Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Autor: Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Rosain, Jérémie, Philippot, Quentin, Manry, Jérémy, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Eto, Shohei, Garcia-Prat, Marina, Bizien, Lucy, Parra-Martínez, Alba, Yang, Rui, Haljasmägi, Liis, Migaud, Mélanie, Särekannu, Karita, Maslovskaja, Julia, de Prost, Nicolas, Tandjaoui-Lambiotte, Yacine, Luyt, Charles-Edouard, Amador-Borrero, Blanca, Gaudet, Alexandre, Poissy, Julien, Morel, Pascal, Richard, Pascale, Cognasse, Fabrice, Troya, Jesus, Trouillet-Assant, Sophie, Belot, Alexandre, Saker, Kahina, Garçon, Pierre, Rivière, Jacques G., Lagier, Jean-Christophe, Gentile, Stéphanie, Rosen, Lindsey B., Shaw, Elana, Morio, Tomohiro, Tanaka, Junko, Dalmau, David, Tharaux, Pierre-Louis, Sene, Damien, Stepanian, Alain, Megarbane, Bruno, Triantafyllia, Vasiliki, Fekkar, Arnaud, Heath, James R., Franco, José Luis, Anaya, Juan-Manuel, Solé-Violán, Jordi, Imberti, Luisa, Biondi, Andrea, Bonfanti, Paolo, Castagnoli, Riccardo, Delmonte, Ottavia M., Zhang, Yu, Snow, Andrew L., Holland, Steven M., Biggs, Catherine M., Moncada-Vélez, Marcela, Arias, Andrés Augusto, Lorenzo, Lazaro, Boucherit, Soraya, Coulibaly, Boubacar, Anglicheau, Dany, Planas, Anna M., Haerynck, Filomeen, Duvlis, Sotirija, Nussbaum, Robert L., Ozcelik, Tayfun, Keles, Sevgi, Bousfiha, Ahmed A., El Bakkouri, Jalila, Ramirez-Santana, Carolina, Paul, Stéphane, Pan-Hammarström, Qiang, Hammarström, Lennart, Dupont, Annabelle, Kurolap, Alina, Metz, Christine N., Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Ciceri, Fabio, Barreiros, Lucila A., Dominguez-Garrido, Elena, Vidigal, Mateus, Zatz, Mayana, van de Beek, Diederik, Sahanic, Sabina, Tancevski, Ivan, Stepanovskyy, Yurii, Boyarchuk, Oksana, Nukui, Yoko, Tsumura, Miyuki, Vidaur, Loreto, Tangye, Stuart G., Burrel, Sonia, Duffy, Darragh, Quintana-Murci, Lluis, Klocperk, Adam, Kann, Nelli Y., Shcherbina, Anna, Lau, Yu-Lung, Leung, Daniel, Coulongeat, Matthieu, Marlet, Julien, Koning, Rutger, Reyes, Luis Felipe, Chauvineau-Grenier, Angélique, Venet, Fabienne, Monneret, Guillaume, Nussenzweig, Michel C., Arrestier, Romain, Boudhabhay, Idris, Baris-Feldman, Hagit, Hagin, David, Wauters, Joost, Meyts, Isabelle, Dyer, Adam H., Kennelly, Sean P., Bourke, Nollaig M., Halwani, Rabih, Sharif-Askari, Narjes Saheb, Dorgham, Karim, Sallette, Jérome, Mehlal Sedkaoui, Souad, AlKhater, Suzan, Rigo-Bonnin, Raúl, Morandeira, Francisco, Roussel, Lucie, Vinh, Donald C., Ostrowski, Sisse Rye, Condino-Neto, Antonio, Prando, Carolina, Bondarenko, Anastasiia, Spaan, András N., Gilardin, Laurent, Fellay, Jacques, Lyonnet, Stanislas, Bilguvar, Kaya, Lifton, Richard P., Mane, Shrikant, Anderson, Mark S., Boisson, Bertrand, Béziat, Vivien, Zhang, Shen-Ying, Andreakos, Evangelos, Hermine, Olivier, Pujol, Aurora, Peterson, Pärt, Mogensen, Trine H., Rowen, Lee, Mond, James, Debette, Stéphanie, de Lamballerie, Xavier, Duval, Xavier, Mentré, France, Zins, Marie, Soler-Palacin, Pere, Colobran, Roger, Gorochov, Guy, Solanich, Xavier, Susen, Sophie, Martinez-Picado, Javier, Raoult, Didier, Vasse, Marc, Gregersen, Peter K., Piemonti, Lorenzo, Rodríguez-Gallego, Carlos, Notarangelo, Luigi D., Su, Helen C., Kisand, Kai, Okada, Satoshi, Puel, Anne, Jouanguy, Emmanuelle, Rice, Charles M., Tiberghien, Pierre, Zhang, Qian, Cobat, Aurélie, Abel, Laurent, Casanova, Jean-Laurent, Bigio, Benedetta, de la Chapelle, Aliénor, Chen, Jie, Chrabieh, Maya, Liu, Dana, Nemirowskaya, Yelena, Cruz, Inés