Signalling pathways regulating muscle mass in ageing skeletal muscle

Autor: Luana Toniolo, L. Barberi, Astrid Y. Bijlsma, Antonio L. Serrano, Carel G. M. Meskers, Lars Larsson, Mario Pende, Rosario Rizzuto, Marco Sandri, Kenneth A. Dyar, Cristina Mammucari, Andrea B. Maier, Giorgia Pallafacchina, M. Roceri, Pura Muñoz-Cánoves, Stefano Schiaffino, Antonio Paoli, D. Pion, Giulia Milan, Bert Blaauw, Antonio Musarò, Carlo Reggiani, Vanina Romanello

Publikováno v: Biogerontology, 14(3), 303-23. Springer Netherlands
Biogerontology
Biogerontology, Springer Verlag, 2013, 14 (3), pp.303-23. ⟨10.1007/s10522-013-9432-9⟩
Biogerontology; Vol 14
Sandri, M, Barberi, L, Bijlsma, A Y, Blaauw, B, Dyar, K A, Milan, G, Mammucari, C, Meskers, C G M, Pallafacchina, G, Paoli, A, Pion, D, Roceri, M, Romanello, V, Serrano, A L, Toniolo, L, Larsson, L, Maier, A B, Munoz-Canoves, P, Musaro, A, Pende, M, Reggiani, C, Rizzuto, R & Schiaffino, S 2013, ' Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway ', Biogerontology, vol. 14, no. 3, pp. 303-323 . https://doi.org/10.1007/s10522-013-9432-9
Biogerontology, 2013, 14 (3), pp.303-23. ⟨10.1007/s10522-013-9432-9⟩
Biogerontology, 14(3), 303-323. Springer Netherlands
Biogerontology, 14(3), 303-323
Sandri, M, Barberi, L, Bijlsma, A Y, Blaauw, B, Dyar, K A, Milan, G, Mammucari, C, Meskers, C G M, Pallafacchina, G, Paoli, A, Pion, D, Roceri, M, Romanello, V, Serrano, A L, Toniolo, L, Larsson, L, Maier, A B, Muñoz-Cánoves, P, Musarò, A, Pende, M, Reggiani, C, Rizzuto, R & Schiaffino, S 2013, ' Signalling pathways regulating muscle mass in ageing skeletal muscle : the role of the IGF1-Akt-mTOR-FoxO pathway ', Biogerontology, vol. 14, no. 3, pp. 303-23 . https://doi.org/10.1007/s10522-013-9432-9

International audience; During ageing skeletal muscles undergo a process of structural and functional remodelling that leads to sarcopenia, a syndrome characterized by loss of muscle mass and force and a major cause of physical frailty. To determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f4a5d65f36ee74ba4de2ecd531c858
https://hdl.handle.net/1871.1/c3edf814-3c90-4667-8713-c3a120aff07a

Growth factors improve muscle healing in vivo

Autor: Menetrey, Jacques, Kasemkijwattana, C, Day, C S, Bosch, P, Vogt, M, Fu, F H, Moreland, M S, Huard, J

Publikováno v: Journal of Bone and Joint Surgery. British Volume, Vol. 82, No 1 (2000) pp. 131-7

Injury to muscles is very common. We have previously observed that basic fibroblast growth factor (b-FGF), insulin growth factor type 1 (IGF-1) and nerve growth factor (NGF) are potent stimulators of the proliferation and fusion of myoblasts in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba686ac7213097bf0a456abedd808e5c
https://doi.org/10.1302/0301-620x.82b1.0820131

Phosphatidylinositol 3-kinase-binding protein, PI3KAP/XB130, is required for cAMP-induced amplification of IGF mitogenic activity in FRTL-5 thyroid cells

Autor: Yamanaka, D., Akama, T., Fukushima, Toshiaki, Nedachi, T., Kawasaki, C., Chida, K., Minami, S., Suzuki, K., Hakuno, F., Takahashi, S.

We previously demonstrated that long-term pretreatment of rat FRTL-5 thyroid cells with TSH or cAMP-generating reagents potentiated IGF-I-dependent DNA synthesis. Under these conditions, cAMP treatment increased tyrosine phosphorylation of a 125-kDa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ee0fce62510ac6dfe1fb645d951da5
https://europepmc.org/articles/PMC5416991/

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury

Autor: C.M. Rodriguez-Ortigosa, Pauline K. Lund, S Sanz, James A. Fagin, Jolanta B. Pucilowska, James G. Simmons, María L. Martínez-Chantar, David A. Brenner, C.R. Fuller, Jesús Prieto, Pardo A, Liu S

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

BACKGROUND/AIM: Hepatic stellate cells (HSCs) express alpha-smooth muscle actin (alphaSMA) and acquire a profibrogenic phenotype upon activation by noxious stimuli. Insulin-like growth I (IGF-I) has been shown to stimulate HSCs proliferation in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6bd2edba979fa1a9c2a5bbdcee2694
https://hdl.handle.net/10171/23281

Role of IGF-I in ovine fetal and placental growth and development / Fong Lok.

Autor: Lok, Fong

Bibliography: p. 190-234.
276 p. : ill. ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
Aims to directly test the hypothesis that restricting placental delive

Externí odkaz: http://hdl.handle.net/2440/19339