Výsledky vyhledávání - "Interleukin-4/biosynthesis"

Synthesis of C-5″ and C-6″-modified α-GalCer analogues as iNKT-cell agonists

Autor: Joren Guillaume, Dirk Elewaut, Nora Pauwels, Sandrine Aspeslagh, Dirk M. Zajonc, Serge Van Calenbergh

Publikováno v: BIOORGANIC & MEDICINAL CHEMISTRY

Alpha-galactosyl ceramide (α-GalCer) is a prototypical synthetic ligand of invariant natural killer T (iNKT) cells. Upon presentation by the MHC class I-like molecule CD1d, this glycolipid stimulates iNKT cells to secrete a vast amount of both pro-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6497502e5a3999f5624f254e349f110d
https://doi.org/10.1016/j.bmc.2015.04.068

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Potential non-T cells source of interleukin-4 in food allergy

Autor: Madhan Masilamani, Hugh A. Sampson, Jean-Christoph Roger J-P Caubet, Lloyd Mayer, Neisha A Rivers

Publikováno v: Pediatric Allergy and Immunology, Vol. 25, No 3 (2014) pp. 243-9

Recently, a study from the Consortium of Food Allergy Research (CoFAR) showed that allergen-induced IL-4 expression in CD25(+) mononuclear cells was increased in allergic patients. However, they did not find the expected increase in GATA-3 expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cbf52df130019f5811c063edeff6aa
https://pubmed.ncbi.nlm.nih.gov/24576111

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Metabolic-cytokine responses to a second immunological challenge with LPS in mice withT. gondiiinfection

Autor: Hernan R. Chang, Lucien Girardier, Irène Garcia, Rudolf Lucas, Abdul G. Dulloo, Denis Arsenijevic, Jean-Claude Pechère, Josiane Seydoux

Publikováno v: American Journal of Physiology, Vol. 274, No 3 Pt 1 (1998) pp. E439-445
Europe PubMed Central
Scopus-Elsevier

Injection of 10 cysts of Toxoplasma gondii (Me49 strain) into Swiss Webster mice results in 1) an acute phase of infection lasting for 2–3 wk, characterized by weight loss, and 2) a chronic phase in which surviving mice show either partial weight r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef32e928840ad6703164ad07dc39586e
https://doi.org/10.1152/ajpendo.1998.274.3.e439

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Cytokine production by T-cell clones from bronchoalveolar lavage fluid of patients with asthma and healthy subjects

Publikováno v: European respiratory journal. Supplement. 22:95s-103s

Cytokines produced by T-lymphocytes play an important regulatory role in inflammation in the airways of asthmatic patients. Our aim was to analyse the cytokine production by T-cell clones from bronchoalveolar lavage fluid (BAL) of patients with aller

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::0b3c3aeea21059f91e46e4bbd169882f

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Lymphocytes in Peyer patches regulate clinical tolerance in a murine model of food allergy

Autor: Christophe P. Frossard, Conrad Hauser, Philippe Eigenmann, Laurence Tropia

Publikováno v: Journal of Allergy and Clinical Immunology, Vol. 113, No 5 (2004) pp. 958-64

Background Food allergy can lead to severe, potentially life-threatening anaphylactic reactions. To generate efficient strategies aimed at an active cure, a better understanding of the pathogenic mechanisms is strongly needed. Objective To investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f79298fc8e6017180e0c12bc90a3e2
https://archive-ouverte.unige.ch/unige:55631

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Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha

Autor: Carlo, Chizzolini, Yann, Parel, Carmelina, De Luca, Alan, Tyndall, Anita, Akesson, Agneta, Scheja, Jean-Michel, Dayer

Publikováno v: Arthritis and Rheumatism, Vol. 48, No 9 (2003) pp. 2593-604

In systemic sclerosis (SSc; scleroderma), T cells infiltrate organs undergoing fibrotic changes and may participate in dysregulated production of collagen by fibroblasts. The objective of this study was to functionally characterize T cells infiltrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8793b8980147df6cee7a0290ffee5192
https://archive-ouverte.unige.ch/unige:44716

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Protective effect of Rolipram in experimental autoimmune neuritis: protection is associated with down-regulation of IFN-gamma and inflammatory chemokines as well as up-regulation of IL-4 in peripheral nervous system

Autor: Abbas, N., Zou, L. P., Pelidou, S. H., Winblad, B., Zhu, J.

Rolipram, a phosphodiesterase type 4 inhibitor, is reported to have anti-inflammatory effects. It can markedly downregulate antigen-driven T cell proliferation and suppress TNF-(alpha and TNF-beta production in vitro and in vivo, which have led to it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::4a2426bf247f4a8e10f182a4e97af59e
http://olympias.lib.uoi.gr/jspui/handle/123456789/18958

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T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching

Autor: Sanjiv A. Luther, Kai-Michael Toellner, Richard K.-W. Choy, Daniel Man-Yuen Sze, Hans Acha-Orbea, Dale R. Taylor, Ian C. M. MacLennan

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 187, no. 8, pp. 1193-1204

The respective production of specific immunoglobulin (Ig)G2a or IgG1 within 5 d of primary immunization with Swiss type mouse mammary tumor virus [MMTV(SW)] or haptenated protein provides a model for the development of T helper 1 (Th1) and Th2 respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c94712a5fccd646dbb48192b8abad1b
https://pubmed.ncbi.nlm.nih.gov/9547331

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Cytokine production by T-cell clones from bronchoalveolar lavage fluid of patients with asthma and healthy subjects

Autor: Krouwels, F H, Hol, B E, Bruinier, B, Lutter, R, Jansen, H M, Out, T A

Publikováno v: European respiratory journal. Supplement, 22, 95s-103s. European Respiratory Society

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::938ce9e12516b5769a96e77c1f2a4678
https://pure.amc.nl/en/publications/cytokine-production-by-tcell-clones-from-bronchoalveolar-lavage-fluid-of-patients-with-asthma-and-healthy-subjects(ca25e3fc-da96-422e-a740-b82a3b58b0a1).html

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CTLA4-Ig inhibits optimal T helper 2 cell development but not protective immunity or memory response to Nippostrongylus brasiliensis

Autor: Harris, N. L., Peach, R. J., Ronchese, F.

The B7 co-stimulatory pathway is critical to T cell activation, however its role in the generation of Th2 cells in vivo remains controversial. We have studied the role of B7 co-stimulation in the development of a Th2 immune response to the nematode p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______185::cb61667b0df06fa693fd9c28c0d5b0e4
https://infoscience.epfl.ch/record/143000

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