Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Integrative Aspects of Cell Biology"'
Autor:
Xiangwen Diao, Cuixia Zhan, Hongjian Ye, Haishan Wu, Chunyan Yi, Jianxiong Lin, Haiping Mao, Wei Chen, Xiao Yang
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111383- (2024)
Summary: The microenvironmental changes in peritoneal dialysis effluent (PDE) after long-term vintage (LV) of PD in patients with ultrafiltration failure (LV_UF) are unclear. Single-cell sequencing revealed that peritoneal neutrophils were elevated i
Externí odkaz:
https://doaj.org/article/d0cd8c04b843483bab8fd24f9cf8cf75
Autor:
Sun, Yuling 1, Yu, Huidi 1, Zhan, Zhihao 1, Liu, Wei 1, Liu, Penggang 1, Sun, Jing 1, Zhang, Pinghu 2, Wang, Xiaoquan 3, 4, Liu, Xiufan 3, 4, Xu, Xiulong 1, 4, 5, ∗
Publikováno v:
In iScience 17 January 2025 28(1)
Autor:
Darling M. Rojas-Canales, Soon Wei Wong, Elise J. Tucker, Anthony O. Fedele, Kym McNicholas, Anne-Sophie Mehdorn, Jonathan M. Gleadle
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110608- (2024)
Summary: Following kidney removal, the remaining kidney enlarges and increases its function. The mechanism and signals driving this compensatory kidney hypertrophy and the enlargement of its constituent kidney cells remains elusive. RNA-seq studies i
Externí odkaz:
https://doaj.org/article/361ec6fad4424aa18ff6c55b609c1008
Autor:
Diao, Xiangwen 1, 4, Zhan, Cuixia 2, 3, 4, Ye, Hongjian 2, 3, Wu, Haishan 2, 3, Yi, Chunyan 2, 3, Lin, Jianxiong 2, 3, Mao, Haiping 2, 3, Chen, Wei 2, 3, Yang, Xiao 2, 3, 5, ∗
Publikováno v:
In iScience 20 December 2024 27(12)
Autor:
Massenet, Jimmy 1, 2, Weiss-Gayet, Michèle 1, Bandukwala, Hina 2, Bouchereau, Wilhelm 1, Gobert, Stéphanie 1, Magnan, Mélanie 3, Hubas, Arnaud 4, Nusbaum, Patrick 4, Desguerre, Isabelle 5, 6, Gitiaux, Cyril 5, 7, Dilworth, F. Jeffrey 2, 8, 9, ∗, Chazaud, Bénédicte 1, 9, 10, ∗∗
Publikováno v:
In iScience 20 December 2024 27(12)
Autor:
Gil Sorek, Yulia Haim, Vered Chalifa-Caspi, Or Lazarescu, Maya Ziv-Agam, Tobias Hagemann, Pamela Arielle Nono Nankam, Matthias Blüher, Idit F. Liberty, Oleg Dukhno, Ivan Kukeev, Esti Yeger-Lotem, Assaf Rudich, Liron Levin
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110368- (2024)
Summary: Deconvolution algorithms mostly rely on single-cell RNA-sequencing (scRNA-seq) data applied onto bulk RNA-sequencing (bulk RNA-seq) to estimate tissues’ cell-type composition, with performance accuracy validated on deposited databases. Adi
Externí odkaz:
https://doaj.org/article/120ff37dd2ea4aedb2a1d37c407109f6
Autor:
Ludivine Renaud, Carole L. Wilson, Robert Lafyatis, Lynn M. Schnapp, Carol A. Feghali-Bostwick
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110010- (2024)
Summary: Systemic sclerosis (SSc) is a chronic disease characterized by fibrosis and vascular abnormalities in the skin and internal organs, including the lung. SSc-associated pulmonary fibrosis (SSc-PF) is the leading cause of death in SSc patients.
Externí odkaz:
https://doaj.org/article/3edca46345f34936801569b0ae6d94ae
Autor:
Karim Abu Nahia, Agata Sulej, Maciej Migdał, Natalia Ochocka, Richard Ho, Bożena Kamińska, Marcin Zagorski, Cecilia Lanny Winata
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110083- (2024)
Summary: We utilized scRNA-seq to delineate the diversity of cell types in the zebrafish heart. Transcriptome profiling of over 50,000 cells at 48 and 72 hpf defined at least 18 discrete cell lineages of the developing heart. Utilizing well-establish
Externí odkaz:
https://doaj.org/article/3b85eef0e98e44a28ec4ac33b87aa9b4
Autor:
Jiakun Miao, Kaiyi Zhang, Yu Yang, Shuang Xu, Juan Du, Tianwen Wu, Cong Tao, Yanfang Wang, Shulin Yang
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110015- (2024)
Summary: Cardiac damage is widely present in patients with metabolic diseases, but the exact pathophysiological mechanisms involved remain unclear. The porcine heart is an ideal material for cardiovascular research due to its similarities to the huma
Externí odkaz:
https://doaj.org/article/d31c97dfab674266bd4ba8a76336f02a
Autor:
Virginie Poindessous, Helene Lazareth, Gilles Crambert, Lydie Cheval, Julio L. Sampaio, Nicolas Pallet
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109737- (2024)
Summary: Long-chain acyl-CoA synthetase family 4 (ACSL4) metabolizes long-chain polyunsaturated fatty acids (PUFAs), enriching cell membranes with phospholipids susceptible to peroxidation and drive ferroptosis. The role of ACSL4 and ferroptosis upon
Externí odkaz:
https://doaj.org/article/3f539339bf8b48a5aa876261ccf4e0f6