Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Insung Park"'
Autor:
Insung Park, Rikako Yoshitake, Kazuki Kioka, Asuka Ishihara, Katsuhiko Yajima, Fusae Kawana, Toshio Kokubo, Ichiyo Matsuzaki, Takashi Kanbayashi, Masashi Yanagisawa, Kumpei Tokuyama
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110212- (2024)
Summary: Suvorexant is an orexin receptor antagonist that targets the wake-promoting system. Orexin is also known to regulate energy metabolism in rodents, but its role in humans remains largely unknown. Here, we assessed the effect of suvorexant (20
Externí odkaz:
https://doaj.org/article/92f0cbe36d0e4ea69e5029c525444da1
Autor:
Insung Park, Sergio Navarro-Serna, Raquel M. Pinho, Trish Berger, Elizabeth A. Maga, Joaqu?n Gadea, Seung K. Kim, Pablo J. Ross
Publikováno v:
Re:GEN Open, Vol 4, Iss 1, Pp 9-20 (2024)
Introduction: CRISPR/Cas9-mediated editing of embryos through microinjection is limited in efficiency because of high rates of mosaicism and off-target mutations. Electroporation has been proposed as an easier and faster procedure compared to single
Externí odkaz:
https://doaj.org/article/ca79aef459f941d493f6c8f1535e9b85
Autor:
Kwangmo Yang, Doyoun Kwon, Sungho Nam, Joonghyuk Kim, Yeon Sook Chung, Hyunjoon Yoo, Insung Park, Yongsup Park, Ji Whan Kim, Jaesang Lee
Publikováno v:
Physical Review X, Vol 14, Iss 4, p 041009 (2024)
In organic light-emitting diodes (OLEDs), understanding the efficiency loss mechanism known as exciton-polaron quenching (EPQ) has been a longstanding challenge. Traditionally, EPQ was believed to occur mainly within the bulk of the OLED emission lay
Externí odkaz:
https://doaj.org/article/c16d3c3acc3242a8ae798fac9d7fffa1
Autor:
Kelly Zacanti, Insung Park, Bret R. McNabb, Tara Marie Urbano, Elizabeth A. Maga, Barbara Jean Nitta-Oda, Joan D. Rowe, Sadie L. Hennig, Pablo Ross, Trish Berger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract A single locus on the X chromosome codes for androgen receptor (AR) although this gene is subject to alternative splicing. AR is expressed in multiple tissues in males and females and is essential for reproductive success in the male. Since
Externí odkaz:
https://doaj.org/article/99e8932e38ca4d709cd20264f74da735
Autor:
Jaehoon Seol, Chihiro Kokudo, Insung Park, Simeng Zhang, Katsuhiko Yajima, Tomohiro Okura, Kumpei Tokuyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Core body temperature (CBT) shows a diurnal rhythm, and the nocturnal decrease in CBT is blunted in older people. The physiological mechanisms responsible for the blunted nocturnal decrease in CBT in older people remain to be revealed. The a
Externí odkaz:
https://doaj.org/article/1a73fac7149d4086907ffd656e4e0735
Autor:
Sachiko Ito Uemura, Aya Imanishi, Yoshino Terui, Insung Park, Masahiro Satake, GoEun Han, Takanobu Shioya, Takashi Kanbayashi, Seiji Nishino
Publikováno v:
Neuropsychopharmacology Reports, Vol 42, Iss 3, Pp 288-298 (2022)
Abstract Introduction Current hypnotic agents have next‐day residual effects. The new orexin antagonist, suvorexant, has little muscle relaxation effect on the physical and cognitive function in the following morning and daytime. In this study, the
Externí odkaz:
https://doaj.org/article/44597579792f4a008dc723cf159308c2
Autor:
Jaehoon Seol, Jaehee Lee, Insung Park, Kumpei Tokuyama, Shoji Fukusumi, Toshio Kokubo, Masashi Yanagisawa, Tomohiro Okura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Although recent studies have examined the bidirectional associations between physical activity and sleep parameters, few have focused on older adults utilizing objective assessments, such as polysomnography. This micro-longitudinal observati
Externí odkaz:
https://doaj.org/article/4b86f2457e314ee2abbb95df41710f7c
Autor:
Insung Park, Chihiro Kokudo, Jaehoon Seol, Asuka Ishihara, Simeng Zhang, Akiko Uchizawa, Haruka Osumi, Ryusuke Miyamoto, Kazumasa Horie, Chihiro Suzuki, Yoko Suzuki, Tomohiro Okura, Javier Diaz, Kaspar E. Vogt, Kumpei Tokuyama
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Study objectiveTraditionally, age-related deterioration of sleep architecture in older individuals has been evaluated by visual scoring of polysomnographic (PSG) recordings with regard to total sleep time and latencies. In the present study, we addit
Externí odkaz:
https://doaj.org/article/cea919331442458f8862c68e54a1d66e
Autor:
Simeng Zhang, Yoshiaki Tanaka, Asuka Ishihara, Akiko Uchizawa, Insung Park, Kaito Iwayama, Hitomi Ogata, Katsuhiko Yajima, Naomi Omi, Makoto Satoh, Masashi Yanagisawa, Hiroyuki Sagayama, Kumpei Tokuyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Known as metabolic flexibility, oxidized substrate is selected in response to changes in the nutritional state. Sleep imposes an extended duration of fasting, and oxidized substrates during sleep were assumed to progressively shift from carb
Externí odkaz:
https://doaj.org/article/555456dd18f44553b8daa3a00c51eff0
Autor:
Insung Park, Chihiro Suzuki, Yoko Suzuki, Fusae Kawana, Katsuhiko Yajima, Shoji Fukusumi, Toshio Kokubo, Kumpei Tokuyama, Masashi Yanagisawa, Makoto Satoh
Publikováno v:
Sleep Medicine Research, Vol 12, Iss 1, Pp 57-63 (2021)
Background and Objective Patients with position-dependent obstructive sleep apnea have a > 2-fold higher apnea-hypopnea index when sleeping in a supine position compared with a non-supine position. We investigated the effect of body pillow use on sle
Externí odkaz:
https://doaj.org/article/a619d252fe8a4392b9a35018c791bbe4