Marín, Materna, Marie, Pelet, Sophie, Seeleuthner, Yoann, Thibault, Chloé, Liu, Zhiyong, Abad, Jorge, Accordino, Giulia, Achille, Cristian, Aguilera-Albesa, Sergio, Aguiló-Cucurull, Aina, Özkan, Esra Akyüz, Darazam, Ilad Alavi, Roblero Albisures, Jonathan Antonio, Aldave, Juan C, Ramos, Miquel Alfonso, Khan, Taj Ali, Aliberti, Anna, Nadji, Seyed Alireza, Alkan, Gulsum, Alkhater, Suzan A., Allardet-Servent, Jerome, Allende, Luis M, Alonso-Arias, Rebeca, Alshahrani, Mohammed S, Alsina, Laia, Alyanakian, Marie-Alexandra, Borrero, Blanca Amador, Amoura, Zahir, Antolí, Arnau, Aubart, Mélodie, Auguet, Teresa, Avramenko, Iryna, Aytekin, Gökhan, Azot, Axelle, Bahram, Seiamak, Bajolle, Fanny, Baldanti, Fausto, Baldolli, Aurélie, Ballester, Maite, Feldman, Hagit Baris, Barrou, Benoit, Barzagh, Federica, Basso, Sabrina, Bayhan, Gulsum Iclal, Bezrodnik, Liliana, Bilbao, Agurtzane, Blanchard-Rohner, Geraldine, Blanco, Ignacio, Blandinières, Adeline, Blázquez-Gamero, Daniel, Bleibtreu, Alexandre, Bloomfield, Marketa, Bolivar-Prados, Mireia, Borghesi, Alessandro, Borie, Raphael, Botdhlo-Nevers, Elisabeth, Bousfiha, Ahmed A, Bousquet, Aurore, Boutolleau, David, Bouvattier, Claire, Bravais, Juliette, Briones, M. Luisa, Brunner, Marie-Eve, Bruno, Raffaele, Bueno, Maria Rita P, Bukhari, Huda, Bustamante, Jacinta, Cáceres Agra, Juan José, Capra, Ruggero, Carapito, Raphael, Carrabba, Maria, Casasnovas, Carlos, Caseris, Marion, Cassaniti, Irene, Castelle, Martin, Castelli, Francesco, de Vera, Martín Castillo, Castro, Mateus V, Catherinot, Emilie, Celik, Jale Bengi, Ceschi, Alessandro, Chalumeau, Martin, Charbit, Bruno, Cheng, Matthew P., Clavé, Père, Clotet, Bonaventura, Codina, Anna, Cohen, Yves, Comarmond, Cloé, Combes, Alain, Comoli, Patrizia, Corsico, Angelo G, Coşkuner, Taner, Cvetkovski, Aleksandar, Cyrus, Cyril, Danion, François, Darley, David Ross, Das, Vincent, Dauby, Nicolas, Dauger, Stéphane, De Munter, Paul, de Pontual, Loic, Dehban, Amin, Delplancq, Geoffroy, Demoule, Alexandre, Desguerre, Isabelle, Di Sabatino, Antonio, Diehl, Jean-Luc, Dobbelaere, Stephanie, Domínguez-Garrido, Elena, Dubost, Clément, Ekwall, Olov, Bozdemir, Şefika Elmas, Elnagdy, Marwa H, Emiroglu, Melike, Endo, Akifumi, Erdeniz, Emine Hafize, Aytekin, Selma Erol, Lasa, Maria Pilar Etxart, Euvrard, Romain, Fabio, Giovanna, Faivre, Laurence, Falck, Antonin, Fartoukh, Muriel, Faure, Morgane, Arquero, Miguel Fernandez, Ferrer, Ricard, Ferreres, Jose, Flores, Carlos, Francois, Bruno, Fumadó, Victoria, Fung, Kitty S C, Fusco, Francesca, Gagro, Alenka, Solis, Blanca Garcia, Gaussem, Pascale, Gayretli, Zeynep, Gil-Herrera, Juana, Gatineau, Audrey Giraud, Girona-Alarcón, Mònica, Cifuentes Godínez, Karen Alejandra, Goffard, Jean-Christophe, Gonzales, Nacho, Gonzalez-Granado, Luis I, González-Montelongo, Rafaela, Guerder, Antoine, Gülhan, Belgin, Gumucio, Victor Daniel, Hanitsch, Leif Gunnar, Gunst, Jan, Gut, Marta, Hadjadj, Jérôme, Hancerli, Selda, Hariyan, Tetyana, Hatipoglu, Nevin, Heppekcan, Deniz, Hernandez-Brito, Elisa, Ho, Po-ki, Holanda-Peña, María Soledad, Horcajada, Juan P, Hraiech, Sami, Humbert, Linda, Hung, Ivan F N, Iglesias, Alejandro D., Íñigo-Campos, Antonio, Jamme, Matthieu, Arranz, María Jesús, Jimeno, Marie-Thérèse, Jordan, Iolanda, Yüksek, Saliha Kanık, Kara, Yalcin Burak, Karahan, Aydın, Karbuz, Adem, Yasar, Kadriye Kart, Kasapcopur, Ozgur, Kashimada, Kenichi, Demirkol, Yasemin Kendir, Kido, Yasutoshi, Kizil, Can, Kılıç, Ahmet