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pro vyhledávání: '"Ino80 complex"'
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Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Actin is not only one of the most abundant proteins in eukaryotic cells, but also one of the most versatile. In addition to its familiar involvement in enabling contraction and establishing cellular motility and scaffolding in the cytosol, actin has
Externí odkaz:
https://doaj.org/article/773c6aa56cd4491a9abbe9ffdc5f07bf
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The generation of individual neurons (neurogenesis) during cortical development occurs in discrete steps that are subtly regulated and orchestrated to ensure normal histogenesis and function of the cortex. Notably, various gene expression programs ar
Externí odkaz:
https://doaj.org/article/27ad156008e240568bf88e076b00ff4c
Publikováno v:
Plant Cell
In the INO80 chromatin remodeling complex, all of the accessory subunits are assembled on the following three domains of INO80: N-terminal domain (NTD), HSA domain, and ATPase domain. Although the ATPase and HSA domains and their interacting accessor
Publikováno v:
Journal of Molecular Cell Biology
The presence and functions of nuclear actin have been controversial due to the lack of molecular mechanisms. Nuclear actin and actin-related proteins (Arps) are subunits of several chromatin remodelers, including the evolutionarily conserved INO80 ch
Autor:
Henry, Danielle
Les extrémités des chromosomes contiennent des répétitions de séquences d’ADN appelées télomères qui empêchent l’activation inopportune de la réponse aux dommages de l'ADN afin de préserver l'intégrité génomique. Les télomères rac
Externí odkaz:
http://hdl.handle.net/1866/24728
Autor:
Ashby J. Morrison
Publikováno v:
Molecular Metabolism, Vol 38, Iss, Pp 100973-(2020)
Molecular Metabolism
Molecular Metabolism
Background ATP-dependent chromatin remodelers are evolutionarily conserved complexes that alter nucleosome positioning to influence many DNA-templated processes, such as replication, repair, and transcription. In particular, chromatin remodeling can
Publikováno v:
G3 Genes|Genomes|Genetics. 8:1095-1102
Chromatin remodeling and histone modifying enzymes play a critical role in shaping the regulatory output of a cell. Although much is known about these classes of proteins, identifying the mechanisms by which they coordinate gene expression programs r
Autor:
Eleni Kallis, Mara Guariento, Kevin Schall, Jens Michaelis, Marianne Schwarz, Sebastian Eustermann, Karl-Peter Hopfner, Manuela Moldt
Publikováno v:
FEBS Letters. 592:318-331
Genome maintenance and integrity requires continuous alterations of the compaction state of the chromatin structure. Chromatin remodelers, among others the INO80 complex, help organize chromatin by repositioning, reshaping, or evicting nucleosomes. W
Autor:
Alicia N. Schep, William J. Greenleaf, Devin A. King, Ka Man Wong, Ashby J. Morrison, Graeme J. Gowans
Publikováno v:
Cell reports
Cell Reports, Vol 22, Iss 3, Pp 611-623 (2018)
Cell Reports, Vol 22, Iss 3, Pp 611-623 (2018)
SUMMARY Adaptive survival requires the coordination of nutrient availability with expenditure of cellular resources. For example, in nutrient-limited environments, 50% of all S. cerevisiae genes synchronize and exhibit periodic bursts of expression i