Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Interferon-gamma/metabolism"'
Autor:
Garnier, L., Pick, R., Montorfani, J., Sun, M., Brighouse, D., Liaudet, N., Kammertoens, T., Blankenstein, T., Page, N., Bernier-Latamani, J., Tran, N.L., Petrova, T.V., Merkler, D., Scheiermann, C., Hugues, S.
Publikováno v:
Science advances, vol. 8, no. 23, pp. eabl5162
Tumor-associated lymphatic vessels promote metastasis and regulate antitumor immune responses. Here, we assessed the impact of cytotoxic T cells on the local lymphatic vasculature and concomitant tumor dissemination during an antitumor response. Inte
Autor:
Ververs, Francesca A, Engelen, Suzanne E, Nuboer, Roos, Vastert, Bas, van der Ent, Cornelis K, Van't Land, Belinda, Garssen, Johan, Monaco, Claudia, Boes, Marianne, Schipper, Henk S, Afd Pharmacology, Pharmacology
Publikováno v:
Scientific Reports, 11(1), 1. NLM (Medline)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Invariant Natural Killer T (iNKT) cells respond to the ligation of lipid antigen-CD1d complexes via their T-cell receptor and are implicated in various immunometabolic diseases. We considered that immunometabolic factors might affect iNKT cell functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7debcd79c6fc17fa2ffdb758284f146
https://dspace.library.uu.nl/handle/1874/418390
https://dspace.library.uu.nl/handle/1874/418390
Autor:
Malcolm J. McConville, Fernando Souza-Fonseca-Guimaraes, Motti Gerlic, Komal Kanojia, Adele Preaudet, Benjamin T. Kile, Marcel R. de Zoete, Man Lyang Kim, Konstantinos A. Kouremenos, Yasunori Ogura, Richard A. Flavell, David P De Souza, Cassandra R. Harapas, Tracy L Putoczki, Stephen Wilcox, Hazel Tye, Seth L. Masters, Graham L. Radford-Smith, Sinéad C. Corr, Martha Zakrzewski, Jocelyn Sietsma Penington, Leesa F. Wockner, Chien-Hsiung Yu, Anthony T. Papenfuss, Lisa A. Simms, Lisa A. Mielke
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9(1). Nature Publishing Group
Nature Communications, 9(1). Nature Publishing Group
Anti-microbial signaling pathways are normally triggered by innate immune receptors when detecting pathogenic microbes to provide protective immunity. Here we show that the inflammasome sensor Nlrp1 aggravates DSS-induced experimental mouse colitis b
Autor:
E. J. Remarque, Vinod Sommandas, Sumera Younis, Christophe Barnier-Quer, Patrice M. Dubois, Martin Friede, Clemens H. M. Kocken, Nicole vd.Werff, Nicolas Collin, Simon Heuking, Livia Brunner
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Immunology
BMC immunology, vol. 19, no. 1, pp. 6
BMC Immunology
BMC immunology, vol. 19, no. 1, pp. 6
Background: The need for rapid and accurate comparison of panels of adjuvanted vaccine formulations and subsequent rational down selection, presents several challenges for modern vaccine development. Here we describe a method which may enable vaccine
Autor:
Gianluca Carlesso, Christopher Morehouse, Matthew A. Sleeman, Claire Willis, Michio Tomura, Ana Camelo, Fernanda Pilataxi, Emma E Dutton, Dominika W Gajdasik, Emma L. Bishop, Remi Fiancette, David R. Withers, Margherita Coccia, Arnaud M. Didierlaurent
Publikováno v:
Science Immunology, Vol. 4, No 35 (2019) P. eaau8082
Tissue residency is considered a defining feature of the innate lymphoid cell (ILC) populations located within mucosal and adipose tissues. ILCs are also present within all lymphoid tissues, but whether ILCs migrate between lymphoid and nonlymphoid s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ed7968fe59432592f228615c8e12fc
https://europepmc.org/articles/PMC7018521/
https://europepmc.org/articles/PMC7018521/
Autor:
Maximilian Rentschler, Yan Chen, Jana Pahl, Laura Soria-Martinez, Heidi Braumüller, Ellen Brenner, Oliver Bischof, Martin Röcken, Thomas Wieder
Publikováno v:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry, 2018, 51 (3), pp.1103-1118. ⟨10.1159/000495490⟩
Cellular Physiology and Biochemistry, Karger, 2018, 51 (3), pp.1103-1118. ⟨10.1159/000495490⟩
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1103-1118 (2018)