Osman, Koutsoukou, Antonia, Król, Zbigniew J., Ksouri, Hatem, Kuentz, Paul, Kwan, Arthur M C, Kwan, Yat Wah M, Kwok, Janette S Y, Lam, David S Y, Lampropoulou, Vicky, Lanternier, Fanny, Le Bourgeois, Fleur, Leo, Yee-Sin, Lopez, Rafael Leon, Levin, Michael, Levy, Michael, Lévy, Romain, Li, Zhi, Lilleri, Daniele, Lima, Edson Jose Adrian Bolanos, Linglart, Agnes, López-Collazo, Eduardo, Lorenzo-Salazar, José M., Louapre, Céline, Lubetzki, Catherine, Lung, Kwok-Cheung, Lye, David C, Magnone, Cinthia, Mansouri, Davood, Marchioni, Enrico, Marioli, Carola, Marjani, Majid, Marques, Laura, Pereira, Jesus Marquez, Martín-Nalda, Andrea, Pueyo, David Martínez, Marzana, Iciar, Mata-Martínez, Carmen, Mathian, Alexis, Matos, Larissa RB, Matthews, Gail V, Mayaux, Julien, McLaughlin-Garcia, Raquel, Meersseman, Philippe, Mège, Jean-Louis, Mekontso-Dessap, Armand, Melki, Isabelle, Meloni, Federica, Meritet, Jean-François, Merlani, Paolo, Akcan, Özge Metin, Mezidi, Mehdi, Migeotte, Isabelle, Millereux, Maude, Million, Matthieu, Mirault, Tristan, Mircher, Clotilde, Mirsaeidi, Mehdi, Mizoguchi, Yoko, Modi, Bhavi P, Mojoli, Francesco, Moncomble, Elsa, Melián, Abián Montesdeoca, Martinez, Antonio Morales, Morange, Pierre-Emmanuel, Mordacq, Clémence, Morelle, Guillaume, Mouly, Stéphane J, Muñoz-Barrera, Adrián, Nafati, Cyril, Nagashima, Shintaro, Nakagama, Yu, Neven, Bénédicte, Neves, João Farela, Ng, Lisa FP, Ng, Yuk-Yung, Nielly, Hubert, Medina, Yeray Novoa, Cuadros, Esmeralda Nuñez, Ocejo-Vinyals, J. 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Montse, Ruiz del Prado, Maria Yolanda, Ruiz-Rodriguez, Juan Carlos, Sabater-Riera, Joan, Saks, Kai, Salagianni, Maria, Sanchez, Oliver, Sánchez-Montalvá, Adrián, Sánchez-Ramón, Silvia, Schidlowski, Laire, Schluter, Agatha, Schmidt, Julien, Schmidt, Matthieu, Schuetz, Catharina, Schweitzer, Cyril E, Scolari, Francesco, Sediva, Anna, Seijo, Luis, Seminario, Analia Gisela, Seng, Piseth, Senoglu, Sevtap, Seppänen, Mikko, Llovich, Alex Serra, Shahrooei, Mohammad, Siguret, Virginie, Siouti, Eleni, Smadja, David M, Smith, Nikaia, Sobh, Ali, Soler, Catherine, Soler-Palacín, Pere, Sözeri, Betül, Stella, Giulia Maria, Stepanovskiy, Yuriy, Stoclin, Annabelle, Taccone, Fabio, Taupin, Jean-Luc, Tavernier, Simon J, Tello, Loreto Vidaur, Terrier, Benjamin, Thiery, Guillaume, Thorball, Christian, THORN, Karolina, Thumerelle, Caroline, Tipu, Imran, Tolstrup, Martin, Tomasoni, Gabriele, Toubiana, Julie, Alvarez, Josep Trenado, Troya, Jesús, Tsang, Owen T Y, Tserel, Liina, Tso, Eugene Y K, Tucci, Alessandra, Tüter Öz, Şadiye Kübra, Ursini, Matilde Valeria, Utsumi, Takanori, Uzunhan, Yurdagul, Vabres, Pierre, Valencia-Ramos, Juan, Van Den Rym, Ana Maria, Vandernoot, Isabelle, Velez-Santamaria, Valentina, Zuniga Veliz, Silvia Patricia, Vidigal, Mateus C, Viel, Sébastien, Vilain, Cédric, Vilaire-Meunier, Marie E, Villar-García, Judit, Vincent, Audrey, Vogt, Guillaume, Voiriot, Guillaume, Volokha, Alla, Vuotto, Fanny, Wauters, Els, Wu, Alan K L, Wu, Tak-Chiu, Yahşi, Aysun, Yesilbas, Osman, Yildiz, Mehmet, Young, Barnaby E, Yükselmiş, Ufuk, Zecca, Marco, Zuccaro, Valentina, Jens, Van Praet, Lambrecht, Bart N., Eva, Van Braeckel, Cédric, Bosteels, Levi, Hoste, Eric, Hoste, Bauters, Fré, De Clercq, Jozefien, Cathérine, Heijmans, Hans, Slabbynck, Leslie, Naesens, Florkin, Benoit, Boulanger, Cécile, Vanderlinden, Dimitri, Foti, Giuseppe, Bellani, Giacomo, Citerio, Giuseppe, Contro, Ernesto, Pesci, Alberto, Valsecchi, Maria