Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Insook Jang"'
Autor:
Zhouji Chen, Shiyu Wang, Anita Pottekat, Alec Duffey, Insook Jang, Benny H. Chang, Jaehyung Cho, Brian N. Finck, Nicholas O. Davidson, Randal J. Kaufman
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101874- (2024)
Objectives: The assembly and secretion of hepatic very low-density lipoprotein (VLDL) plays pivotal roles in hepatic and plasma lipid homeostasis. Protein disulfide isomerase A1 (PDIA1/P4HB) is a molecular chaperone whose functions are essential for
Externí odkaz:
https://doaj.org/article/2eb00029f7a54fa383e62a065aa4cf9b
Autor:
Insook Jang, Anita Pottekat, Juthakorn Poothong, Jing Yong, Jacqueline Lagunas-Acosta, Adriana Charbono, Zhouji Chen, Donalyn L Scheuner, Ming Liu, Pamela Itkin-Ansari, Peter Arvan, Randal J Kaufman
Publikováno v:
eLife, Vol 8 (2019)
Regulated proinsulin biosynthesis, disulfide bond formation and ER redox homeostasis are essential to prevent Type two diabetes. In ß cells, protein disulfide isomerase A1 (PDIA1/P4HB), the most abundant ER oxidoreductase of over 17 members, can int
Externí odkaz:
https://doaj.org/article/606748e9851d4069a19e7e64c04c8f22
Autor:
Eun A. Ra, Taeyun A. Lee, Seung Won Kim, Areum Park, Hyun jin Choi, Insook Jang, Sujin Kang, Jae Hee Cheon, Jin Won Cho, Ji Eun Lee, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
While non-canonical, Atg5/Atg7-independent autophagy has been reported to occur, molecular details of alternative autophagy pathways remain unknown. Here, the authors report that the protein TRIM31 mediates alternative autophagy in intestinal cells,
Externí odkaz:
https://doaj.org/article/105465ca7a7148d1ab2b63fadbbbcb8b
Publikováno v:
Nursing Forum. 57:9-17
BACKGROUND Providing a person-centered care (PCC) education program to nursing students is necessary. This study aims to determine the impact of a design-thinking based education program on how nursing students perceive PCC. METHODS Five 2-h lessons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9058600f4e96a59281c7dff3e94fa245
https://doi.org/10.1111/nuf.12641
https://doi.org/10.1111/nuf.12641
Autor:
Seung-Hyun Ro, Xiang Xue, Sadeesh K Ramakrishnan, Chun-Seok Cho, Sim Namkoong, Insook Jang, Ian A Semple, Allison Ho, Hwan-Woo Park, Yatrik M Shah, Jun Hee Lee
Publikováno v:
eLife, Vol 5 (2016)
The mTOR complex 1 (mTORC1) and endoplasmic reticulum (ER) stress pathways are critical regulators of intestinal inflammation and colon cancer growth. Sestrins are stress-inducible proteins, which suppress both mTORC1 and ER stress; however, the role
Externí odkaz:
https://doaj.org/article/a1a04df440cf407aa51e8d0b621b689e
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de6c3d7f8fc75ee5266756bd396aea16
https://doi.org/10.2139/ssrn.4201392
https://doi.org/10.2139/ssrn.4201392
Autor:
Shuling Guo, Cynthia Lebeaupin, Hong Sun, Jonamani Nayak, Thazha P. Prakash, Sue Murray, Leslie S. Satin, Vishal S. Parekh, Insook Jang, Jiangwei Zhang, Shannon M. Reilly, Zhouji Chen, Alan R. Saltiel, Julio E. Ayala, Jing Yong, Randal J. Kaufman
Publikováno v:
Science translational medicine, vol 13, iss 604
Sci Transl Med
Sci Transl Med
Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia, hyperinsulinemia, and insulin resistance (IR). During the early phase of T2D, insulin synthesis and secretion by pancreatic β cells is enhanced, which can lead to proinsul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddca7944502655eb70d7c96f1c46cdf6
https://escholarship.org/uc/item/0tt8b9v1
https://escholarship.org/uc/item/0tt8b9v1
Publikováno v:
Nurse education in practice. 56
Objective To evaluate an onsite patient-centered care (PCC) training program for nurses using a digital patient-storytelling approach. Background PCC is a dominant model for improving the quality of care. Effective strategies for providing PCC traini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa84366419331713293a468ab2c377a
https://pubmed.ncbi.nlm.nih.gov/34537670
https://pubmed.ncbi.nlm.nih.gov/34537670
Publikováno v:
Cellular Biology of the Endoplasmic Reticulum ISBN: 9783030676957
Protein aggregation is now a common hallmark of numerous human diseases, most of which involve cytosolic aggregates including Aβ (AD) and ⍺-synuclein (PD) in Alzheimer's disease and Parkinson's disease. However, it is also evident that protein agg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::068dc1935f9d1bfa0d7c5b0a45962e96
https://doi.org/10.1007/978-3-030-67696-4_6
https://doi.org/10.1007/978-3-030-67696-4_6