Zobrazeno 1 - 10
of 1 062
pro vyhledávání: '"Intercalated disc"'
Autor:
Adams, William Patrick
Sudden cardiac death is largely attributable to sudden onset ventricular arrhythmias. Alterations in cardiac conduction, particularly the slowing of conduction velocity is one major factor in arrhythmogenesis. By understanding the mechanisms and fact
Externí odkaz:
https://hdl.handle.net/10919/119281
Autor:
Rebecca Schönmehl, Daniel H. Mendelsohn, Lina Winter, Steffen Pabel, Tanja Niedermair, Katja Evert, Wing-Hoi Cheung, Ronald Man Yeung Wong, Volker H. Schmitt, Karsten Keller, Friedrich Barsch, Alexander Dietl, Jan F. Gummert, René Schramm, Samuel Sossalla, Christoph Brochhausen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7644 (2024)
Background: Mitochondria play a crucial role in adapting to fluctuating energy demands, particularly in various heart diseases. This study investigates mitochondrial morphology near intercalated discs in left ventricular (LV) heart tissues, comparing
Externí odkaz:
https://doaj.org/article/03b26e33f7474ec7b0672325fe2460dc
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6208 (2024)
Arrhythmogenic cardiomyopathy (ACM) is a rare genetic cardiac disease characterized by the progressive substitution of myocardium with fibro-fatty tissue. Clinically, ACM shows wide variability among patients; symptoms can include syncope and ventric
Externí odkaz:
https://doaj.org/article/3e5d53c76eae43019adcee89eadbc354
Akademický článek
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Autor:
Giuseppina Mastrototaro, Pierluigi Carullo, Jianlin Zhang, Beatrice Scellini, Nicoletta Piroddi, Simona Nemska, Maria Carmela Filomena, Simone Serio, Carol A Otey, Chiara Tesi, Fabian Emrich, Wolfgang A Linke, Corrado Poggesi, Simona Boncompagni, Marie-Louise Bang
Publikováno v:
eLife, Vol 12 (2023)
Palladin (PALLD) belongs to the PALLD/myopalladin (MYPN)/myotilin family of actin-associated immunoglobulin-containing proteins in the sarcomeric Z-line. PALLD is ubiquitously expressed in several isoforms, and its longest 200 kDa isoform, predominan
Externí odkaz:
https://doaj.org/article/48822b874b00423185ecb43b08a61552
Autor:
Francine Parker, Anna A. S. Tang, Brendan Rogers, Glenn Carrington, Cris dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human heart is important in understanding how the heart becomes less effective at contraction. Here
Externí odkaz:
https://doaj.org/article/cc6a0c4d5c4f4d3485748c72de4d581d
Autor:
Yue Yin, Xinping Xu, Dayan Li, Binwei Yao, Haoyu Wang, Li Zhao, Hui Wang, Ji Dong, Jing Zhang, Ruiyun Peng
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12533 (2023)
The heart is one of the major organs affected by microwave radiation, and these effects have been extensively studied. Previous studies have shown that microwave-radiation-induced heart injury might be related to the abnormal expression and distribut
Externí odkaz:
https://doaj.org/article/8121e4ebff544a488e4846c65b707f5c
Autor:
Willem B. van Ham, Esmeralda E. M. Meijboom, Merel L. Ligtermoet, Peter G. J. Nikkels, Toon A. B. van Veen
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 8, p 354 (2023)
The development of the normal human heart, ranging from gestational age to the mature adult heart, relies on a very delicate and timely orchestrated order of processes. One of the most striking alterations in time is the gradual extinction of the abi
Externí odkaz:
https://doaj.org/article/54e18138646b4512814ae4be390912db
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11726 (2023)
The intercalated disk is a cardiac specific structure composed of three main protein complexes—adherens junctions, desmosomes, and gap junctions—that work in concert to provide mechanical stability and electrical synchronization to the heart. Eac
Externí odkaz:
https://doaj.org/article/4f12a9981636458dbe4b3a54133a5a73
Publikováno v:
Applied Microscopy, Vol 50, Iss 1, Pp 1-9 (2020)
Abstract Arthropods have an open circulatory system with a simple tubular heart, so it has been estimated that the contractile pumping structure of the cardiac muscle will be less efficient than that of vertebrates. Nevertheless, certain arthropods a
Externí odkaz:
https://doaj.org/article/f564d2a205824ab9bf28a3b39b5464b3