Grazia, Cazzaniga, Marina, Danielson, Jeffrey J., Dobbs, Kerry, 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Maude, Paz, Pauline Caraux, Cervantes-Gonzalez, Minerva, Chair, Anissa, Chirouze, Catherine, Coelho, Alexandra, Cordel, Hugues, Couffignal, Camille, Couffin-Cadiergues, Sandrine, d’Ortenzio, Eric, De Montmollin, Etienne, Debard, Alexa, Debray, Marie-Pierre, Deplanque, Dominique, Descamps, Diane, Desvallée, Mathilde, Diallo, Alpha, Diouf, Alphonsine, Dorival, Céline, Dubos, François, Eloy, Philippine, Enouf, Vincent, Epaulard, Olivier, Esperou, Hélène, Esposito-Farese, Marina, Etienne, Manuel, Garot, Denis, Gault, Nathalie, Gaymard, Alexandre, Ghosn, Jade, Gigante, Tristan, Gilg, Morgane, Goehringer, François, Guedj, Jérémie, Hoctin, Alexandre, Hoffmann, Isabelle, Houas, Ikram, Hulot, Jean-Sébastien, Jaafoura, Salma, Kafif, Ouifiya, Kaguelidou, Florentia, Kali, Sabrina, Kerroumi, Younes, Khalil, Antoine, Khan, Coralie, Kimmoun, Antoine, Laine, Fabrice, Laouénan, Cédric, Laribi, Samira, Le, Minh, Le Bris, Cyril, Le Gac, Sylvie, Le Hingrat, Quentin, Le Mestre, Soizic, Le Nagard, Hervé, 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Petter, Bruhns, Pierre, Cerf-Bensussan, Nadine, Cumano, Ana, D’Enfert, Christophe, Deriano, Ludovic, Dillies, Marie-Agnès, Di Santo, James, Dromer, Françoise, Eberl, Gérard, Enninga, Jost, Gomperts-Boneca, Ivo, Hasan, Milena, Hedestam, Gunilla Karlsson, Hercberg, Serge, Ingersoll, Molly A, Lantz, Olivier, Kenny, Rose Anne, Ménager, Mickaël, Michel, Frédérique, Patin, Etienne, Pellegrini, Sandra, Rausell, Antonio, Rieux-Laucat, Frédéric, Rogge, Lars, Fontes, Magnus, Sakuntabhai, Anavaj, Schwartz, Olivier, Schwikowski, Benno, Shorte, Spencer, Tangy, Frédéric, Toubert, Antoine, Touvier, Mathilde, Ungeheuer, Marie-Noëlle, Zimmer, Christophe, Albert, Matthew L., Alavoine, Loubna, Behillil, Sylvie, Burdet, Charles, Charpentier, Charlotte, Dechanet, Aline, Ecobichon, Jean-Luc, Frezouls, Wahiba, Houhou, Nadhira, Lehacaut, Jonathan, Lucet, Jean-Christophe, Manchon, Pauline, Nouroudine, Mariama, Quintin, Caroline, Thy, Michael, van der Werf, Sylvie, Vignali, Valérie, Chahine, Abir, Waucquier, 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Joost, Vlaar, Alexander P.J., Al-Muhsen, Saleh, Al-Mulla, Fahd, Arias, Andrés A., Bogunovic, Dusan, Bolze, Alexandre, Bryceson, Yenan, Bustamante, Carlos D., Butte, Manish J., Chakravorty, Samya, Christodoulou, John, Constantinescu, Stefan N., Cooper, Megan A., Desai, Murkesh, Drolet, Beth A., El Baghdadi, Jamila, Espinosa-Padilla, Sara, Froidure, Antoine, Henrickson, Sarah E., Hsieh, Elena W.Y., Husebye, Eystein S., Imai, Kohsuke, Itan, Yuval, Jarvis, Erich D., Karamitros, Timokratis, Ku, Cheng-Lung, Ling, Yun, Lucas, Carrie L., Maniatis, Tom, Maródi, László, Milner, Joshua D., Mironska, Kristina, Ng, Lisa F.P., Novelli, Antonio, Novelli, Giuseppe, de Diego, Rebeca Perez, Renia, Laurent, Resnick, Igor, Sancho-Shimizu, Vanessa, Seppänen, Mikko R.J., Shahrooei, Mohammed, Slaby, Ondrej, Abou Tayoun, Ahmad, Ramaswamy, Sathishkumar, Turvey, Stuart E, Uddin, K M Furkan, Uddin, Mohammed J., von Bernuth, Horst, Zawadzki, Pawel, Nadif, Rachel, Goldberg, Marcel, Ozguler, Anna, Henny, Joseph, Lemonnier, Sylvie, Coeuret-Pellicer, Mireille, Le Got, Stéphane, Tzourio, Christophe, Dufouil, Carole, Soumaré, Aïcha, Lachaize, Morgane, Fievet, Nathalie, Flaig, Amandine, Martin, Fernando, Bonneaudeau, Brigitte, Cannet, Dorothée, Gallian, Pierre, Jeanne, Michel, Perroquin, Magali, Hamzeh-Cognasse, Hind