Cellular Physiology and Biochemistry, 2018, 51 (3), pp.1103-1118. ⟨10.1159/000495490⟩
Cellular Physiology and Biochemistry, Karger, 2018, 51 (3), pp.1103-1118. ⟨10.1159/000495490⟩
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1103-1118 (2018)
International audience; BACKGROUND/AIMS:Cellular senescence, or permanent growth arrest, is known as an effective tumor suppressor mechanism that can be induced by different stressors, such as oncogenes, chemotherapeutics or cytokine cocktails. Previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f2d1fd6907d81dc0bcd1b87abd9d8d03
https://hal.science/hal-02349029/document
https://hal.science/hal-02349029/document
Autor:
M Bazewicz, Dafina Draganova, Catherine Bruyns, Liliane Tenenbaum, Abdel Chtarto, Francois Willermain, V Elmaleh, Maya Makhoul, Laure Caspers
Publikováno v:
Neuroscience letters, vol. 630, pp. 209-215
The purpose of this study was to investigate the in vitro effect of Suppressor Of Cytokine Signaling 1 (SOCS1) overexpression in retinal pigment epithelium (RPE) cells on their activation by pro-inflammatory cytokines IFNγ, TNFα and IL-17. Retinal
Autor:
E. M. D. L. van der Heijden, Akinbowale Olajide Jenkins, Anita Luise Michel, Dave Cooper, Victor P.M.G. Rutten
Publikováno v:
Veterinary Immunology and Immunopathology, 169, 68. Elsevier
van der Heijden, E M D L, Jenkins, A O, Cooper, D V, Rutten, V P M G & Michel, A L 2015, ' Field application of immunoassays for the detection of Mycobacterium bovis infection in the African buffalo (Syncerus caffer) ', Veterinary Immunology and Immunopathology, vol. 169, pp. 68-73 . https://doi.org/10.1016/j.vetimm.2015.12.003
van der Heijden, E M D L, Jenkins, A O, Cooper, D V, Rutten, V P M G & Michel, A L 2015, ' Field application of immunoassays for the detection of Mycobacterium bovis infection in the African buffalo (Syncerus caffer) ', Veterinary Immunology and Immunopathology, vol. 169, pp. 68-73 . https://doi.org/10.1016/j.vetimm.2015.12.003
The African buffalo (Syncerus caffer) is considered the most important maintenance host of bovine tuberculosis (BTB) in wildlife in Southern Africa. The diagnosis of Mycobacterium bovis infection in this species mostly relies on the single intraderma
Autor:
Nicolet, Benoît P, Guislain, Aurélie, van Alphen, Floris P J, Gomez-Eerland, Raquel, Schumacher, Ton N M, van den Biggelaar, Maartje, Wolkers, Monika C, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6686. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6686-6696. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6686-6696. National Academy of Sciences
Cytotoxic CD8 + T cells can effectively kill target cells by producing cytokines, chemokines, and granzymes. Expression of these effector molecules is however highly divergent, and tools that identify and preselect CD8 + T cells with a cytotoxic expr
Autor:
Mads A. Røpke, Mads Thomassen, Mark Burton, Ole Clemmensen, Bjarne Winther Kristensen, Torben A Kruse, Flemming Andersen, Peter S. Friedmann, Qihua Tan, Lone Skov, Klaus Ejner Andersen, Kristian Fredløv Mose, Thomas Litman
Publikováno v:
Mose, K F, Burton, M, Thomassen, M, Andersen, F, Kruse, T A, Tan, Q, Skov, L, Almose Røpke, M, Litman, T, Clemmensen, O, Kristensen, B W, S. Friedmann, P & Andersen, K E 2017, ' The gene expression and immunohistochemical time-course of diphenylcyclopropenone induced contact allergy in healthy humans following repeated epicutaneous challenges ', Experimental Dermatology, vol. 26, no. 10, pp. 926–933 . https://doi.org/10.1111/exd.13345
The gene expression time-course of repeated challenge of contact allergy (CA) remains largely unknown. Therefore, using diphenylcyclopropenone (DPCP) as model allergen in healthy humans we set out to examine: (i) the monotonous and complex gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47d24743fb8232aaa16712a6c1d57d9
https://portal.findresearcher.sdu.dk/da/publications/58d29cb9-c3eb-4e3f-b654-8296a5c44d85
https://portal.findresearcher.sdu.dk/da/publications/58d29cb9-c3eb-4e3f-b654-8296a5c44d85