Zobrazeno 1 - 10
of 369
pro vyhledávání: '"Interferon signature"'
Autor:
Ellen D. Kaan, Tammo E. Brunekreef, Julia Drylewicz, Lucas L. van den Hoogen, Maarten van der Linden, Helen L. Leavis, Jacob M. van Laar, Michiel van der Vlist, Henny G. Otten, Maarten Limper
Publikováno v:
Journal of Translational Autoimmunity, Vol 9, Iss , Pp 100246- (2024)
Objective: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a variety of disease symptoms and an unpredictable clinical course. To improve treatment outcome, stratification based on immunological manifestations commonly se
Externí odkaz:
https://doaj.org/article/04b3c7987a8e4c35b53ca455a1fda635
Autor:
Anastasia S. Avdeeva, Andrey P. Aleksankin, Elena V. Tchetina, Yu. N. Gorbunova, Tatiana V. Popkova, Galina A. Markova, Tatiana A. Panafidina, Evgeny L. Nasonov
Publikováno v:
Научно-практическая ревматология, Vol 62, Iss 4 (2024)
The aim – to evaluate subpopulations of B lymphocytes and features of interferon (IFN) status in patients with systemic lupus erythematosus (SLE), to clarify the relationship of immunological parameters with clinical manifestations of the diseaseMa
Externí odkaz:
https://doaj.org/article/eb2ddf7e6c8a42b8913fe921a4175133
Autor:
Irene Cecchi, Massimo Radin, Alice Barinotti, Silvia Grazietta Foddai, Elisa Menegatti, Dario Roccatello, Ana Suárez, Savino Sciascia, Javier Rodríguez-Carrio
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWhile the type I interferon (IFN-I) pathway is crucial in autoimmunity, its role in antiphospholipid antibody (aPL)-positive subjects, including aPL carriers and antiphospholipid syndrome (APS) patients, is poorly understood. This study a
Externí odkaz:
https://doaj.org/article/47b645d1dc7e45b7be4c7514b5b47006
Akademický článek
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Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background The upregulation of interferon (IFN)-stimulated genes induced by type I IFNs (namely type I IFN signature) in rheumatoid arthritis (RA) patients had implications in early diagnosis and prediction of therapy responses. However, fac
Externí odkaz:
https://doaj.org/article/734a0ec6fe9c4ce3a8e3e193d3ab8e06
Autor:
Takeshi Iwasaki, Ryu Watanabe, Hiromu Ito, Takayuki Fujii, Kenji Okuma, Takuma Oku, Yoshitaka Hirayama, Koichiro Ohmura, Koichi Murata, Kosaku Murakami, Hiroyuki Yoshitomi, Masao Tanaka, Shuichi Matsuda, Fumihiko Matsuda, Akio Morinobu, Motomu Hashimoto
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The factors influencing long-term responses to a tumor necrosis factor inhibitor (TNFi) in rheumatoid arthritis (RA) patients currently remain unknown. Therefore, we herein conducted a multi-omics analysis of TNFi responses in a Japanese RA cohort. B
Externí odkaz:
https://doaj.org/article/9145474307c14f30a6acaadba2dbc46b
Publikováno v:
Современная ревматология, Vol 15, Iss 5, Pp 12-17 (2021)
Objective: to evaluate the expression of interferon-stimulated genes (ISG) – interferon (IFN) signature – in patients with rheumatoid arthritis (RA) and its dynamics during anti-B-cell therapy.Patients and methods.We examined 20 patients with RA
Externí odkaz:
https://doaj.org/article/c1932dbbb9394b34b393a71c1082685e
Autor:
Takayuki Miyamoto, Yoshitaka Honda, Kazushi Izawa, Nobuo Kanazawa, Saori Kadowaki, Hidenori Ohnishi, Masakazu Fujimoto, Naotomo Kambe, Naoya Kase, Takeshi Shiba, Yasuo Nakagishi, Shuji Akizuki, Kosaku Murakami, Masahiro Bamba, Yutaka Nishida, Ayano Inui, Tomoo Fujisawa, Daisuke Nishida, Naomi Iwata, Yoshikazu Otsubo, Shingo Ishimori, Momoko Nishikori, Kiminobu Tanizawa, Tomoyuki Nakamura, Takeshi Ueda, Yoko Ohwada, Yu Tsuyusaki, Masaki Shimizu, Takasuke Ebato, Kousho Iwao, Akiharu Kubo, Toshinao Kawai, Tadashi Matsubayashi, Tatsuhiko Miyazaki, Tomohiro Kanayama, Masahiko Nishitani-Isa, Hiroshi Nihira, Junya Abe, Takayuki Tanaka, Eitaro Hiejima, Satoshi Okada, Osamu Ohara, Megumu K. Saito, Junko Takita, Ryuta Nishikomori, Takahiro Yasumi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeUpregulation of type I interferon (IFN) signaling has been increasingly detected in inflammatory diseases. Recently, upregulation of the IFN signature has been suggested as a potential biomarker of IFN-driven inflammatory diseases. Yet, it rem
Externí odkaz:
https://doaj.org/article/5700023cf0774dc68dac5c83825a3a61
Autor:
Martina Girardelli, Erica Valencic, Valentina Moressa, Roberta Margagliotta, Alessandra Tesser, Serena Pastore, Ottavia Spadola, Emmanouil Athanasakis, Giovanni Maria Severini, Andrea Taddio, Alberto Tommasini
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background Recurrent aphthous stomatitis with systemic signs of inflammation can be encountered in inflammatory bowel disease, Behçet’s disease (BD), Systemic Lupus Erythematosus (SLE). In addition, it has been proposed that cases with ve
Externí odkaz:
https://doaj.org/article/309ae9636f954ccebfde8523183bd813
Autor:
A. S. Avdeeva, E. V. Tchetina, M. V. Cherkasova, G. A. Markova, A. S. Artyuhov, E. B. Dashinimaev, E. L. Nasonov
Publikováno v:
Научно-практическая ревматология, Vol 58, Iss 6, Pp 673-677 (2021)
Objective. To assess the expression of interferon-stimulated genes in patients with rheumatoid arthritis (RA).Material and methods. Twenty patients with RA were examined. All patients received methotrexate therapy at a stable dose (Me 15 [10-17.5] mg
Externí odkaz:
https://doaj.org/article/5b5dd1c9406846bab1d09c5abe31e3d5