Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Interferon-gamma/pharmacology"'
Autor:
Elvira, Bernat, Vandenbempt, Valerie, Bauzá-Martinez, Julia, Crutzen, Raphaël, Negueruela, Javier, Ibrahim, Hazem, Winder, Matthew L., Brahma, Manoja K., Vekeriotaite, Beata, Martens, Pieter Jan, Singh, Sumeet Pal, Rossello, Fernando, Lybaert, Pascale, Otonkoski, Timo, Gysemans, Conny, Wu, Wei, Gurzov, Esteban N., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Diabetes, 71(4), 653. American Diabetes Association Inc.
Type 1 diabetes (T1D) results from autoimmune destruction of β-cells in the pancreas. Protein tyrosine phosphatases (PTPs) are candidate genes for T1D and play a key role in autoimmune disease development and β-cell dysfunction. Here, we assessed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6442d0189b7349e84a6fc8180e102fc7
https://dspace.library.uu.nl/handle/1874/424473
https://dspace.library.uu.nl/handle/1874/424473
Autor:
Michal Bassani-Sternberg, Julien Racle, Chloe Chong, Fabio Marino, Markus Müller, Roy Thomas Daniel, HuiSong Pak, George Coukos, David Gfeller
Publikováno v:
Molecular & cellular proteomics, vol. 17, no. 3, pp. 533-548
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Comprehensive knowledge of the human leukocyte antigen (HLA) class-I and class-II peptides presented to T-cells is crucial for designing innovative therapeutics against cancer and other diseases. However methodologies for their purification for mass-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9613fdffc6e491be74f262feb3fc42
https://serval.unil.ch/resource/serval:BIB_A056F0253744.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_A056F0253744.P001/REF.pdf
Autor:
Anastase Spiliopoulos, Marie-Marthe Philippeaux, John Robert, Jean-Pierre Bargetzi, Jean-Claude Pache, Jacques Mauël
Publikováno v:
European Journal of Cell Biology, Vol. 88, No 4 (2009) pp. 243-256
Freshly isolated, starch-elicited mouse peritoneal macrophages (Mø) attached very efficiently to type I collagen in vitro, if collagen molecules were arranged in ordered supra-molecular assemblies corresponding to the precursor native fibrils. After
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae218dff119058d1765c8ac5a4e3ca5f
https://doi.org/10.1016/j.ejcb.2008.11.002
https://doi.org/10.1016/j.ejcb.2008.11.002
Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site
Autor:
Elisa Leimgruber, Natalia Rybtsova, Queralt Seguín-Estévez, Walter Reith, Philipp Bucher, Giovanna Ambrosini, Isabelle Dunand-Sauthier, Christoph D. Schmid
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Vol. 37, No 8 (2009) pp. 2514-2528
Nucleic Acids Research, Vol. 37, No 8 (2009) pp. 2514-2528
Nucleosome depletion at transcription start sites (TSS) has been documented genome-wide in multiple eukaryotic organisms. However, the mechanisms that mediate this nucleosome depletion and its functional impact on transcription remain largely unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4099270a6678b4081bd84b2451f3e08
http://europepmc.org/articles/PMC2677874
http://europepmc.org/articles/PMC2677874
Autor:
Walter Reith, Elisa Leimgruber, Natalia Rybtsova, Queralt Seguín-Estévez, Michal Krawczyk, Isabelle Dunand-Sauthier
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Vol. 35, No 10 (2007) pp. 3431-3441
Nucleic Acids Research, Vol. 35, No 10 (2007) pp. 3431-3441
Posttranslational histone modifications associated with actively expressed genes are generally believed to be introduced primarily by histone-modifying enzymes that are recruited by transcription factors or their associated co-activators. We have per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bc845ba5f3661b106ed2eaa92bc357
http://europepmc.org/articles/PMC1904273
http://europepmc.org/articles/PMC1904273
Autor:
Björn Dahlöf, Florianne Monnet-Tschudi, Veronica Valero-Esquitino, Daniel C. Villela, Anders Hallberg, Ludovit Paulis, U. Muscha Steckelings, Thomas Unger, Pawel Namsolleck, Meng Liu, Franziska Lucht, Tobias Stubbe, Christa Thoene-Reineke, Christine Brandt, Kristin Lucht, Colin Sumners, Friederike Ebner, Leon Alexander Danyel
Publikováno v:
Valero-Esquitino, V, Lucht, K, Namsolleck, P, Monnet-Tschudi, F, Stubbe, T, Lucht, F, Liu, M, Ebner, F, Brandt, C, Danyel, L A, Villela, D C, Paulis, L, Thoene-Reineke, C, Dahlöf, B, Hallberg, A, Unger, T, Sumners, C & Steckelings, U M 2015, ' Direct angiotensin type 2 receptor (AT 2 R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice ', Clinical Science, vol. 128, no. 2, pp. 95–109 . https://doi.org/10.1042/CS20130601
Clinical Science, 128(2), 95-109. Portland Press Ltd.
