Cellular Adhesion : Molecular Definition to Therapeutic Potential

Autor: Brian W. Metcalf, Barbara J. Dalton, George Poste, Judy Schatz

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation

Autor: Boris Hinz, Mercedes Costell, Elisabeth Génot, Franco Klingberg, Thomas M. Quinn, Stellar Boo, Benjamin A. Alman, Anne Koehler, Melissa L. Chow, Lara Buscemi

Publikováno v: Klingberg, Franco Chow, Melissa L. Koehler, Anne Boo, Stellar Buscemi, Lara Quinn, Thomas M. Costell Rosselló, Mercedes Alman, Benjamin A. Genot, Elisabeth Hinz, Boris 2014 Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation Journal of Cell Biology 207 2 283 297
The Journal of Cell Biology
Journal of Cell Biology, vol. 207, no. 2, pp. 283-297
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

A mild strain induced by matrix remodeling mechanically primes latent TGF-β1 for its subsequent activation and release in response to contractile forces.
Integrin-mediated force application induces a conformational change in latent TGF-β1 that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbe96936a8fa8552a8ef499e9c8b363
http://hdl.handle.net/10550/54633

alpha v beta 5/beta 6 integrin suppression leads to a stimulation of alpha 2 beta 1 dependent cell migration resistant to PI3K/Akt inhibition

Autor: Véronique Rigot, Céline Defilles, Jean-Claude Lissitzky, Estelle Delamarre, Naziha Marrakchi, Marie-Pierre Montero, Charles Prévôt, Frédéric André, José Luis

Publikováno v: Experimental Cell Research
Experimental Cell Research, Elsevier, 2009, 315 (11), pp.1840-1849. ⟨10.1016/j.yexcr.2009.03.014⟩

Crosstalk between integrins is involved in the regulation of various cell functions including cell migration. Here we identify the interplay between the integrins alpha v beta 5/beta 6 and alpha 2 beta 1 during cell migration toward type I collagen.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2f47b03b489761005cbd4506f893b8
https://hal-riip.archives-ouvertes.fr/pasteur-02049092

Integrins are involved in synaptogenesis, cell spreading, and adhesion in the postnatal brain

Autor: Dominique Muller, Marlis Moosmayer, Leslie Sargent Jones, Nicolas Toni, Irina Nikonenko, Yasushi Shigeri

Publikováno v: Developmental Brain Research, Vol. 140, No 2 (2003) pp. 185-194

Integrins are a major family of heterodimeric surface glycoproteins that act as adhesion molecules, have a spectrum of extracellular matrix (ECM) molecules as their ligands, and regulate a variety of cellular functions. Integrins are known to be crit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875f73d1a27e40ef7179f59f95bfa556
https://archive-ouverte.unige.ch/unige:10375

Small GTPases, adhesion, cell cycle control and proliferation

Autor: J M, Blanchard

Publikováno v: Pathologie Biologie
Pathologie Biologie, Elsevier Masson, 2000, 48 (3), pp.318--27

In many cells, proliferation is under the coordinated control of growth factors and the extracellular matrix (ECM). Autocriny and anchorage-independent growth are observed in many transformed cells where this balance is often altered. The outside-in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::32315314e3a3732fab251a55c1f26f9c
https://hal.archives-ouvertes.fr/hal-02196809