Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Inoculum effect"'
Autor:
Xueting Wang, Luying Xiong, Yuan Wang, Kai Yang, Tingting Xiao, Xiaohui Chi, Tao Chen, Yanzi Zhou, Ping Lu, Dilimulati Dilinuer, Pin Shen, Yunbo Chen, Yonghong Xiao
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Objective To evaluate effect of inoculum size of extended-spectrum β-Lactamase (ESBL)-producing-, AmpC-producing-, and KPC-producing Escherichia coli and Klebsiella pneumoniae on the in vitro antibacterial effects of imipenem/relebactam (IM
Externí odkaz:
https://doaj.org/article/b70cc2a4acd54df29e62453b3e590bbd
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Staphylococcus aureus can produce β-lactamases capable of hydrolyzing penicillins and first-generation cephalosporins. The propensity of type A and type C β-lactamase-producing S. aureus (TAPSA and TCPSA) to hydrolyze cefazolin at a high i
Externí odkaz:
https://doaj.org/article/4fb8d6c0b4f942c0a3178bd093fca085
Akademický článek
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Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Cefiderocol and aztreonam-avibactam (ATM-AVI) both had activity against carbapenem-resistant Gram-negative bacilli, including those that produce metallo-β-lactamases (MBLs). We compared the in vitro activities and inoculum effects of these
Externí odkaz:
https://doaj.org/article/f821c8d8f304489c9ca276111366d1c4
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Phenotypic drug susceptibility testing (DST) requires a standardized amount of inoculum to produce reproducible susceptibility results. The most critical step in the application of DST in Mycobacterium tuberculosis isolates is the preparatio
Externí odkaz:
https://doaj.org/article/4bbba05b6f1746cc89d609e05b181788
Autor:
Maria V. Golikova, Kamilla N. Alieva, Elena N. Strukova, Daria A. Kondratieva, Nika F. Petrova, Mayya A. Petrova, Stephen H. Zinner
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1717 (2023)
Resistance to carbapenems has become a problem due to Klebsiella pneumoniae (K. pneumoniae), harboring carbapenemases. Among them, there are isolates that are recognized as carbapenem-susceptible; however, these carbapenemase-producing strains with l
Externí odkaz:
https://doaj.org/article/7ed4756063d14284b59559bf78120cdf
Autor:
Elena N. Strukova, Maria V. Golikova, Svetlana A. Dovzhenko, Mikhail B. Kobrin, Stephen H. Zinner
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1705 (2023)
The emergence of bacteria resistant to beta-lactam/beta-lactamase inhibitor combinations is insufficiently studied, wherein the role of the inoculum effect (IE) in decreased efficacy is unclear. To address these issues, 5-day treatments with doripene
Externí odkaz:
https://doaj.org/article/0eb162d7b0624be4a67414649c819b3a
Autor:
Lukas Geyrhofer, Philip Ruelens, Andrew D. Farr, Diego Pesce, J. Arjan G. M. de Visser, Naama Brenner
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT A common strategy used by bacteria to resist antibiotics is enzymatic degradation or modification. This reduces the antibiotic threat in the environment and is therefore potentially a collective mechanism that also enhances the survival of n
Externí odkaz:
https://doaj.org/article/a86d073a0a444c1cb67ddc457d60eb0c
Akademický článek
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Autor:
Alwin Tilanus, George Drusano
Publikováno v:
Antibiotics, Vol 12, Iss 11, p 1581 (2023)
Certain classes of antibiotics show “concentration dependent” antimicrobial activity; higher concentrations result in increased bacterial killing rates, in contrast to “time dependent antibiotics”, which show antimicrobial activity that depen
Externí odkaz:
https://doaj.org/article/90c93b1efe374978af370636454ad2a0