Zobrazeno 1 - 10
of 1 394
pro vyhledávání: '"Interactomics"'
Autor:
Jinwen Chen
Publikováno v:
Crop Design, Vol 3, Iss 4, Pp 100078- (2024)
Behaviour, morphology and responses to stimuli in biological systems are determined by the genetic information of different types of biomolecules and the interactions between them. Comparative interactomics, the discipline devoted in comparing two or
Externí odkaz:
https://doaj.org/article/52c9541ab9bd47ddb2dbb182da58fa28
Autor:
Shaoshuai Xie, Leila Saba, Hua Jiang, Omar R Bringas, Mehrnoosh Oghbaie, Luciano Di Stefano, Vadim Sherman, John LaCava
Publikováno v:
BioTechniques, Vol 76, Iss 4, Pp 145-152 (2024)
Immunoprecipitation (IP) coupled with mass spectrometry effectively maps protein–protein interactions when genome-wide, affinity-tagged cell collections are used. Such studies have recorded significant portions of the compositions of physiological
Externí odkaz:
https://doaj.org/article/cd3df74433d04441b4920c65549a30d8
Autor:
Boglarka Zambo, Evelina Edelweiss, Bastien Morlet, Luc Negroni, Matyas Pajkos, Zsuzsanna Dosztanyi, Soren Ostergaard, Gilles Trave, Jocelyn Laporte, Gergo Gogl
Publikováno v:
eLife, Vol 13 (2024)
Truncation of the protein-protein interaction SH3 domain of the membrane remodeling Bridging Integrator 1 (BIN1, Amphiphysin 2) protein leads to centronuclear myopathy. Here, we assessed the impact of a set of naturally observed, previously uncharact
Externí odkaz:
https://doaj.org/article/f5c33ef1efd744989b95c329d4a4ad45
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32579- (2024)
Aims: Alveolar epithelial barrier integrity is essential for lung homeostasis. Na, K-ATPase β1 subunit (ATP1B1) involves alveolar edema fluid clearance and alveolar epithelial barrier stability. However, the underlying molecular mechanism of ATP1B1
Externí odkaz:
https://doaj.org/article/f88ee2fc466a437d99781319481b6b8b
Autor:
Neelam Younas, Saima Zafar, Tayyaba Saleem, Leticia Camila Fernandez Flores, Abrar Younas, Matthias Schmitz, Inga Zerr
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background Aberrant stress granules (SGs) are emerging as prime suspects in the nucleation of toxic protein aggregates. Understanding the molecular networks linked with aggregation-prone proteins (prion protein, synuclein, and tau) under str
Externí odkaz:
https://doaj.org/article/ae784e4048cf4683997f67b8926ae885
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/52edd5c0a0fd44a888a058db32dbd1b5
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 541 (2024)
This study presents the interaction with the human host metabolism of SARS-CoV-2 ORF7b protein (43 aa), using a protein–protein interaction network analysis. After pruning, we selected from BioGRID the 51 most significant proteins among 2753 proven
Externí odkaz:
https://doaj.org/article/ed470bd5109c4753a78b43db619e6d88
Publikováno v:
Guangdong nongye kexue, Vol 49, Iss 11, Pp 86-95 (2022)
Protein interactomics is a cutting-edge technology to identify and quantify the interaction of proteins with other metabolites or molecules like proteins, which has been an important part of plant systems biology and multi-omics research. In recent y
Externí odkaz:
https://doaj.org/article/3edc23a7bf02475cb616fdc15c571eef
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
The pathogenicity of L. pneumophila, the causative agent of Legionnaires’ disease, depends on an arsenal of interacting proteins. Here we describe how surface-associated and secreted virulence factors of this pathogen interact with each other or ta
Externí odkaz:
https://doaj.org/article/f86386d637444cc9b513cb9d81b4caf9
SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation
Autor:
Zivojin Jevtic, Vittoria Matafora, Francesca Casagrande, Fabio Santoro, Saverio Minucci, Massimilliano Garre’, Milad Rasouli, Olaf Heidenreich, Giovanna Musco, Jürg Schwaller, Angela Bachi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Acute myeloid leukemia (AML) is characterized by accumulation of aberrantly differentiated hematopoietic myeloid progenitor cells. The karyotyping-silent NUP98-NSD1 fusion is a molecular hallmark of pediatric AML and is associated
Externí odkaz:
https://doaj.org/article/de8b70eb51e347ddba8b9d02fc7d69e4