Výsledky vyhledávání - "Inonge van Twillert"

Akademický článek

Reduced Bordetella pertussis-specific CD4+ T-Cell Responses at Older Age

Autor: Eleonora E. Lambert, Inonge van Twillert, Lisa Beckers, Martien C. M. Poelen, Wanda G. H. Han, Daan K. J. Pieren, Cécile A. C. M. van Els

Publikováno v: Frontiers in Aging, Vol 2 (2022)

Pertussis, a human-specific respiratory infectious disease caused by the Gram-negative bacterium Bordetella pertussis (Bp), remains endemic with epidemic years despite high vaccination coverage. Whereas pertussis vaccines and natural infection with B

Externí odkaz: https://doaj.org/article/29d076df90a9491bbeaf1174e8a1a951

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Akademický článek

The Use of Innovative Two-Component Cluster Analysis and Serodiagnostic Cut-Off Methods to Estimate Prevalence of Pertussis Reinfections.

Autor: Inonge van Twillert, Axel A Bonačić Marinović, Jacqueline A M van Gaans-van den Brink, Betsy Kuipers, Guy A M Berbers, Nicoline A T van der Maas, Theo J M Verheij, Florens G A Versteegh, Peter F M Teunis, Cécile A C M van Els

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148507 (2016)

Bordetella pertussis circulates even in highly vaccinated countries affecting all age groups. Insight into the scale of concealed reinfections is important as they may contribute to transmission. We therefore investigated whether current single-point

Externí odkaz: https://doaj.org/article/f3126c3715a14cb5bf4bdf1cd0f91b0d

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Akademický článek

Autor: Inonge van Twillert, Jacqueline A M van Gaans-van den Brink, Martien C M Poelen, Kina Helm, Betsy Kuipers, Maarten Schipper, Claire J P Boog, Theo J M Verheij, Florens G A Versteegh, Cécile A C M van Els

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85227 (2014)

For a better understanding of the maintenance of immune mechanisms to Bordetella pertussis (Bp) in relation to age, we investigated the dynamic range of specific B cell responses in various age-groups at different time points after a laboratory confi

Externí odkaz: https://doaj.org/article/4e6ffdc2fff54c18a5a85814b998abb6

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Akademický článek

Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age.

Autor: Wanda G H Han, Inonge van Twillert, Martien C M Poelen, Kina Helm, Jan van de Kassteele, Theo J M Verheij, Florens G A Versteegh, Claire J P Boog, Cécile A C M van Els

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e83583 (2013)

Pertussis is still occurring in highly vaccinated populations, affecting individuals of all ages. Long-lived Th1 CD4(+) T cells are essential for protective immunity against pertussis. For better understanding of the limited immunological memory to B

Externí odkaz: https://doaj.org/article/32a16447e8e54a848bbfd72431e7af2c

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Reduced

Autor: Eleonora E, Lambert, Inonge, van Twillert, Lisa, Beckers, Martien C M, Poelen, Wanda G H, Han, Daan K J, Pieren, Cécile A C M, van Els

Publikováno v: Frontiers in aging. 2

Pertussis, a human-specific respiratory infectious disease caused by the Gram-negative bacterium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3ac1fe0bb00c12d5132c99fe96c3443
https://pubmed.ncbi.nlm.nih.gov/35822011

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Impact of age and vaccination history on long-term serological responses after symptomatic B. pertussis infection, a high dimensional data analysis

Autor: Betsy Kuipers, Jacqueline A. M. van Gaans-van den Brink, Axel A. Bonačić Marinović, Elisabeth A. M. Sanders, Cécile A. C. M. van Els, Inonge van Twillert

Publikováno v: Scientific Reports, 7. Nature Publishing Group
Scientific Reports

Capturing the complexity and waning patterns of co-occurring immunoglobulin (Ig) responses after clinical B. pertussis infection may help understand how the human host gradually loses protection against whooping cough. We applied bi-exponential model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a01c2a2c24861bfcfe55662fdcb111d
https://dspace.library.uu.nl/handle/1874/348899

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Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age

Autor: Claire J. P. Boog, Jan van de Kassteele, Cécile A. C. M. van Els, Martien C. M. Poelen, Inonge van Twillert, Wanda G. H. Han, Florens G. A. Versteegh, Theo J M Verheij, Kina Helm

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e83583 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5630badfe11e2a980f8a1800ec45d84b
http://europepmc.org/articles/PMC3877060?pdf=render

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The Use of Innovative Two-Component Cluster Analysis and Serodiagnostic Cut-Off Methods to Estimate Prevalence of Pertussis Reinfections

Autor: Theo J M Verheij, Florens G. A. Versteegh, Cécile A. C. M. van Els, Peter Teunis, Inonge van Twillert, Nicoline A.T. van der Maas, Axel A. Bonačić Marinović, Jacqueline A. M. van Gaans-van den Brink, Guy A. M. Berbers, Betsy Kuipers

Publikováno v: PLoS ONE [E], 11(2). Public Library of Science
PLoS ONE, Vol 11, Iss 2, p e0148507 (2016)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bcd5e94d15523551738ecefd61e059
https://doi.org/10.1371/journal.pone.0148507

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Waning and aging of cellular immunity toB. pertussis

Autor: Cécile A. C. M. van Els, Wanda G. H. Han, Inonge van Twillert

Publikováno v: Pathogens and Disease. :ftv071

While it is clear that the maintenance of Bordetella pertussis-specific immunity evoked both after vaccination and infection is insufficient, it is unknown at which pace waning occurs and which threshold levels of sustained functional memory B and T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::374c7771e6731eccf2707d4496936297
https://doi.org/10.1093/femspd/ftv071

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