Biology
Ma et al. use the CRISPR-Sirius system to track the dynamics of genomic loci situated kilobases to megabases apart on a single chromosome throughout the cell cycle, providing insight into the compaction–relaxation dynamics of the interphase chromos