Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Interneuron migration"'
Autor:
Ting Zhao, Cheng‐Qing Huang, Yi‐Hao Zhang, Yan‐Yan Zhu, Xiao‐Xi Chen, Tao Wang, Jing Shao, Xiu‐Hong Meng, Yichao Huang, Hua Wang, Hui‐Li Wang, Bo Wang, De‐Xiang Xu
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder, characterized by social communication disability and stereotypic behavior. This study aims to investigate the impact of prenatal exposure to 1‐nitropyrene (1‐NP), a key com
Externí odkaz:
https://doaj.org/article/47ca0c4d19604e6da79920e2b41427d6
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Polysialic acid (polySia) is a sugar homopolymer consisting of at least eight glycosidically linked sialic acid units. It is a posttranslational modification of a limited number of proteins with the neural cell adhesion molecule NCAM being the most p
Externí odkaz:
https://doaj.org/article/df30f55e7a38409a8ce91c2552e4abe3
Autor:
Florent Marguet, Gaëlle Friocourt, Mélanie Brosolo, Fanny Sauvestre, Pascale Marcorelles, Céline Lesueur, Stéphane Marret, Bruno J. Gonzalez, Annie Laquerrière
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-18 (2020)
Abstract Alcohol affects multiple neurotransmitter systems, notably the GABAergic system and has been recognised for a long time as particularly damaging during critical stages of brain development. Nevertheless, data from the literature are most oft
Externí odkaz:
https://doaj.org/article/a5d8bc55a1d04ab0bee1d4b0d9ca9fcb
Autor:
Francesco Di Matteo, Fabrizia Pipicelli, Christina Kyrousi, Isabella Tovecci, Eduardo Penna, Marianna Crispino, Angela Chambery, Rosita Russo, Ane Cristina Ayo‐Martin, Martina Giordano, Anke Hoffmann, Emilio Ciusani, Laura Canafoglia, Magdalena Götz, Rossella Di Giaimo, Silvia Cappello
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 6, Pp n/a-n/a (2020)
Abstract Progressive myoclonus epilepsy (PME) of Unverricht–Lundborg type (EPM1) is an autosomal recessive neurodegenerative disorder with the highest incidence of PME worldwide. Mutations in the gene encoding cystatin B (CSTB) are the primary gene
Externí odkaz:
https://doaj.org/article/d7924a20df5e4060b7e35a5b2deeec27
Akademický článek
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Autor:
Ali Ozgur Argunsah, Theofanis Karayannis, Olivia Hanley, Rahel Kastli, George Kanatouris, Elianne Grietje Theodora van der Valk, Tevye J. Stachniak
Publikováno v:
Journal of Neuroscience
The Journal of Neuroscience
The Journal of Neuroscience
Throughout development, neuronal identity is controlled by key transcription factors that determine the unique properties of a cell. During embryogenesis, the transcription factor Prox1 regulates VIP-positive cortical interneuron migration, survival,
Autor:
Sunanjay Bajaj, Sakurako Nagumo Wong, Julie Lévi-Strauss, Joshua A. Bagley, Juergen A. Knoblich, Ábel Vértesy, Veronica Krenn, Christoph Sommer
Publikováno v:
EMBO J
Inhibitory GABAergic interneurons migrate over long distances from their extracortical origin into the developing cortex. In humans, this process is uniquely slow and prolonged, and it is unclear whether guidance cues unique to humans govern the vari
Autor:
Jugajyoti Baruah, Yong Kee Choi, Sivan Subburaju, Abdallah Elkhal, Sarah Kaye, Sangmi Chung, Yeqi Nian, Jahan Khalili, Debkanya Datta, Anju Vasudevan
Publikováno v:
Molecular Psychiatry
Abnormalities of or reductions in GABAergic interneurons are implicated in the pathology of severe neuropsychiatric disorders, for which effective treatments are still elusive. Transplantation of human stem cell-derived interneurons is a promising ce
Autor:
Walter Lichtensteiger, Hubert Rehrauer, Jesús A.F. Tresguerres, Catherine Bassetti-Gaille, Margret Schlumpf, Jelena Kühn Georgijevic
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
Endocrine disrupting chemicals (EDCs) can impair hippocampus-dependent behaviors in rat offspring and in children. In search for key processes underlying this effect, we compared the transcriptomes of rat hippocampus on postnatal day 6 after gestatio