Zobrazeno 1 - 10
of 777
pro vyhledávání: '"Intermediate mesoderm"'
Autor:
Esmeralda Magro-Lopez, Elena Vazquez-Alejo, María de la Sierra Espinar-Buitrago, María Ángeles Muñoz-Fernández
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Several differentiation protocols have enabled the generation of intermediate mesoderm (IM)-derived cells from human pluripotent stem cells (hPSC). However, the substantial variability between existing protocols for generating IM cells compromises th
Externí odkaz:
https://doaj.org/article/8585e6cabff3402bae19c5750ce15157
Autor:
Yapei Yuan, Huan Chen, Sihua Ou, Baomei Cai, Ruifang Zhang, Yue Qin, Mengjie Pan, Shangtao Cao, Duanqing Pei, Fan Fan Hou
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Background The kidneys require vast amounts of mitochondria to provide ample energy to reabsorb nutrients and regulate electrolyte, fluid, and blood pressure homeostasis. The lack of the human model hinders the investigation of mitochondria
Externí odkaz:
https://doaj.org/article/4b441bcb9a3e4ca78ba2630e0482bf3a
Autor:
Kotaro Sasaki, Akiko Oguchi, Keren Cheng, Yasuhiro Murakawa, Ikuhiro Okamoto, Hiroshi Ohta, Yukihiro Yabuta, Chizuru Iwatani, Hideaki Tsuchiya, Takuya Yamamoto, Yasunari Seita, Mitinori Saitou
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109075- (2021)
Summary: In the early fetal stage, the gonads are bipotent and only later become the ovary or testis, depending on the genetic sex. Despite many studies examining how sex determination occurs from biopotential gonads, the spatial and temporal organiz
Externí odkaz:
https://doaj.org/article/e61a3b1420ab4cfe9366c4029984c419
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Akademický článek
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Akademický článek
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Autor:
Navin Gupta, Ryuji Morizane
Publikováno v:
Semin Cell Dev Biol
Kidney organoid technology has led to a renaissance in kidney developmental biology. The complex underpinnings of mammalian kidney development have provided a framework for the generation of kidney cells and tissues from human pluripotent stem cells.
Publikováno v:
AIMS Bioengineering, Vol 3, Iss 3, Pp 305-318 (2016)
The kidney is a complex organ whose excretory and regulatory functions are vital for maintaining homeostasis. Previous techniques used to study the kidney, including various animal models and 2D cell culture systems to investigate the mechanisms of r
Externí odkaz:
https://doaj.org/article/f6721db86dba455d985f355c68dd46d3
Autor:
Guillaume Bourque, Yuhong Zhang, Jiannis Ragoussis, Alain Pacis, Yu Chang Wang, Oraly Sanchez-Ferras, Maria Sotiropoulou, Mathieu Bourgey, Maxime Bouchard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The kidney and upper urinary tract develop through reciprocal interactions between the ureteric bud and the surrounding mesenchyme. Ureteric bud branching forms the arborized collecting duct system of the kidney, while ureteric tips promote nephron f
Autor:
Leslie Dale, Fiona C Wardle
Publikováno v:
eLS
During early embryogenesis, the three germ layers, mesoderm, endoderm and ectoderm, must form in the correct positions for normal development to proceed. In the amphibian embryo, mesoderm is induced from cells of the marginal zone, at the equator of