Zobrazeno 1 - 10
of 2 152
pro vyhledávání: '"Interferon-β"'
Publikováno v:
Consilium Medicum, Vol 26, Iss 11, Pp 752-758 (2024)
Current approaches to treating multiple sclerosis aim at controlling disease activity. Despite the variety of agents that have proven their effectiveness and were introduced in practice in the last decade, the use of the interferon β group remains r
Externí odkaz:
https://doaj.org/article/ba3ee63b13934f50a5ec31d57c690f99
Autor:
Noah M. Chernosky, Ilaria Tamagno, Kelsey L. Polak, E. Ricky Chan, Xueer Yuan, Mark W. Jackson
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-24 (2024)
Abstract Background Patients with Triple Negative Breast Cancer (TNBC) currently lack targeted therapies, and consequently face higher mortality rates when compared to patients with other breast cancer subtypes. The tumor microenvironment (TME) cytok
Externí odkaz:
https://doaj.org/article/cbbf1e0273234c978461d7f8a628e485
Publikováno v:
Central Asian Journal of Medical Hypotheses and Ethics, Vol 5, Iss 3, Pp 193-203 (2024)
In this study, type I interferon (IFN-α ve IFN-β) levels, viral load levels, the relationship between viral load and interferons, and the relationship between interferon levels and disease severity and mortality in patients with Crimean-Congo Haemo
Externí odkaz:
https://doaj.org/article/b4b10d4cadb74f45a2580730959101f2
Autor:
Mayuki Tachizaki, Sho Sakamoto, Yuri Kobori, Yoshiya Asano, Shogo Kawaguchi, Kazuhiko Seya, Hiroshi Tanaka, Eiji Morita, Tadaatsu Imaizumi
Publikováno v:
FEBS Open Bio, Vol 14, Iss 8, Pp 1303-1319 (2024)
Viral infections in tubular epithelial cells lead to the production of inflammatory cytokines by innate immunity, causing tubulointerstitial nephritis. TLR3 recognizes viral infections and acts via the activation of interferon (IFN)/IFN‐stimulated
Externí odkaz:
https://doaj.org/article/494995e0ba894709b891986b08201d5a
Autor:
Biao Dou, Xiao Wu, Yurong He, Guihua Xu, Huan Zhang, Qilin Huang, Xuan Chen, Naifan Duan, Linqiong Zhou, Wei Zhang, Huazhang An, Yuejuan Zheng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundFei-Yan-Qing-Hua decoction (FYQHD) is derived from the well-known Ma Xing Shi Gan decoction, which was documented in Zhang Zhong Jing’s “Treatise on Exogenous Febrile Disease” during the Han Dynasty. Although FYQHD has been used in th
Externí odkaz:
https://doaj.org/article/384234b297564c8d84050b14be896df2
Autor:
Zhixuan Xiong, Jingjing Cao, Mengchen Xiu, Aiying Li, Xiangzhi Li, Youming Zhang, Qinghua Zeng, Ying Hu, Yuling Yang, Huansheng Wu
Publikováno v:
Poultry Science, Vol 103, Iss 9, Pp 103989- (2024)
ABSTRACT: Protein arginine methyltransferases (PRMTs) in mammals play a role in various signaling pathways, such as virus infection, inflammasome responses, and cancer growth. While some PRMTs have been found to regulate interferon production in mamm
Externí odkaz:
https://doaj.org/article/3502d0c84a8f4fc9a28a273c4f377853
Autor:
Martin Leu, Hanibal Bohnenberger, Manuel Guhlich, Markus Anton Schirmer, Yiannis Pilavakis, Hendrik Andreas Wolff, Stefan Rieken, Leif Hendrik Dröge
Publikováno v:
Cancer Reports, Vol 7, Iss 8, Pp n/a-n/a (2024)
Abstract Background and Aim The German NPC‐GPOH trials introduced treatment including neoadjuvant chemotherapy, radiochemotherapy (RCT) and antiviral treatment in patients aged 25 years or younger with nasopharyngeal cancer (NPC). We conducted a re
Externí odkaz:
https://doaj.org/article/212756e107064bf7a509eb55d7510d11
Publikováno v:
Viruses, Vol 16, Iss 8, p 1240 (2024)
Arteriviruses can establish persistent infections in animals such as equids, pigs, nonhuman primates, rodents, and possums. Some Arteriviruses can even cause overt and severe diseases such as Equine Arteritis in horses and Porcine Reproductive and Re
Externí odkaz:
https://doaj.org/article/43da1961d5774f74ab3afbcec13d8b33
Autor:
Fakhr Fakhr, Shaygannejad Shaygannejad, Khorrami Khorrami, Saberi Saberi, Mirmosayyeb Mirmosayyeb, Sadeghi Sadeghi, Kheirollahi Kheirollahi
Publikováno v:
Global Medical Genetics, Vol 10, Iss 03, Pp 164-171 (2023)
Interferon (IFN)-β is the first-line disease management choice in multiple sclerosis (MS) with profound effects; however, in up to 50% of patients, clinical response does not occur. Ascertaining the responding state, need a long-term clinical follow
Externí odkaz:
https://doaj.org/article/c49adbbb018243f3b660bca1eea5f153
Autor:
Ying-Xing Yue, Bing-Bing Jia, Ji-Rong Wang, Ying-Zheng Weng, Gen-Xiang Mao, Yan Lu, Jing Yan, Zhou-Xin Yang
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23001- (2023)
Viruses have become a major threat to human health. Interferon-β (IFN-β) has a key role in the antivirus process, as it can increase the expression of antivirus-associated genes. Itaconate and its derivatives can regulate the immune response, secre
Externí odkaz:
https://doaj.org/article/a84ac01b27b947ddafef62946ae66f70