Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Insuk Lee"'
Autor:
Daniel Chang, Vinod K. Gupta, Benjamin Hur, Sergio Cobo-López, Kevin Y. Cunningham, Nam Soo Han, Insuk Lee, Vanessa L. Kronzer, Levi M. Teigen, Lioudmila V. Karnatovskaia, Erin E. Longbrake, John M. Davis, Heidi Nelson, Jaeyun Sung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Recent advancements in translational gut microbiome research have revealed its crucial role in shaping predictive healthcare applications. Herein, we introduce the Gut Microbiome Wellness Index 2 (GMWI2), an enhanced version of our original
Externí odkaz:
https://doaj.org/article/c365f9678a1e44e6af7e60c3b2af0a02
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 7, Pp 1501-1512 (2024)
Abstract Recent substantial evidence implicating commensal bacteria in human diseases has given rise to a new domain in biomedical research: microbiome medicine. This emerging field aims to understand and leverage the human microbiota and derivative
Externí odkaz:
https://doaj.org/article/0899f8650bfd4b69861dbeeedfddad52
Autor:
Nayeon Kim, Chan Yeong Kim, Junyeong Ma, Sunmo Yang, Dong Jin Park, Sang-Jun Ha, Peter Belenky, Insuk Lee
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Mouse gut microbiome research is pivotal for understanding the human gut microbiome, providing insights into disease modeling, host-microbe interactions, and the dietary influence on the gut microbiome. To enhance the translational value of mouse gut
Externí odkaz:
https://doaj.org/article/8835d8a79ab141e9940b5fbb2300b564
Autor:
Sungho Lee, Insuk Lee
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The gut microbiome, linked significantly to host diseases, offers potential for disease diagnosis through machine learning (ML) pipelines. These pipelines, crucial in modeling diseases using high-dimensional microbiome data, involve selecting profile
Externí odkaz:
https://doaj.org/article/eaf044b4aeab455bafc8101c655ad768
Autor:
Hye Ryun Kim, Da Hee Kim, Jung Eun Lee, Chang Gon Kim, Gamin Kim, Seyeon Park, Sang-Jun Ha, Jae-Won Cho, Martin Hemberg, Junha Cha, Euijeong Sung, Seungbyn Baek, Min Hee Hong, Nam Suk Sim, Hyun Jun Hong, Sun Ock Yoon, Yoon Woo Koh, Insuk Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background Oropharyngeal squamous cell carcinoma (OPSCC) induced by human papillomavirus (HPV-positive) is associated with better clinical outcomes than HPV-negative OPSCC. However, the clinical benefits of immunotherapy in patients with HPV-positive
Externí odkaz:
https://doaj.org/article/41f10413d0f440bdbb6c94e5f872b2a8
Autor:
Wei E. Gordon, Seungbyn Baek, Hai P. Nguyen, Yien-Ming Kuo, Rachael Bradley, Sarah L. Fong, Nayeon Kim, Alex Galazyuk, Insuk Lee, Melissa R. Ingala, Nancy B. Simmons, Tony Schountz, Lisa Noelle Cooper, Ilias Georgakopoulos-Soares, Martin Hemberg, Nadav Ahituv
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Frugivory evolved multiple times in mammals, including bats. However, the cellular and molecular components driving it remain largely unknown. Here, we use integrative single-cell sequencing (scRNA-seq and scATAC-seq) on insectivorous (Eptes
Externí odkaz:
https://doaj.org/article/63321723d9924faaa1c76d697644b935
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2296-2304 (2023)
Single-cell transcriptome data provide a unique opportunity to explore the gene networks of a particular cell type. However, insufficient capture rate and high dimensionality of single-cell RNA sequencing (scRNA-seq) data challenge cell-type-specific
Externí odkaz:
https://doaj.org/article/70a9808aa15b4a69b107f1b8c780b555
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, the authors construct 102 complete metagenome-assembled genomes (cMAGs) from Pacific Biosciences (PacBio) high-accuracy long-read (HiFi) metagenomic sequencing, showing as high nucleotide accuracy as reference genomes and revealing that regions
Externí odkaz:
https://doaj.org/article/441273d4d6144c03bf2b2762847d6a1c
Autor:
Taeyun A. Lee, Heonjong Han, Ahsan Polash, Seok Keun Cho, Ji Won Lee, Eun A. Ra, Eunhye Lee, Areum Park, Sujin Kang, Junhee L. Choi, Ji Hyun Kim, Ji Eun Lee, Kyung-Won Min, Seong Wook Yang, Markus Hafner, Insuk Lee, Je-Hyun Yoon, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The nucleolus is the traditional site for ribosomal RNA biogenesis. Here, the authors find that the nucleolus is a site of inflammatory pre-mRNA turnover and elucidated how immune homeostasis can be maintained by controlling inflammatory gene express
Externí odkaz:
https://doaj.org/article/3900adf1879d4f5d8d92fd2ebe8a5501
Autor:
Wei E. Gordon, Seungbyn Baek, Hai P. Nguyen, Yien-Ming Kuo, Rachael Bradley, Sarah L. Fong, Nayeon Kim, Alex Galazyuk, Insuk Lee, Melissa R. Ingala, Nancy B. Simmons, Tony Schountz, Lisa Noelle Cooper, Ilias Georgakopoulos-Soares, Martin Hemberg, Nadav Ahituv
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/fa5fd596502744f4b74fcbd8083c8533