Zobrazeno 1 - 10
of 396
pro vyhledávání: '"Insulin dysregulation"'
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 6, Pp 3309-3314 (2024)
Abstract Background Characterizing the lipid response to an oral glucose test (OGT) might improve our understanding of Equine Metabolic Syndrome. Hypothesis/Objectives To describe the effects of an OGT on lipid metabolism and determine the value of m
Externí odkaz:
https://doaj.org/article/58bb606c52ad4c8d979aef314256e0f9
Autor:
Kristen Thane, Johanna Sonntag, Tobias Warnken, Dania Reiche, Cassandra Uricchio, Nicholas Frank
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 6, Pp 3281-3287 (2024)
Abstract Background Testing for insulin dysregulation (ID) in horses is commonly performed to guide management and therapeutic strategies. Objectives To evaluate a newly developed glycemic pellets challenge (GPC) and compare results to those obtained
Externí odkaz:
https://doaj.org/article/b4bd6ceda6c94e6b82f918e0674b4459
Autor:
Caroline M. M. Loos, Shuang Zhao, Liang Li, Janet Li, Wei Han, Eric S. Vanzant, Kyle R. McLeod
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
The objective of this study was to investigate the effect of essential oil (EO) supplementation on insulin sensitivity (IS) and the plasma metabolome in insulin dysregulated (ID) horses. Horses were blocked by degree of IS and assigned randomly to tr
Externí odkaz:
https://doaj.org/article/a4d29ef30a884487b914220e59f9388f
Autor:
Kyle Fresa, Giovana D. Catandi, Luke Whitcomb, Raul A. Gonzalez-Castro, Adam J. Chicco, Elaine M. Carnevale
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Obesity is a complex disease associated with augmented risk of metabolic disorder development and cellular dysfunction in various species. The goal of the present study was to investigate the impacts of obesity on the metabolic health of old
Externí odkaz:
https://doaj.org/article/af5a638c740a46cd870e955799a53630
Autor:
Erin F. Pinnell, Laura D. Hostnik, Mauria R. Watts, Kathryn J. Timko, Allison A. Thriffiley, Mercedes R. Stover, Lauren E. Koenig, Olivia M. Gorman, Ramiro E. Toribio, Teresa A. Burns
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 1, Pp 102-110 (2024)
Abstract Background 5′‐adenosine monophosphate‐activated protein kinase (AMPK) agonists, particularly resveratrol (RES), have not been extensively evaluated for their effect on insulin dysregulation (ID) in horses. Objectives Evaluate the effec
Externí odkaz:
https://doaj.org/article/5c21a96aba6e4f97bffe7a6c2a4cd7e7
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2520-2528 (2023)
Abstract Background Decreasing hyperinsulinemia is crucial in preventing laminitis in insulin dysregulated (ID) horses. Complementary pharmacological treatments that efficiently decrease postprandial hyperinsulinemia in ID horses are needed. Objectiv
Externí odkaz:
https://doaj.org/article/ec181aa4d11c44c8b3a7c22177c862e5
Autor:
Olumide Odunayo Akinniyi, Anthony Kojo Beku Sackey, Gabriel Enenche Ochube, Philip Wayuta Mshelia
Publikováno v:
Ukrainian Journal of Veterinary and Agricultural Sciences, Vol 6, Iss 2, Pp 26-29 (2023)
Despite the growing concern about the impact of obesity on equine health, little information is available on equine obesity in Nigeria. The study aimed to determine the prevalence of obesity in leisure and polo horses as well as associated risk facto
Externí odkaz:
https://doaj.org/article/cfe25f00e60b4affa493ed8fe4135264
Publikováno v:
Acta Veterinaria Scandinavica, Vol 65, Iss 1, Pp 1-10 (2023)
Abstract Background Laminitis is a systemic condition resulting in debilitating pain and structural changes within the feet, and hence has major welfare implications. Causes include endocrine and systemic inflammatory conditions. Ponies are frequentl
Externí odkaz:
https://doaj.org/article/dd306979379649c8a59ee78aed43354f
Autor:
Brianna L. Clark, Nicholas J. Bamford, Allison J. Stewart, Molly E. McCue, Aaron Rendahl, Simon R. Bailey, François‐René Bertin, Elaine M. Norton
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 3, Pp 1186-1192 (2023)
Abstract Background The HMGA2:c.83G>A variant was identified in Welsh ponies having pleiotropic effects on height and insulin concentration. Objective Determine whether the HMGA2:c.83G>A variant is associated with decreased height and higher basal in
Externí odkaz:
https://doaj.org/article/599314bf860f4ca4a0e214637be611c1
Autor:
Demia J. deTonnerre, Carlos E. Medina Torres, Darko Stefanovski, Mary A. Robinson, Kate L. Kemp, François‐René Bertin, Andrew W. vanEps
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 2, Pp 703-712 (2023)
Abstract Background Sirolimus, a mechanistic target of rapamycin inhibitor, suppresses insulin production in other species and has therapeutic potential for hyperinsulinemia in horses. Hypothesis/Objective Determine the pharmacokinetics (PKs) of siro
Externí odkaz:
https://doaj.org/article/b482c3431f4944e5993feffca2498250