A missense mutation in human INSC causes peripheral neuropathy

Autor: Jui-Yu Yeh, Hua-Chuan Chao, Cheng-Li Hong, Yu-Chien Hung, Fei-Yang Tzou, Cheng-Tsung Hsiao, Jeng-Lin Li, Wen-Jie Chen, Cheng-Ta Chou, Yu-Shuen Tsai, Yi-Chu Liao, Yu-Chun Lin, Suewei Lin, Shu-Yi Huang, Marina Kennerson, Yi-Chung Lee, Chih-Chiang Chan

Publikováno v: EMBO Molecular Medicine, Vol 16, Iss 5, Pp 1091-1114 (2024)

Abstract PAR3/INSC/LGN form an evolutionarily conserved complex required for asymmetric cell division in the developing brain, but its post-developmental function and disease relevance in the peripheral nervous system (PNS) remains unknown. We mapped

Externí odkaz: https://doaj.org/article/5359f09eb23c4e93a0c5ca897d7a0804

Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC

Autor: Mimmi S. Ballard, Anna Zhu, Naomi Iwai, Michael Stensrud, Aurelia Mapps, Maira Pia Postiglione, Juergen A. Knoblich, Lindsay Hinck

Publikováno v: Cell Reports, Vol 13, Iss 2, Pp 290-301 (2015)

Tissue homeostasis requires somatic stem cell maintenance; however, mechanisms regulating this process during organogenesis are not well understood. Here, we identify asymmetrically renewing basal and luminal stem cells in the mammary end bud. We dem

Externí odkaz: https://doaj.org/article/602e16afa1524729ae72fe9240138cd9

A Kinase Duet Performance in the Asymmetric Division of Drosophila Neuroblasts

Autor: Christopher A. Johnston

Publikováno v: Journal of Developmental Biology, Vol 5, Iss 3, p 7 (2017)

The ability of progenitor stem cells to divide asymmetrically allows for the production of diverse daughter cell fates.[...]

Externí odkaz: https://doaj.org/article/87b3f79ee3bc46cf98207ed1c2eda53a

Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC

Autor: Michael Stensrud, Mimmi S. Ballard, Lindsay Hinck, Aurelia Mapps, Maria Pia Postiglione, Naomi Iwai, Anna Zhu, Juergen A. Knoblich

Publikováno v: Cell Reports, Vol 13, Iss 2, Pp 290-301 (2015)
Cell reports, vol 13, iss 2
Ballard, MS; Zhu, A; Iwai, N; Stensrud, M; Mapps, A; Postiglione, MP; et al.(2015). Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC. Cell Reports, 13(2), 290-301. doi: 10.1016/j.celrep.2015.09.006. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/5w0487px

© 2015 The Authors. Tissue homeostasis requires somatic stem cell maintenance; however, mechanisms regulating this process during organogenesis are not well understood. Here, we identify asymmetrically renewing basal and luminal stem cells in the ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3481608a6ab9e3a2511b45d4056f27
https://doi.org/10.1016/j.celrep.2015.09.006

Regulation of mammary stem cell self-renewal by the SLIT2/ROBO1 signaling axis

Autor: Ballard, Mimmi

Publikováno v: Ballard, Mimmi. (2015). Regulation of mammary stem cell self-renewal by the SLIT2/ROBO1 signaling axis. UC Santa Cruz: Molecular Cell and Developmental Biology. Retrieved from: http://www.escholarship.org/uc/item/86s7s6gd

The SLIT2/ROBO1 signaling axis regulates ductal development and stem cell self-renewal by controlling Inscuteable through the SNAIL transcription factorbyMIMMI SEWERIN BALLARDThe breast, or mammary gland in mice, is an epithelial bilayered ductal sys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::db8a1806b29e0cb50c0c95808e080d44
http://www.escholarship.org/uc/item/86s7s6gd