Publikováno v: Science Immunology
Science Immunology, 2021, 6 (62), pp.eabl4340. ⟨10.1126/sciimmunol.abl4340⟩
ISI atlas of science. Immunology 6 (2021). doi:10.1126/sciimmunol.abl4340
info:cnr-pdr/source/autori:Bastard P.; Gervais A.; Le Voyer T.; Rosain J.; Philippot Q.; Manry J.; Michailidis E.; Hoffmann H.-H.; Eto S.; Garcia-Prat M.; Bizien L.; Parra-Martinez A.; Yang R.; Haljasmagi L.; Migaud M.; Sarekannu K.; Maslovskaja J.; Prost N.D.; Tandjaoui-Lambiotte Y.; Luyt C.-E.; Amador-Borrero B.; Gaudet A.; Poissy J.; Morel P.; Richard P.; Cognasse F.; Troya J.; Trouillet-Assant S.; Belot A.; Saker K.; Garcon P.; Riviere J.G.; Lagier J.-C.; Gentile S.; Rosen L.B.; Shaw E.; Morio T.; Tanaka J.; Dalmau D.; Tharaux P.-L.; Sene D.; Stepanian A.; Megarbane B.; Triantafyllia V.; Fekkar A.; Heath J.R.; Franco J.L.; Anaya J.-M.; Sole-Violan J.; Imberti L.; Biondi A.; Bonfanti P.; Castagnoli R.; Delmonte O.M.; Zhang Y.; Snow A.L.; Holland S.M.; Biggs C.M.; Moncada-Velez M.; Arias A.A.; Lorenzo L.; Boucherit S.; Coulibaly B.; Anglicheau D.; Planas A.M.; Haerynck F.; Duvlis S.; Nussbaum R.L.; Ozcelik T.; Keles S.; Bousfiha A.A.; Bakkouri J.E.; Ramirez-Santana C.; Paul S.; Pan-Hammarstrom Q.; Hammarstrom L.; Dupont A.; Kurolap A.; Metz C.N.; Aiuti A.; Casari G.; Lampasona V.; Ciceri F.; Barreiros L.A.; Dominguez-Garrido E.; Vidigal M.; Zatz M.; Beek D.V.D.; Sahanic S.; Tancevski I.; Stepanovskyy Y.; Boyarchuk O.; Nukui Y.; Tsumura M.; Vidaur L.; Tangye S.G.; Burrel S.; Duffy D.; Quintana-Murci L.; Klocperk A.; Kann N.Y.; Shcherbina A.; Lau Y.-L.; Leung D.; Coulongeat M.; Marlet J.; Koning R.; Reyes L.F.; Chauvineau-Grenier A.; Venet F.; Monneret G.; Nussenzweig M.C.; Arrestier R.; Boudhabhay I.; Baris-Feldman H.; Hagin D.; Wauters J.; Meyts I.; Dyer A.H.; Kennelly S.P.; Bourke N.M.; Halwani R.; Sharif-Askari N.S.; Dorgham K.; Sallette J.; Sedkaoui S.M.; AlKhater S.; Rigo-Bonnin R.; Morandeira F.; Roussel L.; Vinh D.C.; Ostrowski S.R.; Condino-Neto A.; Prando C.; Bondarenko A.; Spaan A.N.; Gilardin L.; Fellay J.; Lyonnet S.; Bilguvar K.; Lifton R.P.; Mane S.; Anderson M.S.; Boisson B.; Beziat V.; Zhang S.-Y.; Andreakos E.; Hermine O.; Pujol A.; Peterson P.; Mogensen T.H.; Rowen L.; Mond J.; Debette S.; Lamballerie X.D.; Duval X.; Mentre F.; Zins M.; Soler-Palacin P.; Colobran R.; Gorochov G.; Solanich X.; Susen S.; Martinez-Picado J.; Raoult D.; Vasse M.; Gregersen P.K.; Piemonti L.; Rodriguez-Gallego C.; Notarangelo L.D.; Su H.C.; Kisand K.; Okada S.; Puel A.; Jouanguy E.; Rice C.M.; Tiberghien P.; Zhang Q.; Cobat A.; Abel L.; Casanova J.-L./titolo:Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths/doi:10.1126%2Fsciimmunol.abl4340/rivista:ISI atlas of science. Immunology/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:6
Science Immunology, 2021, 6 (62), ⟨10.1126/sciimmunol.abl4340⟩
Science immunology, 6(62):eabl4340. American Association for the Advancement of Science
Dipòsit Digital de la UB
Universidad de Barcelona
Science Immunology, American Association for the Advancement of Science, 2021, 6 (62), ⟨10.1126/sciimmunol.abl4340⟩
