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The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model.

Autor: Inselman AL; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Masters EA; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Moore JN; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Agarwal R; Office of New Drug Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States., Gassman A; Division of Urology, Obstetrics and Gynecology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States., Kuijpers G; Division of Urology, Obstetrics and Gynecology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States., Beger RD; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Delclos KB; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Swift S; Office of Dietary Supplement Program, Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, MD, United States., Camacho L; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Vanlandingham MM; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Sloper D; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Nakamura N; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Gamboa da Costa G; Office of the Center Director, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Woodling K; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Bryant M; Office of Scientific Coordination, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Trbojevich R; Office of Scientific Coordination, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Wu Q; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., McLellen F; Office of Scientific Coordination, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States., Christner D; Office of New Drug Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Apr 16; Vol. 15, pp. 1365151. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).

Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone.

Autor: Nakamura N; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States. Electronic address: Noriko.Nakamura@fda.hhs.gov., Vijay V; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Desai VG; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Hansen DK; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Han T; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Chang CW; Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Chen YC; Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Harrouk W; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, United States., McIntyre B; National Toxicology Program, Research Triangle Park, NC 27709, United States., Foster PM; National Toxicology Program, Research Triangle Park, NC 27709, United States., Fuscoe JC; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States., Inselman AL; Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, United States.

Publikováno v: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2018 Dec; Vol. 82, pp. 111-123. Date of Electronic Publication: 2018 Oct 11.

Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity.

Autor: Chen X; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: xchen@cpsc.gov., Han T; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: Tao.Han@fda.hhs.gov., Fisher JE; Center for Drug Evaluation and Research, Food and Drug Administration, United States. Electronic address: Jedward.fisher@fda.hhs.gov., Harrouk W; Center for Drug Evaluation and Research, Food and Drug Administration, United States. Electronic address: Wafa.Harrouk@fda.hhs.gov., Tassinari MS; Center for Drug Evaluation and Research, Food and Drug Administration, United States. Electronic address: Melissa.Tassinari@fda.hhs.gov., Merry GE; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: Gwenn.Merry@fda.hhs.gov., Sloper D; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: Daniel.Sloper@fda.hhs.gov., Fuscoe JC; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: James.Fuscoe@fda.hhs.gov., Hansen DK; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: deborah_hansen@sbcglobal.net., Inselman AL; Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, United States. Electronic address: Amy.Inselman@fda.hhs.gov.

Publikováno v: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2017 Apr; Vol. 69, pp. 75-83. Date of Electronic Publication: 2017 Feb 08.