Inflammatory Biomarkers and Clinical Judgment in the Emergency Diagnosis of Urgent Abdominal Pain

Autor: Breidthardt, Tobias, Brunner-Schaub, Nora, Balmelli, Catharina, Insenser, Juan Jose Sancho, Burri-Winkler, Katrin, Geigy, Nicolas, Mundorff, Lukas, Exadaktylos, Aristomenis, Scholz, Julia, Haaf, Philip, Hamel, Christian, Frey, Daniel, Delport, Karen, Peacock, W. Frank, Freese, Michael, DiSomma, Salvatore, Todd, John, Rentsch, Katharina, Bingisser, Roland, Mueller, Christian

BACKGROUND: The early diagnosis of urgent abdominal pain (UAP) is challenging. Most causes of UAP are associated with extensive inflammation. Therefore, we hypothesized that quantifying inflammation using interleukin-6 and/or procalcitonin would prov

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Inflammatory Biomarkers and Clinical Judgment in the Emergency Diagnosis of Urgent Abdominal Pain.

Autor: Breidthardt T; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland; tobias.breidthardt@usb.ch.; Department of Internal Medicine, University Hospital, Basel, and University of Basel, Switzerland., Brunner-Schaub N; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland., Balmelli C; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland., Insenser JJS; Hospital del Mar, Barcelona, Spain., Burri-Winkler K; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Hospital del Mar, Barcelona, Spain., Geigy N; Kantonsspital Baselland, Liestal, Switzerland., Mundorff L; Kantonsspital Baselland, Liestal, Switzerland., Exadaktylos A; Emergency Department, Inselspital, Berne, Switzerland., Scholz J; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland., Haaf P; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Cardiology, University Hospital, Basel, and University of Basel, Switzerland., Hamel C; Department of Visceral Surgery, University Hospital, Basel, and University of Basel, Switzerland.; Department of Visceral Surgery, Kliniken des Landkreises, Lörrach, Germany., Frey D; Department of Visceral Surgery, University Hospital, Basel, and University of Basel, Switzerland.; Department of Surgery, Spital Wetzikon, Wetzikon, Switzerland., Delport K; Emergency Department, Kantonspital Baselland, Bruderholz, Switzerland., Peacock WF; Department of Emergency Medicine, Baylor College of Medicine, Houston, TX., Freese M; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Cardiology, University Hospital, Basel, and University of Basel, Switzerland., DiSomma S; Emergency Department, San Andrea Hospital, University Sapienza, Rome, Italy., Todd J; Singulex Inc., Clinical Research, Alameda, CA., Rentsch K; Department of Laboratory Medicine, University Hospital, Basel, and University of Basel, Switzerland., Bingisser R; Emergency Department, University Hospital, Basel, and University of Basel, Switzerland., Mueller C; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Cardiology, University Hospital, Basel, and University of Basel, Switzerland., Walter J; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Cardiology, University Hospital, Basel, and University of Basel, Switzerland., Twerenbold R; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland.; Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany., Nestelberger T; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland., Boeddinghaus J; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland., Badertscher P; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland., du Fay de Lavallaz J; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland., Puelacher C; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland., Wildi K; Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.; Department of Medicine, University Hospital, Basel, and University of Basel, Switzerland.

Publikováno v: Clinical chemistry [Clin Chem] 2019 Feb; Vol. 65 (2), pp. 302-312. Date of Electronic Publication: 2018 Dec 05.