Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Interneurons/drug effects"'
Publikováno v:
Mańko, M, Geracitano, R & Capogna, M 2011, ' Functional connectivity of the main intercalated nucleus of the mouse amygdala ', The Journal of Physiology, vol. 589, no. Pt 8, pp. 1911-25 . https://doi.org/10.1113/jphysiol.2010.201475
Intercalated cells (ITCs) of the amygdala are clusters of GABAergic cells that surround the basolateral complex of the amygdala (BLA). Growing evidence suggests that ITCs are required for the expression of fear extinction. The main intercalated nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::79ef680156a4d93172f16159eb9deaef
https://doi.org/10.1113/jphysiol.2010.201475
https://doi.org/10.1113/jphysiol.2010.201475
Autor:
Matthew Brown, Uwe Rudolph, Kelly R. Tan, Cédric Yvon, Jean-Marc Fritschy, Cyril Creton, Christian Lüscher, Gwenaël Labouèbe
Publikováno v:
Nature, Vol. 463, No 7282 (2010) pp. 769-774
Nature
Nature
Benzodiazepines are widely used in clinics and for recreational purposes, but will lead to addiction in vulnerable individuals. Addictive drugs increase the levels of dopamine and also trigger long-lasting synaptic adaptations in the mesolimbic rewar
Autor:
Elli Leppä, Peer Wulff, Waltraud Ogris, Marco Capogna, Peter Somogyi, H. Hoeger, Esa R. Korpi, Anni-Maija Linden, William Wisden, Werner Sieghart, A. Oberto, C. Halbsguth, Theofanis Karayannis, D. W. Cope, Francesco Ferraguti
Publikováno v:
Cope, D W, Halbsguth, C, Karayannis, T, Wulff, P, Ferraguti, F, Hoeger, H, Leppä, E, Linden, A-M, Oberto, A, Ogris, W, Korpi, E R, Sieghart, W, Somogyi, P, Wisden, W & Capogna, M 2005, ' Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation ', The European journal of neuroscience, vol. 21, no. 11, pp. 3002-16 . https://doi.org/10.1111/j.1460-9568.2005.04127.x
Europe PubMed Central
Europe PubMed Central
Zolpidem is a hypnotic benzodiazepine site agonist with some gamma-aminobutyric acid (GABA)(A) receptor subtype selectivity. Here, we have tested the effects of zolpidem on the hippocampus of gamma2 subunit (gamma2F77I) point mutant mice. Analysis of
Publikováno v:
Anesthesiology, Vol. 102, No 5 (2005) pp. 970-976
Background Recent laboratory studies showed that exposure to supraclinical concentrations of propofol can induce cell death of immature neurons. However, no data are available regarding the effects of clinically relevant concentrations of this agent
Action of tachykinins in the hippocampus: facilitation of inhibitory drive to GABAergic interneurons
Publikováno v:
Neuroscience, Vol. 156, No 3 (2008) pp. 527-36
By acting on neurokinin 1 (NK1) receptors, neuropeptides of the tachykinin family can powerfully excite rat hippocampal GABAergic interneurons located in the CA1 region and by this way indirectly inhibit CA1 pyramidal neurons. In addition to contact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92054f57903cbffc2fe46ef8d18992fe
https://archive-ouverte.unige.ch/unige:1687
https://archive-ouverte.unige.ch/unige:1687
Publikováno v:
Elfant, D, Pál, B Z, Emptage, N & Capogna, M 2008, ' Specific inhibitory synapses shift the balance from feedforward to feedback inhibition of hippocampal CA1 pyramidal cells ', The European journal of neuroscience, vol. 27, no. 1, pp. 104-13 . https://doi.org/10.1111/j.1460-9568.2007.06001.x
Feedforward and feedback inhibition are two fundamental modes of operation widespread in the nervous system. We have functionally identified synaptic connections between rat CA1 hippocampal interneurons of the stratum oriens (SO) and interneurons of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::53cea25904a0f8bf3582b38d27192eab
Autor:
Kerr, A, Capogna, M
Publikováno v:
Kerr, A M & Capogna, M 2007, ' Unitary IPSPs enhance hilar mossy cell gain in the rat hippocampus ', The Journal of Physiology, vol. 578, no. Pt 2, pp. 451-70 . https://doi.org/10.1113/jphysiol.2006.121608
Mechanisms that control neuronal gain allow for adaptive rescaling to synaptic inputs of varying strengths or frequencies. Here, we show that unitary IPSPs (uIPSPs) modulate gain and unitary EPSP (uEPSP)-action potential coupling in mossy cells (MCs)
Publikováno v:
Price, C J, Karayannis, T, Pál, B Z & Capogna, M 2005, ' Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare ', Neuropharmacology, vol. 49 Suppl 1, pp. 45-56 . https://doi.org/10.1016/j.neuropharm.2005.05.009
We have studied the effects of groups II and III metabotropic glutamate receptor (mGluR) activation on excitatory responses recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare (SLM). Excitatory postsynaptic currents (EPSCs) evo
Autor:
Ogier, R., Raggenbass, Mario
Publikováno v:
European Journal of Neuroscience, Vol. 17, No 12 (2003) pp. 2639-2647
Substance P and other neuropeptides of the tachykinin family can powerfully excite CA1 hippocampal interneurons present in the CA1 region. In the present work we show that, by exciting hippocampal interneurons, tachykinins can indirectly inhibit pyra
Autor:
Dominique Muller, Sophie Hulo
Publikováno v:
Neuroreport, Vol. 12, No 7 (2001) pp. 1351-1354
Nicotine modulates excitatory and inhibitory transmission in the hippocampus by acting on receptors located on various cellular compartments. We report that nicotine, applied for 5-10 min at concentrations similar to those found during smoking (0.5-5