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Universidade de São Paulo (USP)
instacron:USP
Bastard, P, Gervais, A, Le Voyer, T, Rosain, J, Philippot, Q, Manry, J, Michailidis, E, Hoffmann, H H, Eto, S, Garcia-Prat, M, Bizien, L, Parra-Martínez, A, Yang, R, Haljasmägi, L, Migaud, M, Särekannu, K, Maslovskaja, J, Prost, N D, Tandjaoui-Lambiotte, Y, Luyt, C E, Amador-Borrero, B, Gaudet, A, Poissy, J, Morel, P, Richard, P, Cognasse, F, Troya, J, Trouillet-Assant, S, Belot, A, Saker, K, Garçon, P, Rivière, J G, Lagier, J C, Gentile, S, Rosen, L B, Shaw, E, Morio, T, Tanaka, J, Dalmau, D, Tharaux, P L, Sene, D, Stepanian, A, Megarbane, B, Triantafyllia, V, Fekkar, A, Heath, J R, Franco, J L, Anaya, J M, Mogensen, T H, Casanova, J L, The Milieu Intérieur Consortium, CoV-Contact Cohort, Amsterdam UMC Covid-19 Biobank Investigators, COVID Human Genetic Effort, CONSTANCES cohort, 3C-Dijon Study, Cerba HealthCare, Etablissement du Sang study group, HGID Lab, COVID Clinicians, COVID-STORM Clinicians, NIAID Immune Response to COVID Group, NH-COVAIR Study Group, Danish CHGE, Danish Blood Donor Study, St. James’s Hospital SARS CoV2 Interest group, French COVID Cohort Study Group & Imagine COVID Group 2021, ' Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths ', Science Immunology, vol. 6, no. 62, 4340 . https://doi.org/10.1126/sciimmunol.abl4340
Science immunology, vol. 6, no. 62, pp. eabl4340
French COVID Cohort Study Group, NIAID Immune Response to COVID Group, Danish CHGE, COVID Human Genetic Effort, HGID Lab, COVID-STORM Clinicians, NH-COVAIR Study Group, The Danish Blood Donor Study (DBDS), Imagine COVID-Group, The Milieu Intérieur Consortium, Amsterdam UMC Covid-19 Biobank, CONSTANCES cohort, 3C-Dijon Study, Cerba HealthCare, Etablissement du Sang study group, CoV-Contact Cohort, St James's Hospital, SARS CoV2 Interest group & COVID Clinicians 2021, ' Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths ', Science immunology, vol. 6, no. 62, eabl4340 . https://doi.org/10.1126/sciimmunol.abl4340
SCIENCE IMMUNOLOGY
COVID Human Genetic Effort, Imagine COVID-Group, Danish CHGE, CONSTANCES cohort, Etablissement du Sang study group, St James's Hospital, SARS CoV2 Interest group, 3C-Dijon Study, COVID Clinicians, CoV-Contact Cohort, NIAID Immune Response to COVID Group, Cerba HealthCare, French COVID Cohort Study Group, HGID Lab, COVID-STORM Clinicians, NH-COVAIR Study Group, The Danish Blood Donor Study (DBDS), The Milieu Intérieur Consortium & Amsterdam UMC Covid-19 Biobank 2021, ' Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths ', Science immunology, vol. 6, no. 62, eabl4340 . https://doi.org/10.1126/sciimmunol.abl4340, https://doi.org/10.1126/sciimmunol.abl4340
Digital.CSIC. Repositorio Institucional del CSIC
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Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 (coronavirus disease 2019) pneumonia but not in individuals wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9782ed7fd520b02e3e125e6fda82e43d
https://hal.science/hal-03358792/file/BPH_SI_2021_Bastard.pdf

