Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Interleukin-36"'
Autor:
Johannes Pawlowski, Tatsiana Pukhalskaya, Kelly Cordoro, Marina Kristy Ibraheim, Jeffrey P. North
Publikováno v:
Dermatopathology, Vol 11, Iss 3, Pp 230-237 (2024)
Netherton syndrome (NS) is a rare autosomal recessive disorder that occurs due to a loss-of-function mutation in SPINK5; this loss results in significant inflammation, as well as perturbations of the skin barrier’s integrity and functionality. Whil
Externí odkaz:
https://doaj.org/article/d032c09be15944bba834221b39c10ba1
Autor:
Liz S. Gea, Julia C. K. El Dib, Omar Algazal, Eduardo C.N. Constantino, Vera L. A. Nasser, João R. Antonio
Publikováno v:
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, Vol 82, Iss 4 (2024)
Generalized pustular psoriasis (GPP) is characterized by an acute and severe variant of psoriasis, often accompanied by systemic symptoms, with the eruption of multiple sterile pustules over an area of erythema, associated or not with the form of pla
Externí odkaz:
https://doaj.org/article/8b4ebf12212544cab6d9ad60d04dc25b
Publikováno v:
Indian Journal of Dermatology, Vol 69, Iss 3, Pp 232-237 (2024)
Background: Rosacea is a chronic inflammatory skin disease. Previous studies have determined that IL-36, IL-37, and IL-38 may play a role in the pathogenesis of various inflammatory diseases. Aims and Objectives: The present study aims to evaluate th
Externí odkaz:
https://doaj.org/article/25aa93ac6baa49548785007e0d16e33b
Autor:
Violetta A. Kovtunova, Sergey A. Altukhov, Ludmila P. Voronina, Elvira G. Bakhmutova, Olga V. Zhizhimova
Publikováno v:
Клинический разбор в общей медицине, Vol 5, Iss 6, Pp 89-94 (2024)
Generalized pustular psoriasis (GPP), being a chronic inflammatory systemic disease, significantly reduces the quality of life of patients, leads to disability and increases the risk of mortality. Representing one of the most severe variants of the d
Externí odkaz:
https://doaj.org/article/50bb8faeb26849b79c6142ba02ee8b78
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 539-545 (2024)
Joseph F Merola,1,* Ahmad Z Amin2,* 1Brigham and Women’s Hospital, Boston, Massachusetts, USA; 2Northwestern University Feinberg, School of Medicine, Chicago, Illinois, USA*These authors contributed equally to this workCorrespondence: D
Externí odkaz:
https://doaj.org/article/cfdb7467dbd2499f8476e6e7e1d581d6
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 16, Pp 3629-3643 (2023)
Lu Wei,1 Buxin Zhang,2 Li Wang,2 Juntao Xu,2 Aimin Liu1,2 1Department of Dermatology, Henan University of Chinese Medicine, Zhengzhou, Henan, People’s Republic of China; 2Department of Dermatology, Henan Province Hospital of Traditional Chinese Med
Externí odkaz:
https://doaj.org/article/228eeba76b91421b9cf27885e2707172
Publikováno v:
Linchuang shenzangbing zazhi, Vol 23, Iss 11, Pp 951-956 (2023)
As an important member of IL-1 family, interleukin 36 (IL-36) is a key regulator of inflammation. Its proinflammatory agonists are composed of IL-36α, IL-36β and IL-36γ while its antagonists include IL-36Ra and IL-38. And co-receptor of IL-36 subf
Externí odkaz:
https://doaj.org/article/86dae2b5ec2d4eeb926f40afeb312689
Autor:
Pan Kang, Jianru Chen, Shiyu Wang, Shaolong Zhang, Shuli Li, Sen Guo, Pu Song, Ling Liu, Gang Wang, Tianwen Gao, Weigang Zhang, Chunying Li
Publikováno v:
Journal of Innate Immunity, Vol 15, Iss 1, Pp 876-892 (2023)
Psoriasis is a common inflammatory skin disease, in which epidermal keratinocytes play a vital role in its pathogenesis by acting both as the responder and as the accelerator to the cutaneous psoriatic immune response. Advanced glycation end products
Externí odkaz:
https://doaj.org/article/dbd268ef2f1e4dbfa71537cd8ef99f1e
Autor:
Tsen-Fang Tsai, Min Zheng, Yangfeng Ding, Zhiqi Song, Quanzhong Liu, Ying Chen, Hanzhao Hu, Jinhua Xu
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 12, Pp 3097-3110 (2023)
Abstract Introduction Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening skin disease. The global Effisayil 1 study investigated the efficacy and safety of spesolimab, a humanized monoclonal antibody targeting the IL-36 r
Externí odkaz:
https://doaj.org/article/c1c887e2b8cd4b5c9b636241d0b82f68
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 16, Pp 2911-2917 (2023)
Eingun James Song,1,* Clive Liu2,* 1Frontier Dermatology, Mill Creek, Washington, USA; 2Bellevue Dermatology Clinic, Bellevue, Washington, USA*These authors contributed equally to this workCorrespondence: Dr Eingun James Song, Email Eingun.Song@front
Externí odkaz:
https://doaj.org/article/dd5274bb300a40b79d51d1870c3c2291