Zobrazeno 1 - 10
of 792
pro vyhledávání: '"Integrin β1"'
Autor:
Yan Han, Zehua Shao, Yuanhao Zhang, Huan Zhao, Zirui Sun, Chaokuan Yang, Hao Tang, Yu Han, Chuanyu Gao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study investigates how dynamic fluctuations in matrix stiffness affect the behavior of cardiac fibroblasts (CFs) within a three-dimensional (3D) hydrogel environment. Using hybrid hydrogels with tunable stiffness, we created an in vitro
Externí odkaz:
https://doaj.org/article/cfca4ea9b61a44578d109b58e84df563
Autor:
Meixuan Lin, Xiaoqiang Xu, Xiaoman Zhou, Hui Feng, Ruili Wang, Yunyun Yang, Jing Li, Ning Fan, Yazhuo Jiang, Xiang Li, Feng Guan, Zengqi Tan
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background Small extracellular vesicles (sEV) are closely associated with the development and metastasis of many types of mammalian cancer. Glycoconjugates are highly expressed on sEV and play important roles in sEV biogenesis and their inte
Externí odkaz:
https://doaj.org/article/185be2f490c64c67a6ab427562d9537c
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Integrins, which consist of two non-covalently linked α and β subunits, play a crucial role in cell–cell adhesion and cell-extracellular matrix (ECM) interactions. Among them, integrin β1 is the most common subunit and has emerged as a
Externí odkaz:
https://doaj.org/article/df26519eb68d4fbab26c426f528c9b6c
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27148- (2024)
Breast cancer (BC) remains a significant global health threat, with triple-negative breast cancer (TNBC) standing out as a particularly aggressive subtype lacking targeted therapies. Addressing this gap, we propose Quiescin Q6 sulfhydryl oxidase 2 (Q
Externí odkaz:
https://doaj.org/article/b657016ae0dd4fa0a79d2025ebc12038
Publikováno v:
Open Life Sciences, Vol 18, Iss 1, Pp 535-54 (2023)
Externí odkaz:
https://doaj.org/article/1db5dfc36e174b06a8c0527f70373257
Autor:
Xuan Li, Wanlu Xie, Qiong Pan, Xiaoxun Zhang, Liangjun Zhang, Nan Zhao, Qiaoling Xie, Jingjing Ding, Jin Chai
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Semaphorin7a (SEMA7A), a membrane-anchored member of the semaphorin protein family, could be involved in a diverse range of immune responses via its receptor integrin β1. Recently, we reported that the SEMA7A R148W mutation (a gain-of-funct
Externí odkaz:
https://doaj.org/article/486efb51c90c4370a4463954740905f9
Autor:
Yongqiu Cui, Siting Li, Weiyin Xu, Yeqiu Li, Jiali Xie, Dedong Wang, Jinshuo Guo, Jianwei Zhou, Xufei Feng, Lei Hou, Jue Liu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 829 (2024)
Avian metapneumovirus subgroup C (aMPV/C) causes respiratory diseases and egg dropping in chickens and turkeys, resulting in severe economic losses to the poultry industry worldwide. Integrin β1 (ITGB1), a transmembrane cell adhesion molecule, is pr
Externí odkaz:
https://doaj.org/article/057543281e554e8e9b4ceb8883109f83
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Abdominal aortic aneurysms have a high mortality rate. While surgery is the preferred treatment method, the biological repair of abdominal aortic aneurysms is being increasingly studied. We performed cellular and animal experiment
Externí odkaz:
https://doaj.org/article/091b96957ab64e57b3f03f2d8835c259
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Background Induced pluripotent stem cells (iPSCs) have the potential to promote wound healing; however, their adhesion to the extracellular matrix (ECM) might decrease iPSC migration, thereby limiting their therapeutic potential. Integrin β
Externí odkaz:
https://doaj.org/article/2606070f2e2e4b7babe6026d7267c25d
Autor:
Irina Langier Goncalves, Lama Awwad, Sharon Aviram, Talel Izraeli, Laris Achlaug, Ami Aronheim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17367 (2023)
Heart failure and cancer are currently the deadliest diseases in the Western world, posing the most pressing clinical challenges that remain unmet today. Both conditions share similar risk factors, including age, genetics, lifestyle, chronic inflamma
Externí odkaz:
https://doaj.org/article/307ace80bbbb471481539bed52933977