Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Integrins/metabolism"'
Autor:
Karim Bouzakri, Katharina Rickenbach, Caroline Arous, Michel Pinget, Bernhard Wehrle-Haller, Maria L. Mizgier
Publikováno v:
Journal of Biological Chemistry, Vol. 295, No 49 (2020) pp. 16510-16528
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Elevated levels of fasting insulin release and insufficient glucose-stimulated insulin secretion (GSIS) are hallmarks of diabetes. Studies have established cross-talk between integrin signaling and insulin activity, but more details of how integrin-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4063a6b9e04781fc7fe5d6ec0c61ec14
https://doi.org/10.1074/jbc.ra120.012957
https://doi.org/10.1074/jbc.ra120.012957
Publikováno v:
Seminars in Cancer Biology
Seminars in cancer biology, 62
Seminars in cancer biology, 62
The tumor microenvironment (TME) is a complex meshwork of extracellular matrix (ECM) macromolecules filled with a collection of cells including cancer-associated fibroblasts (CAFs), blood vessel associated smooth muscle cells, pericytes, endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baaa1409d6eb1ab3f3b6133f9a7a5a00
https://doi.org/10.1016/j.semcancer.2019.08.004
https://doi.org/10.1016/j.semcancer.2019.08.004
Autor:
Ana Margarida Moreira, Joana Figueiredo, Soraia Melo, Patrícia Carneiro, Maria Sofia Fernandes, Joana Pereira, Raquel Seruca
Publikováno v:
Cells, Vol 9, Iss 2, p 394 (2020)
CIÊNCIAVITAE
Cells
CIÊNCIAVITAE
Cells
The extracellular matrix (ECM) is a dynamic and highly organized tissue structure, providing support and maintaining normal epithelial architecture. In the last decade, increasing evidence has emerged demonstrating that alterations in ECM composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0419f98414c491e6dde8124efa8bcd28
https://www.mdpi.com/2073-4409/9/2/394
https://www.mdpi.com/2073-4409/9/2/394
Publikováno v:
Chemistry : A European Journal, 24(61), 16445-16451. Wiley-VCH Verlag
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry (Weinheim an Der Bergstrasse, Germany)
The cellular uptake of self‐assembled biological and synthetic matter results from their multicomponent properties. However, the interplay of the building block composition of self‐assembled materials and uptake mechanisms urgently requires addre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc36fb76806f58601a0a76196b4905e
https://doi.org/10.1002/chem.201804045
https://doi.org/10.1002/chem.201804045
Autor:
Anja Seckinger, Giorgio Mori, Volker Martin, Anna Luise Grab, Elisabetta Ada Cavalcanti-Adam, Slobodan Vukicevic, Francesca Posa, Dirk Hose
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and signaling responses which regulate the transdifferentiation of myobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585faf31fe1d433826775658439c7746
Autor:
Coert Margadant, Martijn A. Nolte
Publikováno v:
Blood. 135(1)
Integrins are a large family of heterodimeric cell surface receptors that bind prototypic ligands on neighboring cells or in the extracellular matrix. Numerous studies have revealed key roles for platelet and leukocyte integrins in adhesion and migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a596194dd88301aba8e6644cd13dfae
https://pubmed.ncbi.nlm.nih.gov/31730155
https://pubmed.ncbi.nlm.nih.gov/31730155
Autor:
Severine Tabone-Eglinger, David Boettiger, Nicole Aebischer, Monique Wehrle-Haller, Bernhard Wehrle-Haller, Zuleika Calderin-Sollet, Marie-Claude Jacquier, Perrine Pinon
Publikováno v:
The FASEB Journal
FASEB Journal, Vol. 28, No 10 (2014) pp. 4441-4456
FASEB Journal, Vol. 28, No 10 (2014) pp. 4441-4456
Kit ligand (KitL) and its tyrosine kinase receptor c-kit are critical for germ cells, melanocytes, mastocytes, and hematopoietic stem cells. Alternative splicing of KitL generates membrane-bound KitL (mb-KitL) or soluble KitL, providing survival or c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c44115bee5641478f31487eead691d
https://doi.org/10.1096/fj.14-249425
https://doi.org/10.1096/fj.14-249425
Autor:
Renske J. de Jong, Barbara Walzog, Christian Weber, Robert Pick, Almudena Ortega-Gomez, Patricia Lemnitzer, Jochen Grommes, Wolfgang Siess, Remco T. A. Megens, Janina Jamasbi, Christoph Scheiermann, Alexander Zarbock, Jan Rossaint, Janine Brauner, Maik Drechsler, Jessica Tilgner, Oliver Soehnlein, Yvonne Döring, Christine T. N. Pham, Melanie Salvermoser
Publikováno v:
Circulation, Vol. 134, No 16 (2016) pp. 1176-1188
Circulation, 134(16), 1176-1188. Lippincott Williams and Wilkins
Circulation, 134(16), 1176-1188. LIPPINCOTT WILLIAMS & WILKINS
Circulation, 134(16), 1176-1188. Lippincott Williams and Wilkins
Circulation, 134(16), 1176-1188. LIPPINCOTT WILLIAMS & WILKINS
Background: Therapeutic targeting of arterial leukocyte recruitment in the context of atherosclerosis has been disappointing in clinical studies. Reasons for such failures include the lack of knowledge of arterial-specific recruitment patterns. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b977fcd07ec8f1feeb5c627967349063
https://archive-ouverte.unige.ch/unige:111932
https://archive-ouverte.unige.ch/unige:111932
Autor:
Anastase Spiliopoulos, Marie-Marthe Philippeaux, John Robert, Jean-Pierre Bargetzi, Jean-Claude Pache, Jacques Mauël
Publikováno v:
European Journal of Cell Biology, Vol. 88, No 4 (2009) pp. 243-256
Freshly isolated, starch-elicited mouse peritoneal macrophages (Mø) attached very efficiently to type I collagen in vitro, if collagen molecules were arranged in ordered supra-molecular assemblies corresponding to the precursor native fibrils. After
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae218dff119058d1765c8ac5a4e3ca5f
https://doi.org/10.1016/j.ejcb.2008.11.002
https://doi.org/10.1016/j.ejcb.2008.11.002
Autor:
Yves Lepelletier, Mireille Dardenne, Ana Cristina Martins de Almeida Nogueira, Olivier Hermine, Wilson Savino, Salete Smaniotto, Déa Maria Serra Villa-Verde, Réda Hadj-Slimane
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104, pp.5545-5550
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104, pp.5545-5550. ⟨10.1073/pnas.0700705104⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104, pp.5545-5550
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104, pp.5545-5550. ⟨10.1073/pnas.0700705104⟩
It is largely established that molecules first discovered in the nervous system are also found in the immune system. Neuropilin-1 (NP-1) was initially identified to mediate semaphorin-induced chemorepulsion during brain development and is also involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632e6d9457a82a7401f9dfc62b512b01
https://doi.org/10.1073/pnas.0700705104
https://doi.org/10.1073/pnas.0700705104