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Autor: Zhang Q., Liu Z., Moncada-Velez M., Chen J., Ogishi M., Bigio B., Yang R., Arias A. A., Zhou Q., Han J. E., Ugurbil A. C., Zhang P., Rapaport F., Li J., Spaan A. N., Boisson B., Boisson-Dupuis S., Bustamante J., Puel A., Ciancanelli M. J., Zhang S. -Y., Beziat V., Jouanguy E., Abel L., Cobat A., Casanova J. -L., Bastard P., Korol C., Rosain J., Philippot Q., Chbihi M., Lorenzo L., Bizien L., Neehus A. -L., Kerner G., Seeleuthner Y., Manry J., Le Voyer T., Le Pen J., Schneider W. M., Razooky B. S., Hoffmann H. -H., Michailidis E., Rice C. M., Sabli I. K. D., Hodeib S., Sancho-Shimizu V., Bilguvar K., Ye J., Maniatis T., Bolze A., Zhang Y., Notarangelo L. D., Su H. C., Onodi F., Korniotis S., Karpf L., Soumelis V., Bonnet-Madin L., Amara A., Dorgham K., Gorochov G., Smith N., Duffy D., Moens L., Meyts I., Meade P., Garcia-Sastre A., Krammer F., Corneau A., Masson C., Schmitt Y., Schluter A., Pujol A., Khan T., Marr N., Fellay J., Roussel L., Vinh D. C., Shahrooei M., Alosaimi M. 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Publikováno v: Science (New York, N.Y.), 370 (6515
Science (New York, N.y.)
Science
Science, American Association for the Advancement of Science, 2020, 370 (6515), pp.eabd4570. ⟨10.1126/science.abd4570⟩
Science, 2020, 370 (6515), pp.eabd4570. ⟨10.1126/science.abd4570⟩
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Science, 370(6515):eabd4570. American Association for the Advancement of Science
SCIENCE
Science (New York, N.Y.) 370 (2020). doi:10.1126/science.abd4570
info:cnr-pdr/source/autori:Zhang Q.; Bastard P.; Liu Z.; Le Pen J.; Moncada-Velez M.; Chen J.; Ogishi M.; Sabli I.K.D.; Hodeib S.; Korol C.; Rosain J.; Bilguvar K.; Ye J.; Bolze A.; Bigio B.; Yang R.; Arias A.A.; Zhou Q.; Zhang Y.; Onodi F.; Korniotis S.; Karpf L.; Philippot Q.; Chbihi M.; Bonnet-Madin L.; Dorgham K.; Smith N.; Schneider W.M.; Razooky B.S.; Hoffmann H.-H.; Michailidis E.; Moens L.; Han J.E.; Lorenzo L.; Bizien L.; Meade P.; Neehus A.-L.; Ugurbil A.C.; Corneau A.; Kerner G.; Zhang P.; Rapaport F.; Seeleuthner Y.; Manry J.; Masson C.; Schmitt Y.; Schluter A.; Le Voyer T.; Khan T.; Li J.; Fellay J.; Roussel L.; Shahrooei M.; Alosaimi M.F.; Mansouri D.; Al-Saud H.; Al-Mulla F.; Almourfi F.; Al-Muhsen S.Z.; Alsohime F.; Al Turki S.; Hasanato R.; van de Beek D.; Biondi A.; Bettini L.R.; D'Angio' M.; Bonfanti P.; Imberti L.; Sottini A.; Paghera S.; Quiros-Roldan E.; Rossi C.; Oler A.J.; Tompkins M.F.; Alba C.; Vandernoot I.; Goffard J.-C.; Smits G.; Migeotte I.; Haerynck F.; Soler-Palacin P.; Martin-Nalda A.; Colobran R.; Morange P.-E.; Keles S.; Colkesen F.; Ozcelik T.; Yasar K.K.; Senoglu S.; Karabela SN.; Rodriguez-Gallego C.; Novelli G.; Hraiech S.; Tandjaoui-Lambiotte Y.; Duval X.; Laouenan C.; Snow A.L.; Dalgard C.L.; Milner J.D.; Vinh D.C.; Mogensen T.H.; Marr N.; Spaan A.N.; Boisson B.; Boisson-Dupuis S.; Bustamante J.; Puel A.; Ciancanelli M.J.; Meyts I.; Maniatis T.; Soumelis V.; Amara A.; Nussenzweig M.; Garcia-Sastre A.; Krammer F.; Pujol A.; Duffy D.; Lifton R.P.; Zhang S.-Y.; Gorochov G.; Beziat V.; Jouanguy E.; Sancho-Shimizu V.; Rice C.M.; Abel L.; Notarangelo L.D.; Cobat A.; Su H.C.; Casanova J.-L./titolo:Inborn errors of type I IFN immunity in patients with life-threatening COVID-19/doi:10.1126%2Fscience.abd4570/rivista:Science (New York, N.Y.)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:370
Science, vol. 370, no. 6515, pp. eabd4570
Zhang, Q, Bastard, P, Liu, Z, Le Pen, J, Moncada-Velez, M, Chen, J, Ogishi, M, Sabli, I K D, Hodeib, S, Korol, C, Rosain, J, Bilguvar, K, Ye, J, Bolze, A, Bigio, B, Yang, R, Arias, A A, Zhou, Q, Zhang, Y, Onodi, F, Korniotis, S, Karpf, L, Philippot, Q, Chbihi, M, Bonnet-Madin, L, Dorgham, K, Smith, N, Schneider, W M, Razooky, B S, Hoffmann, H H, Michailidis, E, Moens, L, Han, J E, Lorenzo, L, Bizien, L, Meade, P, Neehus, A L, Ugurbil, A C, Corneau, A, Kerner, G, Zhang, P, Rapaport, F, Seeleuthner, Y, Manry, J, Masson, C, Schmitt, Y, Schlüter, A, Li, J, Mogensen, T H, Casanova, J L, COVID-STORM Clinicians, COVID Clinicians, Imagine COVID Group, French COVID Cohort Study Group, CoV-Contact Cohort, Amsterdam UMC Covid-19 Biobank, COVID Human Genetic Effort & NIAID-USUHS/TAGC COVID Immunity Group 2020, ' Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 ', Science, vol. 370, no. 6515 . https://doi.org/10.1126/science.abd4570
Dipòsit Digital de la UB
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Zhang, Q, Amsterdam UMC Covid-19 Biobank, COVID Human Genetic Effort, NIAID-USUHS/TAGC COVID Immunity Group, COVID Clinicians, Imagine COVID Group, COVID-STORM Clinicians, COVID-STORM Clinicians, French COVID Cohort Study Group & CoV-Contact Cohort 2020, ' Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 ', Science, vol. 370, no. 6515, eabd4570 . https://doi.org/10.1126/science.abd4570
Digital.CSIC. Repositorio Institucional del CSIC

