Week 26 results from the PaTH Forward Open-Label Extension Trial Support TransCon PTH as a potential hormone replacement therapy for patients with hypoparathyroidism

Autor: Lars Rejnmark, Peter Schwarz, Mishaela Rubin, Tamara Vokes, Bart Clarke, Intekhab Ahmed, Andrea Palermo, Claudio Marcocci, Uberto Pagotto, Erik Eriksen, Sanchita Mourya, Denka Markova, Susanne Pihl, Michael Beckert, Aimee Shu, Aliya Khan

Publikováno v: Bone Reports, Vol 14, Iss , Pp 100773- (2021)

Externí odkaz: https://doaj.org/article/00197ce1c16c4b7c8aee8014a1eb9052

PaTH Forward:A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of TransCon PTH in Adult Hypoparathyroidism

Autor: Peter Schwarz, Denka Markova, Alden Smith, Sanchita Mourya, Lars Rejnmark, Aimee D Shu, Intekhab Ahmed, David B Karpf, Tamara Vokes, Aliya Khan, Claudio Marcocci, Bart L. Clarke, Meryl Brod, Erik Fink Eriksen, Mishaela R. Rubin, Susanne Pihl, Uberto Pagotto, Andrea Palermo, Lorenz C. Hofbauer

Publikováno v: Khan, A A, Rejnmark, L, Rubin, M, Schwarz, P, Vokes, T, Clarke, B, Ahmed, I, Hofbauer, L, Marcocci, C, Pagotto, U, Palermo, A, Eriksen, E, Brod, M, Markova, D, Smith, A, Pihl, S, Mourya, S, Karpf, D B & Shu, A D 2022, ' PaTH Forward : A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of TransCon PTH in Adult Hypoparathyroidism ', Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 1, pp. E372-E385 . https://doi.org/10.1210/clinem/dgab577
The Journal of Clinical Endocrinology and Metabolism

Context Hypoparathyroidism is characterized by insufficient levels of parathyroid hormone (PTH). TransCon PTH is an investigational long-acting prodrug of PTH(1-34) for the treatment of hypoparathyroidism. Objective This work aimed to investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c2cf0348e82835f0ff0a5670103b0b
https://curis.ku.dk/portal/da/publications/path-forward(e72390ee-4276-41d2-8b23-5d120efae605).html

External validation of 4C ISARIC mortality score in the setting of a Saudi Arabian ICU. Retrospective study

Autor: Saima A. Shahzad, Huda Mhawish, Zohdy A. Saif, Waqas Mahmood, Mohamed Gharba, Shahzad A. Mumtaz, Intekhab Ahmed, Majd M. Abdulmowla, Mohammed Alodat, Ahmed Mady, Waleed Tharwat Aletreby

COVID-19 pandemic has burdened healthcare systems, necessitating the development of mortality prediction scores to guide clinical decisions and resource allocation. 4C ISARIC mortality score was developed and validated on a British cohort.ObjectivesE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c05985c2098207b13d3e425bc96ffa28
https://doi.org/10.1101/2021.08.16.21262104

TransCon PTH as a potential hormone replacement therapy for patients with hypoparathyroidism: PaTH forward open-label extension trial week 26 results

Autor: Aimee Shu, Aliya Khan, Andrea Palermo, Denka Markova, Michael Beckert, Cristina Pagotto, Lars Rejnmark, Erik Fink Eriksen, Mishaela R. Rubin, Tamara Vokes, Intekhab Ahmed, Sanchita Mourya, Claudio Marcocci, Peter Schwarz, Susanne Pihl, Bart L Clarke

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d5c3ff23a69587797f964ce2d63ca94
https://doi.org/10.1530/endoabs.73.oc6.6

Efficacy and safety with TransCon PTH for adults with hypoparathyroidism through week 84 in the PaTH Forward trial

Autor: Lorenz Hofbauer, Aliya Khan, Peter Schwarz, Mishaela Rubin, Tamara Vokes, Bart Clarke, Intekhab Ahmed, Andrea Palermo, Uberto Pagotto, Claudio Marcocci, Erik Eriksen, Denka Markova, John Le, Susanne Pihl, Lisa Vansaghi, Christopher Sibley, Aimee Shu, Lars Rejnmark

Publikováno v: Bone Reports. 16:101231

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2180006276f4bdbb2c89f47abb9f4e14
https://doi.org/10.1016/j.bonr.2022.101231