Nationwide differences in cytology fixation and processing methods and their impact on interlaboratory variation in PD-L1 positivity

Autor: Bregje M. Koomen, Mirthe de Boer, Carmen van Dooijeweert, Anne S. R. van Lindert, Ivette A. G. Deckers, Quirinus J. M. Voorham, Stefan M. Willems

Publikováno v: Virchows Archiv, 707–720. SPRINGER

Programmed death ligand-1 (PD-L1) immunostaining, which aids clinicians in decision-making on immunotherapy for non-small cell lung cancer (NSCLC) patients, is sometimes performed on cytological specimens. In this study, differences in cytology fixat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2015ab99de6706def86ddfa8e43ea8
https://doi.org/10.1007/s00428-022-03446-w

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Significant Inter- and Intralaboratory Variation in Gleason Grading of Prostate Cancer: A Nationwide Study of 35,258 Patients in The Netherlands

Autor: Ivette A. G. Deckers, Britt B. M. Suelmann, Trudy G. N. Jonges, Rachel N. Flach, Peter-Paul M. Willemse, Carmen van Dooijeweert, Paul J. van Diest, Richard P. Meijer

Publikováno v: Cancers
Volume 13
Issue 21
Cancers, Vol 13, Iss 5378, p 5378 (2021)

Simple Summary Gleason grading of prostate cancer is essential for treatment strategies and patient prognosis. Previous studies showed grading variation between pathologists when grading prostate cancer. Our study analyzed the presence and extent of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf90aae2b8888506d04e04137ed661c
http://europepmc.org/articles/PMC8582481

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Therapeutic Drug Monitoring of Lithium: A Study of the Accuracy and Analytical Variation Between Laboratories in Denmark

Autor: Per Damkier, Tina Mose, Steen Antonsen, Magnus Petersen

Publikováno v: Mose, T, Damkier, P, Petersen, M & Antonsen, S 2015, ' Therapeutic Drug Monitoring of Lithium : A Study of the Accuracy and Analytical Variation Between Laboratories in Denmark ', Therapeutic Drug Monitoring, vol. 37, no. 4, pp. 466-471 . https://doi.org/10.1097/FTD.0000000000000198

BACKGROUND: Serum lithium is monitored to ensure levels within the narrow therapeutic window. This study examines the interlaboratory variation and inaccuracy of lithium monitoring in Denmark.METHODS: In 16 samples consisting of (1) control materials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a03fbc9fa58cfa1c9ba274a7288e64d
https://pubmed.ncbi.nlm.nih.gov/26192891