Zobrazeno 1 - 10
of 1 782
pro vyhledávání: '"Interaction prediction"'
Autor:
Sarah Krautwurst, Kevin Lamkiewicz
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 4036-4046 (2024)
RNA-protein interactions (RPIs) are crucial for accurately operating various processes in and between organisms across kingdoms of life. Mutual detection of RPI partner molecules depends on distinct sequential, structural, or thermodynamic features,
Externí odkaz:
https://doaj.org/article/2f6fd3422f254fb9b8f0abf4ffcb4373
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3030-3039 (2024)
Current medical research has been demonstrating the roles of miRNAs in a variety of cellular mechanisms, lending credence to the association between miRNA dysregulation and multiple diseases. Understanding the mechanisms of miRNA is critical for deve
Externí odkaz:
https://doaj.org/article/3eca48283a8d4b4786dfaf8899d008ab
Autor:
Bruno Rafael Florentino, Robson Parmezan Bonidia, Natan Henrique Sanches, Ulisses N. da Rocha, André C.P.L.F. de Carvalho
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2267-2276 (2024)
Machine Learning (ML) algorithms have been important tools for the extraction of useful knowledge from biological sequences, particularly in healthcare, agriculture, and the environment. However, the categorical and unstructured nature of these seque
Externí odkaz:
https://doaj.org/article/79c8210b24c14206b7d2f4cd1411df46
Autor:
Sina Abdollahi, Darius P. Schaub, Madalena Barroso, Nora C. Laubach, Wiebke Hutwelker, Ulf Panzer, S.øren W. Gersting, Stefan Bonn
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-27 (2024)
Abstract The evaluation of compound-target interactions (CTIs) is at the heart of drug discovery efforts. Given the substantial time and monetary costs of classical experimental screening, significant efforts have been dedicated to develop deep learn
Externí odkaz:
https://doaj.org/article/380b64076bc34143b62f43f36095c6fa
Autor:
YaPing Wang, ZhiXiang Yin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The study of drug–target interaction plays an important role in the process of drug development. The subject of DTI forecasting has advanced significantly in the last several years, yielding numerous significant research findings and metho
Externí odkaz:
https://doaj.org/article/df5b26ac34ea4eb588b41dc3d0c1c82e
Autor:
Sagar Adhurya, Young‐Seuk Park
Publikováno v:
Methods in Ecology and Evolution, Vol 15, Iss 7, Pp 1247-1260 (2024)
Abstract This gap in knowledge regarding ecological interactions has prompted the development of various predictive approaches. Traditionally, ecological interactions have been inferred using traits. However, the lack of trait information for numerou
Externí odkaz:
https://doaj.org/article/cf82de020bb7475fbebda113942342e8
Publikováno v:
AIMS Neuroscience, Vol 11, Iss 2, Pp 203-211 (2024)
Obsessive-compulsive disorder (OCD) is a chronic psychiatric disease in which patients suffer from obsessions compelling them to engage in specific rituals as a temporary measure to alleviate stress. In this study, deep learning-based methods were us
Externí odkaz:
https://doaj.org/article/5c6a251affc24b5c900935e12fb05141
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Protein-protein interactions (PPIs) hold significant importance in biology, with precise PPI prediction as a pivotal factor in comprehending cellular processes and facilitating drug design. However, experimental determination of P
Externí odkaz:
https://doaj.org/article/ad204205500b40cebe21fee86734ac2f
Autor:
Meng, Li a, 1, He, Yunfei a, 1, Sun, Chenyuan a, Huang, Lishan a, Hu, Taizhang b, Yang, Fei a, ⁎
Publikováno v:
In Neural Networks January 2025 181
Publikováno v:
In Expert Systems With Applications 10 March 2025 264