Clinical Science, 128(2), 95-109. Portland Press Ltd.
In the present study, we evaluated stimulation of the angiotensin type 2 receptor (AT2R) by the selective non-peptide agonist Compound 21 (C21) as a novel therapeutic concept for the treatment of multiple sclerosis using the model of experimental aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73139743d95ac94a4a519c5ee7428279
https://portal.findresearcher.sdu.dk/da/publications/906bc3b1-5591-45bc-a2eb-c76eada71aab
https://portal.findresearcher.sdu.dk/da/publications/906bc3b1-5591-45bc-a2eb-c76eada71aab
Publikováno v:
Scopus-Elsevier
Fas-mediated apoptosis has been proposed to play an important role in homeostasis. Fas triggers apoptosis after stimulation by its ligand FasL or the Fas ligand agonist anti-Fas antibody through a mitochondria-dependent or -independent pathway, and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4b634672592556e06737515c41834e
http://hdl.handle.net/2115/53731
http://hdl.handle.net/2115/53731
Autor:
Stephanie Zwicker, D. Bureik, Aleksandra Batycka-Baran, Thomas Ruzicka, Simon Rothenfusser, Andreas Schmidt, Ronald Wolf, Michel Gilliet, Eva Hattinger, Peter-Arne Gerber
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175153 (2017)
PloS one, vol. 12, no. 4, pp. e0175153
PLoS ONE
PloS one, vol. 12, no. 4, pp. e0175153
PLoS ONE
IL-1β is a potent player in cutaneous inflammation and central for the development of a Th17 micro-milieu in autoinflammatory diseases including psoriasis. Its production is controlled at the transcriptional level and by subsequent posttranslational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0206ce2320093f408cfb6eb3ea3f67da
https://doi.org/10.1371/journal.pone.0175153
https://doi.org/10.1371/journal.pone.0175153
Autor:
Luca Bernasconi, Tobias Suter, Jean-Marc Waldburger, Adriano Fontana, Krzysztof Masternak, Walter Reith, Annick Mühlethaler-Mottet, Salomé Landmann, Jean-François Arrighi, Conrad Hauser
Publikováno v:
Journal of Experimental Medicine, Vol. 194, No 4 (2001) pp. 379-391
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Cell surface expression of major histocompatibility complex class II (MHCII) molecules is increased during the maturation of dendritic cells (DCs). This enhances their ability to present antigen and activate naive CD4+ T cells. In contrast to increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703b562837866cb9b1b778b4c94f61de
https://doi.org/10.1084/jem.194.4.379
https://doi.org/10.1084/jem.194.4.379
Autor:
Sharon Pitts-Meek, Francesco Di Marco, Michel Aguet, Bernard Sordat, Susan D. Spencer, Jeff Hooley, Anne M. Ryan, Michele Bauer, Verna C. Gibbs
Publikováno v:
Journal of Experimental Medicine, vol. 187, no. 4, pp. 571-578
The Journal of Experimental Medicine
The Journal of Experimental Medicine
The orphan receptor CRF2-4 is a member of the class II cytokine receptor family (CRF2), which includes the interferon receptors, the interleukin (IL) 10 receptor, and tissue factor. CRFB4, the gene encoding CRF2-4, is located within a gene cluster on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c27592f2bc9f3ced544a4fbcc1a764
https://doi.org/10.1084/jem.187.4.571
https://doi.org/10.1084/jem.187.4.571