Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Inta, Gribonika"'
1
Akademický článek
Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2
Autor: Kyong-Su Park, Kristina Svennerholm, Rossella Crescitelli, Cecilia Lässer, Inta Gribonika, Mickael Andersson, Jonas Boström, Hanna Alalam, Ali M Harandi, Anne Farewell, Jan Lötvall
Publikováno v: Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract The development of vaccines based on outer membrane vesicles (OMV) that naturally bud off from bacteria is an evolving field in infectious diseases. However, the inherent inflammatory nature of OMV limits their use as human vaccines. This st
Externí odkaz: https://doaj.org/article/fc6d21260c7847608c5befc299eb1627
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2
Akademický článek
Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy
Autor: Kyong‐Su Park, Kristina Svennerholm, Rossella Crescitelli, Cecilia Lässer, Inta Gribonika, Jan Lötvall
Publikováno v: Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer vaccine platform for efficiently provoking immune responses. However, OMV induce severe toxicity by activating the innate immune system. In this study, w
Externí odkaz: https://doaj.org/article/ab1e478af38d4cefaf70b2311e4622e6
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3
Akademický článek
Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10
Autor: Kyong-Su Park, Kristina Svennerholm, Ganesh V. Shelke, Elga Bandeira, Cecilia Lässer, Su Chul Jang, Rakesh Chandode, Inta Gribonika, Jan Lötvall
Publikováno v: Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Sepsis remains a source of high mortality in hospitalized patients despite proper antibiotic approaches. Encouragingly, mesenchymal stromal cells (MSCs) and their produced extracellular vesicles (EVs) have been shown to elicit ant
Externí odkaz: https://doaj.org/article/6747215d95154ee0b9c78cc9dd4e91c2
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5
Akademický článek
Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization
Autor: Yoshita Bhide, Wei Dong, Inta Gribonika, Daniëlle Voshart, Tjarko Meijerhof, Jacqueline de Vries-Idema, Stephen Norley, Kate Guilfoyle, Sarah Skeldon, Othmar G. Engelhardt, Louis Boon, Dennis Christensen, Nils Lycke, Anke Huckriede
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Adjuvanted whole inactivated virus (WIV) influenza vaccines show promise as broadly protective influenza vaccine candidates. Using WIV as basis we assessed the relative efficacy of different adjuvants by carrying out a head-to-head comparison of the
Externí odkaz: https://doaj.org/article/87556b2c48d6402581080a16c5962737
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6
Peyer’s patch TH17 cells are dispensable for gut IgA responses to oral immunization
Autor: Inta Gribonika, Anneli Strömberg, Cristina Lebrero-Fernandez, Karin Schön, James Moon, Mats Bemark, Nils Lycke
Publikováno v: Science Immunology. 7
T helper 17 (TH17) cells located at the Peyer’s patch (PP) inductive site and at the lamina propria effector site of the intestinal immune system are responsive to both pathogenic and commensal bacteria. Their plasticity to convert into follicular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e7354e8426d01d9ba8e47bc9b1b43f3
https://doi.org/10.1126/sciimmunol.abc5500
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8
The CTA1-DD adjuvant strongly potentiates follicular dendritic cell function and germinal center formation, which results in improved neonatal immunization
Autor: Johan Mattsson, Valentina Bernasconi, Karin Schön, Anneli Strömberg, Nils Lycke, Sophie Schussek, Inta Gribonika, Ulf Alexander Wenzel
Publikováno v: Mucosal Immunology
Vaccination of neonates and young infants is hampered by the relative immaturity of their immune systems and the lack of safe and efficacious vaccine adjuvants. Immaturity of the follicular dendritic cells (FDCs), in particular, appears to play a cri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22ac4ba1bf9179b055f526d18a686d9
http://europepmc.org/articles/PMC7223721
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10
Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy
Autor: Inta Gribonika, Cecilia Lässer, Rossella Crescitelli, Kristina Svennerholm, Kyong-Su Park, Jan Lötvall
Publikováno v: Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer vaccine platform for efficiently provoking immune responses. However, OMV induce severe toxicity by activating the innate immune system. In this study, we applied
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbc8fec2a5df066654de2a017a7de95
https://doi.org/10.1002/jev2.12120
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