Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Insaf F, Khalil"'
Autor:
Emad Masuadi, Hayder A. Giha, Mustafa I. Elbashir, Insaf F. Khalil, Ib C. Bygbjerg, Michael Alifrangis, Ishraga E. A-Elbasit
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 27:725-732
Estimation of the prevalence of the molecular markers of sulfadoxine/pyrimethamine (SP) and chloroquine (CQ) resistance and validation of the association of mutations with resistance in different settings is needed for local policy guidance and for c
Evidence of Still-Ongoing Convergence Evolution of the Lactase Persistence T-13910 Alleles in Humans
Autor:
Michael J. Lentze, Erkki Savilahti, Luigi Greco, Kazima B. Bulayeva, Joseph D. Terwilliger, J.K. Seo, Soheila Rahgozar, Leena Peltonen, Aimee Trudeau, Timo Sahi, Nael Shaat, Galina Verschubskaya, Markus Perola, Salvatore Auricchio, Luigi Maiuri, Sirajedin S. Natah, Irma Järvelä, Insaf F. Khalil, Nabil Enattah, Michael Alifrangis, David Comas, Ville Pimenoff, Mauro Rossi, Andrew Kozlov, Antti Sajantila, Leif Groop, S. Qasim Mehdi
Publikováno v:
The American Journal of Human Genetics. 81:615-625
A single-nucleotide variant, C/T(-13910), located 14 kb upstream of the lactase gene (LCT), has been shown to be completely correlated with lactase persistence (LP) in northern Europeans. Here, we analyzed the background of the alleles carrying the c
Autor:
Anders Enevold, Anja T. R. Jensen, Michael Alifrangis, Trine Staalsoe, Thor G. Theander, David C. Warhurst, Martha M. Lemnge, Anita M. Rønn, Insaf F. Khalil, John Lusingu, Lasse S Vestergaard, Ib C. Bygbjerg, Michael B. Dalgaard
Publikováno v:
The Journal of Infectious Diseases. 193:1738-1741
Two main haplotypes, CVIET and SVMNT, of the Plasmodium falciparum chloroquine-resistance transporter gene (Pfcrt) are linked to 4-aminoquinoline resistance. The CVIET haplotype has been reported in most malaria-endemic regions, whereas the SVMNT hap
Autor:
D. S. Tarimo, Richardo Thompson, Sonja Enosse, Anita M. Rønn, Martha M. Lemnge, Insaf F. Khalil, Ib C. Bygbjerg, Michael Alifrangis
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 69:601-606
Plasmodium falciparum resistance to sulfadoxine/pyrimethamine (S/P) is due to mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhfr) genes. Large-scale screening of the prevalence of these mutations could facilitate the
Publikováno v:
Hydrobiologia. 259:195-201
Twenty water samples and 30 plankton samples were taken from the sewage disposal site (El Lamab, south of Khartoum), from 250 m upstream and 250 m downstream during January–March, 1987 and Februar–April, 1988. The water samples were examined for
Autor:
Ulla Abildrup, Nyagonde Nyagonde, Thor G. Theander, Martha M. Lemnge, Insaf F. Khalil, Ola Per-Eric Persson, Lotte Christine Groth Hoegberg, Deogratius Maiga, Ib C. Bygbjerg, Lasse S Vestergaard, Lene Alifrangis, Michael Alifrangis
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 54(1)
Artemether-lumefantrine (ARM-LUM) has in recent years become the first-line treatment for uncomplicated malaria in many Sub-Saharan African countries. Vigorous monitoring of the therapeutic efficacy of this treatment is needed. This requires high-qua
Autor:
Michael, Alifrangis, John P, Lusingu, Bruno, Mmbando, Michael B, Dalgaard, Lasse S, Vestergaard, Deus, Ishengoma, Insaf F, Khalil, Thor G, Theander, Martha M, Lemnge, Ib C, Bygbjerg
Publikováno v:
The American journal of tropical medicine and hygiene. 80(4)
In January 2007, Tanzania replaced sulfadoxine-pyrimethamine (SP) with artemether-lumefantrine for treatment of uncomplicated malaria. This study examined the impact of widespread SP use on molecular markers of Plasmodium falciparum drug resistance i
Autor:
Jeong Kee Seo, Insaf F. Khalil, Leif Groop, Hatem El-Shanti, Faiqa Imtiaz, Else Marie Vestergaard, Abdrazak Natah, Mikko Kuokkanen, Heli Rasinperä, Sirajedin S. Natah, David Comas, Brian F. Meyer, Mette Olaf Nielsen, S. Qasim Mehdi, Rikke Lewinski, Mohamed S. Rashed, Nabil Enattah, Tine G.K. Jensen, Michael Alifrangis, Jesper T. Troelsen, Leena Peltonen, Ahmed Ali
Publikováno v:
Enattah, NS, Jensen, TG, Nielsen, M, Lewinski, R, Kuokkanen, M, Rasinpera, H, El-Shanti, H, Seo, JK, Alifrangis, M, Khalil, IF, Natah, A, Ali, A, Natah, S, Comas, D, Mehdi, SQ, Groop, L, Vestergaard, E M, Imtiaz, F, Rashed, MS, Meyer, B, Troelsen, J & Peltonen, L 2008, ' Independent introduction of two lactase-persistence alleles into humanpopulations reflects different history of adaptation to milk culture ', American Journal of Human Genetics, vol. 82, no. 1, pp. 57-72 . https://doi.org/10.1016/j.ajhg.2007.09.012
Udgivelsesdato: jan The T(-13910) variant located in the enhancer element of the lactase (LCT) gene correlates perfectly with lactase persistence (LP) in Eurasian populations whereas the variant is almost nonexistent among Sub-Saharan African populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c3b03e1d3631a071aec67888c21290
https://pure.au.dk/portal/da/publications/independent-introduction-of-two-lactasepersistence-alleles-into-humanpopulations-reflects-different-history-of-adaptation-to-milk-culture(55a85440-c6b8-11dd-9710-000ea68e967b).html
https://pure.au.dk/portal/da/publications/independent-introduction-of-two-lactasepersistence-alleles-into-humanpopulations-reflects-different-history-of-adaptation-to-milk-culture(55a85440-c6b8-11dd-9710-000ea68e967b).html
Autor:
Michael Alifrangis, M. M. Kheir, E. M. Malik, Khalid A Elmardi, Insaf F. Khalil, Maha E. Osman, A. M. Ibrahium, I. Adam
Publikováno v:
Annals of tropical medicine and parasitology. 101(1)
Artemisinin-based combination therapy (ACT) is increasingly being adopted as the first-line treatment for malaria in sub-Saharan Africa. In September-November 2005, in New Halfa, eastern Sudan, the efficacy of artesunate-sulfadoxine-pyrimethamine (AS
Autor:
Michael Alifrangis, Ishraga E. A-Elbasit, Mustafa I. Elbashir, Hayder A. Giha, Insaf F. Khalil
Publikováno v:
Tropical medicineinternational health : TMIH. 11(5)
Summary Objective To compare the efficacy of sulfadoxine–pyremethamine (SP) + chloroquine (CQ) combination treatment against falciparum malaria with SP treatment alone. Method In-vivo study of 254 patients with uncomplicated Plasmodium falciparum m