Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Insulin receptor complex"'
Autor:
Sana Ahmed
The study of cell surface receptors and their associated signaling pathways on the plasma membrane are vital in understanding cellular responses. The insulin receptor is a tyrosine kinase that is activated in response to insulin microbeads presented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a961a22a01f88e42dca40f78e6d007
https://doi.org/10.32920/ryerson.14653134
https://doi.org/10.32920/ryerson.14653134
Publikováno v:
Journal of Peptide Science. 25
The physical interaction of the human growth factor receptor-bound protein 14 (hGrb14) and the insulin receptor (IR) represses insulin signaling. With respect to the recruiting mechanism of hGrb14 to IR respond to insulin stimulus, our previous repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4de48016ac718885d6abb31f6d63a5
https://doi.org/10.1002/psc.3207
https://doi.org/10.1002/psc.3207
Autor:
Umah Rani Kuppusamy, Pak Kheong Tan, Vannajan Sanghiran Lee, Sri Devi Sukumaran, Bavani Arumugam
Publikováno v:
Computational Biology and Chemistry. 92:107501
Naturally occurring proteins are emerging as novel therapeutics in the protein-based biopharmaceutical industry for the treatment of diabetes and obesity. However, proteins are not suitable for oral delivery due to short half-life, reduced physical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d298bd336d518b15465a47f758f7c31
https://doi.org/10.1016/j.compbiolchem.2021.107501
https://doi.org/10.1016/j.compbiolchem.2021.107501
Publikováno v:
Current proteinpeptide science. 21(1)
Insulin internalization and processing of the Insulin Receptor Complex (IRC) inside the cell are important components of the intracellular Mechanism of Insulin Action (MIA). They define the continuation of intracellular signaling of IRC and allow uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876a6a8cfec9586a0af0b23b3b0af0aa
https://pubmed.ncbi.nlm.nih.gov/30907311
https://pubmed.ncbi.nlm.nih.gov/30907311
Autor:
Yong Zi Tan, Hui Wei, Clinton S. Potter, Alex J. Noble, Zhening Zhang, Venkata P. Dandey, Bridget Carragher
Publikováno v:
Nature methods
Most protein particles prepared in vitreous ice for single-particle cryo-electron microscopy (cryo-EM) are adsorbed to air-water or substrate-water interfaces, which can cause the particles to adopt preferred orientations. By using a rapid plunge-fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3699e5847d9ce33503b50e404fbe80c4
https://pubmed.ncbi.nlm.nih.gov/30275590
https://pubmed.ncbi.nlm.nih.gov/30275590
Autor:
Nicholas B. Larson, Christina L. Wassel, Hugues Sicotte, Michael P. Bancks, Suzette J. Bielinski, Naomi Q. Hanson, James S. Pankow, Paul A. Decker
Background Hepatocyte growth factor (HGF) is a pleotropic factor posited to have metabolic homeostatic properties. The purpose of this study is to examine whether level of HGF is associated with the development of type 2 diabetes. Methods Data from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8b8eb149a1c7a935d5b63d828f46e
https://europepmc.org/articles/PMC4857763/
https://europepmc.org/articles/PMC4857763/
Autor:
Pierre De Meyts
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 37(4)
Progress in solving the structure of insulin bound to its receptor has been slow and stepwise, but a milestone has now been reached with a refined structure of a complex of insulin with a “microreceptor” that contains the primary binding site. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23575563387ec48408e36d3bb1ceedd1
https://pubmed.ncbi.nlm.nih.gov/25630923
https://pubmed.ncbi.nlm.nih.gov/25630923
Autor:
Wen-Hsing Lin, Lee-Ming Chuang, Chang Jen Huang, Min Wei Liu, Yann Jang Chen, Tong Yuan Tai, Hui Min Chang
Publikováno v:
Genomics. 74:12-20
SH3P12/CAP/ponsin, a gene product with a sorbin homology domain and three consecutive SH3 domains in the carboxy-terminus, has been isolated from murine adipocytes and identified as an important adaptor during insulin signaling. Here we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013c256a5bc7a7535654ccb3e5ddaf41
https://doi.org/10.1006/geno.2001.6541
https://doi.org/10.1006/geno.2001.6541
Publikováno v:
Journal of Cellular Biochemistry. 61:216-229
The influence of a mild heat shock on the fate of the insulin-receptor complex was studied in cultured fetal rat hepatocytes whose insulin glycogenic response is sensitive to heat [Zachayus and Plas (1995): J Cell Physiol 162:330-340]. After exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b5ea909240f7102b121ebc10752417
https://doi.org/10.1002/(sici)1097-4644(19960501)61:2<216::aid-jcb5>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19960501)61:2<216::aid-jcb5>3.0.co
Publikováno v:
Annals of the New York Academy of Sciences. 777:374-379
Glucose metabolism is essential for brain function and structure. Glucose contributes to the formation of neurotransmitters and is normally the only source for energy formation. There is increasing evidence that brain glucose metabolism is under cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ce9bcdf9536c05c246df84eb5067aa
https://doi.org/10.1111/j.1749-6632.1996.tb34448.x
https://doi.org/10.1111/j.1749-6632.1996.tb34448.x