Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Inoka S. Balasooriya"'
Autor:
D. Shyamali Wimalasena, Bruce J. Heyen, Inoka S. Balasooriya, Kandatege Wimalasena, Rohan P. Perera
Publikováno v:
Journal of Medicinal Chemistry. 51:760-768
The active metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), N-methyl-4-phenylpyridinium (MPP(+)), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Inhibition of mitochondrial complex I a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d25ee3eae3a57b5a24ebfd796bd494
https://doi.org/10.1021/jm070875p
https://doi.org/10.1021/jm070875p
Publikováno v:
The FASEB Journal. 21
SH-SY5Y and MN9D cell lines are commonly used dopaminergic models in studies related to neurotoxicity, oxidative stress, and neurodegenerative diseases. Early studies suggested that SH-SY5Y cells do not convert intracellular DA to NE even though high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16dbfe12b69a888030ed848579916f6c
https://doi.org/10.1096/fasebj.21.6.a1274-a
https://doi.org/10.1096/fasebj.21.6.a1274-a
Autor:
D. Shyamali Wimalasena, Rohan P. Perera, Bruce J. Heyen, Inoka S. Balasooriya, Kandatege Wimalasena
Publikováno v:
Journal of Medicinal Chemistry; Jan2008, Vol. 51 Issue 4, p760-768, 9p