COVID-STORM Clinicians Giuseppe Foti1, Giacomo Bellani 1, Giuseppe Citerio1, Ernesto Contro1, Alberto Pesci2, Maria Grazia Valsecchi3, Marina Cazzaniga4 1Department of Emergency, Anesthesia and Intensive Care, School of Medicine and Surgery, Universi

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http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/314332

KADA POSUMNJATI NA AUTOINFLAMATORNU BOLEST?

Autor: Mario Šestan, Marija Jelušić

Publikováno v: Reumatizam
Volume 67
Issue 1

Autoinflammatory diseases are clinical disorders caused by a deficiency or dysregulation of innate immunity, characterized by recurrent or persistent inflammation (increased levels of acute phase reactants) and the absence of a primary pathogenic rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______951::300bbcd93d4b78c5f9ee8417a4474006
https://hrcak.srce.hr/file/360829

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Autor: Alex K. Shalek, Kun Zhang, Christopher W. Peterson, Orit Rosen, Alison Yu, Robert Lafyatis, Samuel W. Kazer, Oliver Eickelberg, Sarah A. Teichmann, Mauricio Rojas, Martijn C. Nawijn, Colin D. Bingle, Thu Elizabeth Duong, Manuel Garber, Magali Plaisant, Philana Ling Lin, Christine S. Falk, Jennifer P. Wang, Xin Sun, Hengqi Betty Zheng, G. James Gatter, Sarah K. Nyquist, Malte Kühnemund, Joachim L. Schultze, Mark A. Krasnow, Maarten van den Berge, Yan Xu, Samuel J. Allon, Daniel F. Dwyer, Peter Horvath, Benjamin Doran, Brian M. Lin, Herbert B. Schiller, Blake M. Hauser, Fabian J. Theis, Avrum Spira, Paul A. Reyfman, Hans-Peter Kiem, Shaina L. Carroll, Zhiru Guo, Douglas P. Shepherd, Michael von Papen, Ian M. Mbano, Michael Farzan, Daniel Lingwood, JoAnne L. Flynn, Christoph Muus, Dana Pe'er, Stephen R. Quake, Travis K. Hughes, Sarah M. Fortune, Sten Linnarson, Chase J. Taylor, Tanya M. Laidlaw, Emma L. Rawlins, Bonnie Berger, Ashraf S. Yousif, Joakim Lundeberg, Jeffrey A. Whitsett, Ian A. Glass, Delphine Gras, Max A. Seibold, Jay Rajagopal, Jared Feldman, Victor Tkachev, Benjamin E. Mead, Joseph E. Powell, Aviv Regev, Alasdair Leslie, Robert W. Finberg, Yuming Cao, Jennifer M.S. Sucre, Marko Vukovic, Scott B. Snapper, Vincent N. Miao, Naftali Kaminski, Laure-Emmanuelle Zaragosi, Caylin G. Winchell, Faith Taliaferro, Marko Nikolic, Ilias Angelidis, Leslie S. Kean, Lucrezia Colonna, Kathleen M. Buchheit, Aaron G. Schmidt, Ramnik J. Xavier, Tushar J. Desai, Marc H. Wadsworth, Joshua A. Boyce, Alexander M. Tsankov, Nora A. Barrett, Pascal Barbry, Muzlifah Haniffa, Heiko Adler, Alvis Brazma, Hannah P. Gideon, Meshal Ansari, Jason R. Spence, Avinash Waghray, Constantine N. Tzouanas, Jose Ordovas-Montanes, Jonathan A. Kropski, Nicholas E. Banovich, Purushothama Rao Tata, Kerstin B. Meyer, Christos Samakovlis, Haeock Lee, Carly G. K. Ziegler, Alexander V. Misharin, Deborah T. Hung, Sylvie Leroy, Julia Bals, Vanessa Mitsialis, Kourosh Saeb-Parsy

Publikováno v: Cell
Cell, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell, Elsevier, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell 181, 1016-1035 (2020)
Elsevier
Cell, 181(5), 1016-1035.e19. CELL PRESS

Summary There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS-CoV-2 spike (S) protein binds angiotensin-converting enzyme 2 (ACE2),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727543612f7db162539d6c42ca832836
https://doi.org/10.1016/j.cell.2020.04.035

Tumor necrosis factormediated survival of CD169+ cells promotes immune activation during vesicular stomatitis virus infection

Autor: Nico van Rooijen, Andreas Kloetgen, Tak W. Mak, Prashant V. Shinde, Mathias Heikenwalder, Namir Shaabani, Stefanie Scheu, Jürgen Ruland, Sukumar Namineni, Yuan Zhuang, Aleksandra A. Pandyra, Dirk Brenner, Mirko Trilling, Nicolás Bellora, Mareike Doerrenberg, Arndt Borkhardt, Klaus Pfeffer, Percy A. Knolle, Philipp A. Lang, Haifeng C. Xu, Nadine Honke, Vitaly I. Pozdeev, Sathish Kumar Maney, Paul R. Crocker, Masato Tanaka, Sujitha Duggimpudi, Dieter Häussinger, Jessica I. Hoell, Karl S. Lang

Publikováno v: Shinde, P V, Xu, H C, Maney, S K, Kloetgen, A, Namineni, S, Zhuang, Y, Honke, N, Shaabani, N, Bellora, N, Doerrenberg, M, Trilling, M, Pozdeev, V I, van Rooijen, N, Scheu, S, Pfeffer, K, Crocker, P R, Tanaka, M, Duggimpudi, S, Knolle, P, Heikenwalder, M, Ruland, J R, Mak, T W, Brenner, D, Pandyra, A A, Hoell, J I, Borkhardt, A, Häussinger, D, Lang, K S & Lang, P A 2018, ' Tumor necrosis factormediated survival of CD169+ cells promotes immune activation during vesicular stomatitis virus infection ', Journal of Virology, vol. 92, no. 3, e01637-17 . https://doi.org/10.1128/JVI.01637-17
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Shinde, P V, Xu, H C, Maney, S K, Kloetgen, A, Namineni, S, Zhuang, Y, Honke, N, Shaabani, N, Bellora, N, Doerrenberg, M, Trilling, M, Pozdeev, V I, van Rooijen, N, Scheu, S, Pfeffer, K, Crocker, P R, Tanaka, M, Duggimpudi, S, Knolle, P, Heikenwalder, M, Ruland, J, Mak, T W, Brenner, D, Pandyra, A A, Hoell, J I, Borkhardt, A, Häussinger, D, Lang, K S & Lang, P A 2018, ' Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection ', Journal of Virology, vol. 92, no. 3, e01637-17, pp. e01637-17 . https://doi.org/10.1128/JVI.01637-17
Journal of virology
J. Virol. 92, DOI: 10.1128/JVI.01637-17 (2017)
Journal of Virology, 92(3):e01637-17. American Society for Microbiology
Journal of Virology

Innate immune activation is essential to mount an effective antiviral response and to prime adaptive immunity. Although a crucial role of CD169+ cells during vesicular stomatitis virus (VSV) infections is increasingly recognized, factors regulating C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad07de59d567d0c28c95469b650ca30
https://research.vumc.nl/en/publications/96c9f1d3-e363-4e3d-928c-33fea37bf29a